[PDF] Top 20 CD8 T cell differentiation during immune responses
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CD8 T cell differentiation during immune responses
... mammalian cell types, Listeria quickly disseminates to splenocytes and hepatocytes, whereas LCMV uses a ubiquitous receptor to infect ...monocyte differentiation into TNFα and NO secreting cells (TipDCs: ... Voir le document complet
212
Transcriptional regulation of effector CD8+ T cell differentiation and molecular dysfunction during HIV-1 infection
... HIV-specific CD8+ T cell response which peaks just prior to the decline in viremia and is important in maintaining the viral load at stable levels (Koup, Safrit et ...of CD8+ T cells in controlling ... Voir le document complet
192
To Investigate the Necessity of STRA6 Upregulation in T Cells during T Cell Immune Responses
... that, during evolution, mammals might have experienced vitamin A deficiencies in certain periods or regions in the ...all cell types for vitamin A uptake, its function should be revealed in immune ... Voir le document complet
13
P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells
... that CD8+ CTL can be primed by intradermal immuniza- tion (in buccal mucosa or skin) with a protein Ag com- bined with adjuvants inducing local secretion of the chemokine ...CTL responses was induced by ... Voir le document complet
2
Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses
... TRP1 is a self-antigen that can be presented on H-2D b , although the native epitope binds poorly to the MHC groove due to an alanine at the 9 th position anchor residue. Substitution of this alanine for methionine ... Voir le document complet
29
Dendritic cell differentiation and immune tolerance to insulin-related peptides in Igf2-deficient mice
... Dendritic Cell Differentiation and Immune Tolerance to Insulin-Related Peptides in Igf2-Deficient Mice 1 Isabelle Hansenne, 2 * Chantal Renard-Charlet,* Roland Greimers, † and Vincent Geenen* There ... Voir le document complet
7
CD8[superscript +] T-cell Responses Rapidly Select for Antigen-Negative Tumor Cells in the Prostate
... of immune responses to sculpt the antigen repertoire of spontaneously arising tumors is less ...T cell responses, prostate tumor histopathology, and total survival were measured, there was no ... Voir le document complet
17
Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses.
... IEC during immune responses, suggesting a possible cooperation of these ligands in peripheral lymphocyte ...an immune-priv- ileged site, the anterior chamber of the eye ... Voir le document complet
10
Epigenetic regulation of innate immune responses to infection
... 1.3 DNA methylation In mammals, DNA methylation occurs primarily at the fifth carbon of cytosine residues that are followed by a guanine (CpG dinucleotides). Overall, mammalian genomes are very rich in DNA methylation ... Voir le document complet
169
Deciphering anti-HCMV HLA-E-restricted unconventional CD8 T-cell responses in seropositive HCMV+ hosts
... circulating CD8 αβT cells at a time ...UL40 CD8 are effector memory T cells that appear early post-infection as monoclonal/oligoclonal populations and persist for ...UL40 CD8 T cells belong to the ... Voir le document complet
2
Commensal-specific immune responses at the intestinal mucosa
... somatic cell nuclear transfer (SCNT) that carries a monoclonal TCR (Vα2 Vβ6) isolated from pTreg cells sorted from ...Treg cell conversion of CD4+ T cells isolated from TN/RAGKO mice or WT ... Voir le document complet
219
Host innate immune responses to Acinetobacter baumannii infection
... replication, cell adhesion and cytotoxicity, biofilm formation, immune evasion, and interaction with other bacteria during a polymicrobial infection ( Lee et ...innate immune responses, ... Voir le document complet
17
IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1alpha and Impairing Dendritic Cell Functions during Leishmania Infection
... Visceral leishmaniasis (VL) is a good example of dysregulated balance between inflammato- ry and anti-inflammatory responses. VL is a potentially lethal disease caused by Leishmania donovani and L. ... Voir le document complet
22
Targeting CD8 T-Cell Metabolism in Transplantation
... memory CD8 T-cell population is heavily affected ( 35 , 36 ...effector CD8 response, they were unable to form a CD8 memory population after bacterial infection ( 37 ...TRAF6-deficient ... Voir le document complet
9
Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
... the cell type or develop- mental stage of an organism, one or another enhancer or enhancer combination can be used by a given gene to ensure a proper spatiotemporal expression pattern or to allow robust- ness of ... Voir le document complet
22
Early CD4+ T Cell Responses Are Associated with Subsequent CD8+ T Cell Responses to an rAd5-Based Prophylactic Prime-Boost HIV Vaccine Strategy
... cellular responses and antibody responses in this ...antibody responses were available during follow-up, limiting the correla- tion analyses to a small number of time ...of immune ... Voir le document complet
11
CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals
... T cell–depleted ...cohort responses to various stimuli with 77% overall classification accuracy, whereas it classified the responses of PBMCs from HIV+ donors to adaptive and innate immune ... Voir le document complet
29
Phenotyping of Adaptive Immune Responses in Inflammatory Diseases
... T cell clonality and/or TCR af finity measurements ( 13 , 14 , 16 ) ( Figures 1A, C ...T cell reactivity in patients ( 17 – 19 ) as well as clonality and af finity differences between mild and severe COVID-19 ... Voir le document complet
9
Differentiation of human dendritic cell subsets for immune tolerance induction
... T cell pro- liferation induction ability [6] ...T cell stimulatory ability [7] ...IL-10. During the last decades, significant advances have been made in establishing methods to manipulate DCs in ... Voir le document complet
7
Natural killer cells promote early CD8 T cell responses against cytomegalovirus
... antiviral CD8 T cell responses, and, therefore, that excessive levels of IFN-a can have a direct negative impact on antiviral immune cell responses in a manner that is ... Voir le document complet
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