ﺽﻴﻷﺍ ﺕﺎﺠﺘﻨﻤ ﺩﻴﺩﺤﺘ ﻭ لﺼﻓﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻱﻭﻨﺎﺜﻟﺍ ﺘﺒﻨﻠﻟﺔLycium arabicum.L

ﻲﻤﻠﻌﻟﺍ ﺙﺤﺒﻟﺍ ﻭ ﻲﻟﺎﻌﻟﺍ ﻡﻴﻠﻌﺘﻟﺍ ﺓﺭﺍﺯﻭ ﺔﻨﻴﻁﻨﺴﻗ ﻱﺭﻭﺘﻨﻤ ﺔﻌﻤﺎﺠ

ﺔﻘﯿﻗﺪﻟا مﻮﻠﻌﻟا ﺔﯿﻠـﻛ ءﺎـﯿﻤﯿـﻜﻟا ﻢﺴـﻗ

ﺐﯿﺗﺮﺘﻟا ﻢﻗر ...

ﻞﺴﻠﺴﺘﻟا ﻢﻗر ...

ﺓﺭﻜﺫﻤ

ﻡﻭﻠﻌﻟﺍ ﻲﻓ ﺭﻴﺘﺴﺠﺎﻤﻟﺍ ﺓﺩﺎﻬﺸ لﻴﻨﻟ ﺔﻤﺩﻘﻤ ﺔﻴﻭﻀﻋ ﺀﺎﻴﻤﻴﻜ ﺹﺼﺨﺘ

ﻨﻟﺍ ﺀﺎﻴﻤﻴﻜ ﺔﺒﻌﺸ ﺕﺎﺒ

ﻥﺍﻭﻨﻋ ﺕﺤﺘ

ﻡﻴﺩﻘﺘ :

ﺔﻠﻴﻬـﺴ ﺔﻨﺍﻭﺭـﺸ

ﺔﺸﻗﺎﻨـﻤﻟﺍ ﺔﻨﺠـﻟ :

ﺎـﺴﻴﺌﺭ ﺔﻨﻴﻁﻨﺴـﻗ ﻱﺭﻭﺘﻨـﻤ ﺔﻌﻤﺎـﺠﺒ ﺫﺎـﺘﺴﺃ ﻭﻴﻨﺘ ﻥﻤﺤﺭﻟﺍ ﺩﺒﻋ . ﺩ - ﺎـﻓﺭﺸﻤ ﺔﻨﻴﻁﻨﺴـﻗ ﻱﺭﻭﺘﻨـﻤ ﺔﻌﻤﺎـﺠﺒ ﺫﺎـﺘﺴﺃ ﻲﻁﺍﻭﻏ ﺢﻟﺎـﺼ . ﺩ - ﺎـﻨﺤﺘﻤﻤ ﺔﻨﻴﻁﻨﺴﻗ ﻱﺭﻭﺘﻨﻤ ﺔ ﻌﻤﺎﺠﺒ ﺭﻀﺎﺤﻤ ﺫﺎﺘﺴﺃ ل ﺎـﻜﻋ ﺢﻟﺎـﺼ . ﺩ - ﺎـﻨﺤﺘﻤﻤ ﺔﻨﻴﻁﻨﺴﻗ ﻱﺭﻭﺘﻨﻤ ﺔ ﻌﻤﺎﺠﺒ ﺭﻀﺎﺤﻤ ﺫﺎﺘﺴﺃ ﻱﺩﻴﺍﺯ ﻕﻭﺭﺎـﻓ . ﺩ -

ﺭﺒﻤﺴﻴﺩ

2007

ﺽﻴﻷﺍ ﺕﺎﺠﺘﻨﻤ ﺩﻴﺩﺤﺘ ﻭ لﺼﻓ ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻱﻭﻨﺎﺜﻟﺍ

ﺘﺒﻨﻠﻟ

ﺔ

Lycium arabicum.L

ﺃ ﺇ ﻱﺪﻬﺟ ﺓﺮﻤﺛﻭ ﻞﻤﻌﻟﺍ ﺍﺬﻫ ﻱﺪﻫ ﺎﻤﻬﻈﻔﺣ ﻲﻣﺃﻭ ﻲﺑﺃ ﻥﻮﻜﻟﺍ ﻲﻓ ﻱﺪﻟ ﺎﻣ ﻰﻠﻏﺃ ﻰﻟ

ﷲﺍ

ﺔﻨﻴﺴﺣ ﺔﻴﻟﺎﻐﻟﺍ ﻲﺘﺧﺃ ﻰﻟﺇ ﺔﺻﺎﺧﻭ ﺍﺮﻴﻐﺻﻭ ﺍﺮﻴﺒﻛ ﺔﻠﺋﺎﻌﻟﺍ ﺩﺍﺮﻓﺃ ﻊﻴﻤﺟ ﻰﻟﺇ

ﻲﺗﺎﻘﻳﺪﺻ ﻰﻟﺇ :

ﺯ ،ﺔﺒﻴﺗﺭ ﻮﻛ ،ﺔﻠﻴﻬﺳ ،ﺔﺨﻴﻟ

،ﺓﺪﻌﺳ ،ﻝﺎﻨﻣ ،ﻥﺎﻨﺣ ،ﺔﺒﻴﻃ ،ﺔﻴﻫﺯ ،ﺓﺮﻫﺯ،ﺮﺛ

،ﺔﻳﺯﻮﻓ ،ﺓﺩﺭﻭ ،ﻝﺎﻣﺃ ،ﻝﺎﻨﻣ ،ﺓﺮﻴﻨﻣ ،ﺔﻤﻴﺳﻭ

،ﺓﺩﺭﻭ ،ﺩﺎﻌﺳ ،ﺔﺤﻴﻠﺻ ،ﻝﺍﻮﻧ ،ﺔﻨﻳﺮﺒﺻ

،ﺓﺩﺎﻴﻣ ،ﺀﺎﻤﺳﺃ ﺳ

ﻪﻴﻤ ﺔﻨﻴﻤﺳﺎﻳ ،ﺔﺸﺋﺎﻋ ،ﺔﻤﻴﺴﻧ ،

ﺮﺒﺨﻤﻟﺍ ﻲﻓ ﻲﺗﻼﻴﻣﺯﻭ ﻲﺋﻼﻣﺯ ﻰﻟﺇ :

،ﺎﻴﻓﻭﺭ ،ﻡﻼﺣﺃ ،ﺯﻭﺮﻴﻓ ،ﺯﻭﺮﻴﻓ ،ﻥﺎﻤﻳﺮﻧ ،ﺔﻨﻴﺴﺣ

ﻴﻜﺳ ،ﺔﻜﻴﺴﻣ،ﻡﻼﺣﺃ ﻨ

ﻻﺯ ﺭﺎﻤﻋ ،ﺔ ﺶﻳﻭﺭﺩ ﻝﺎﻤﻛ ،ﺭﺍﻮﻨﻴﻛ ﻦﺑ ﺪﻴﺷﺭ ،ﻲﻗ

ﻞﻳﻮﻄﻟﺍ ﺪﻤﺣﺃ ﻱﺫﺎﺘﺳﺃ ﻰﻟﺇ ﻴﻌﺑ ﻭﺃ ﺐﻳﺮﻗ ﻦﻣ ﻲﻧﺪﻋﺎﺳ ﻦﻣ ﻞﻛ ﻰﻟﺇ ﺪ

ﻞﻤﻌﻟﺍ ﺍﺬﻫ ﺯﺎﺠﻧﺇ ﻰﻠﻋ ﺓﺭﺪﻘﻟﺍ ﻲﻧﺎﻄﻋﺃ ﻱﺬﻟﺍ ﻞﺟﻭ ﺰﻋ ﷲ ﺮﺒﻛﻷﺍ ﺪﻤﺤﻟﺍﻭ ﻝﻭﻷﺍ ﺮﻜﺸﻟﺍ .

ﺫﺎﺘﺳﻷﺍ ﻰﻟﺇ ﻞﻳﺰﺠﻟﺍ ﺮﻜﺸﻟﺎﺑ ﻡﺪﻘﺗﺃ ﺢﻟﺎﺻ ﻲﻃﺍﻮﻏ

ﻞﻤﻌﻟﺍ ﺍﺬﻫ ﻰﻠﻋ ﻑﺍﺮﺷﻹﺍ ﻪﻟﻮﺒﻗ ﻰﻠﻋ ﻰﻠﻋﻭ

ﺚﺤﺒﻟﺍ ﺍﺬﻫ ﺯﺎﺠﻧﻹ ﻪﺗﺍﺪﻋﺎﺴﻣ ﻞﻛ .

ﺫﺎﺘﺳﻸﻟ ﺮﻜﺸﻟﺍ ﻞﻳﺰﺠﺑ ﻡﺪﻘﺗﺃ ﻥﺎﻤﺣﺮﻟﺍ ﺪﺒﻋ ﻮﻴﻨﺛ

ﺔﻨﺠﻠﻟﺍ ﺔﺳﺎﺋﺭ ﻪﻟﻮﺒﻗ ﻰﻠﻋ .

ﻦﻳﺫﺎﺘﺳﻷﺍ ﻰﻟﺇ ﺮﻜﺸﻟﺍ ﻞﻳﺰﺠﺑ ﻡﺪﻘﺗﺃ ﻕﻭﺭﺎﻓ ﻱﺪﻳﺍﺯ

ﻭ ﻝﺎﻜﻋ ﺢﻟﺎﺻ ﻩﺬﻫ ﺔﺸﻗﺎﻨﻣ ﺎﻤﻬﻟﻮﺒﻗ ﻰﻠﻋ

ﻟﺍ ﺔﻟﺎﺳﺮ . ﺫﺎﺘﺳﻸﻟ ﻞﻳﺰﺠﻟﺍ ﺮﻜﺸﻟﺍﻭ ﻥﺎﻨﺘﻣﻻﺎﺑ ﻡﺪﻘﺗﺃ ﺎﻤﻛ ﺪﻤﺣﺃ

ﻞﻳﻮﻄﻟﺍ ﺔﻤﻴﻘﻟﺍ ﻪﺤﺋﺎﺼﻧﻭ ﻪﺗﺪﻋﺎﺴﻣ ﻞﻛ ﻰﻠﻋ

ﻞﻤﻌﻟﺍ ﺍﺬﻬﻟ ﺯﺎﺠﻧﺇ ﺔﻠﻴﻃ .

ﺭﻮﺘﻛﺪﻟﺍ ﺮﺒﺨﻣ ﺩﺍﺮﻓﺃ ﻰﻟﺇ ﻞﻳﺰﺠﻟﺍ ﺮﻜﺸﻟﺎﺑ ﻡﺪﻘﺗﺃ ﺮﻫﺎﻄﻟﺍ ﻲﻠﻴﻬﺳ

ﺔﺻﺎﺧﻭ ﺐﻟﺎﻄﻟﺍ

ﺪﻴﻟﻭ ﻰﻠﻋ

ﻲﻟ ﺎﻬﻣﺪﻗ ﻲﺘﻟﺍ ﺕﺍﺪﻋﺎﺴﻤﻟﺍ .

ﻰﻠﻋ ﻲﻧﺪﻋﺎﺳ ﻦﻣ ﻞﻜﻟ ﺮﻜﺸﻟﺍ ﻞﻳﺰﺠﺑ ﻡﺪﻘﺗﺃ ﻩﺬﻫ ﺯﺎﺠﻧﺇ

ﺯ ﻲﺑﺭﺩ ﺎﺘﻘﻴﻓﺭ ﺔﺻﺎﺧﻭ ﺔﻟﺎﺳﺮﻟﺍ ﺔﺨﻴﻟ

ﺮﺛﻮﻛ ﺓﺮﻫﺯ ، ﺔﻤﻴﺳﻭ ،ﺔﻠﻴﻬﺳ ﻲﺗﺎﻘﻳﺪﺻﻭ ﺔﺒﻴﺗﺭﻭ .

ﺮﺒﺨﻤﻟﺍ ﻲﻓ ﻲﺗﻼﻴﻣﺯﻭ ﻲﺋﻼﻣﺯ ﻰﻟﺇ ﻞﻳﺰﺠﻟﺍ ﺮﻜﺸﻟﺎﺑ ﻡﺪﻘﺗﺃ ﻥﺃ ﻰﺴﻧﺃﻻ ﺎﻤﻛ

.

ﺔﺤﻔﺼﻟﺍ

ﻉﻭﻀﻭﻤﻟﺍ

1 .........

3 .........

ﻊﺠﺍﺭﻤﻟﺍ لوﻷا ﻞﺼﻔﻟا

...

.

4 .........

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻫﺎﻤ

4 ......

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻤﻫﺃ

5 .........

ﻱﻭﻴﺤﻟﺍ ﻉﺎﻨﻁﺼﻻﺍ

5 ...... (ﻙﻴﻤﻴﻜﻴﺸﻟﺍ ﺽﻤﺤ ﻕﻴﺭﻁ) ﻰﻟﻭﻷﺍ ﺔﻠﺤﺭﻤﻟﺍ

7 ......... (ﺕﻼﺨﻟﺍ ﻕﻴﺭﻁ) ﺔﻴﻨﺎﺜﻟﺍ ﺔﻠﺤﺭﻤﻟﺍ

8 ...(نﻮﻜﻟﺎﺸﻟا ﻖﯾﺮﻃ)ﺔﺜﻟﺎﺜﻟا ﺔﻠﺣﺮﻤﻟا

9 .........

ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﻜﻴﻬﻟﺍ ﻰﻠﻋ ﺔﻴﻟﺍﺩﺒﺘﺴﻻﺍ ﺕﺎﻋﻭﻤﺠﻤﻟﺍ ﺕﻴﺒﺜﺘ

9 ......

لﻴﺴﻜﻭﺭﺩﻴﻬﻟﺍ ﺕﺎﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ -

9 .........

لﻴﺘﻴﻤﻟﺍ ﺕﺎﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ

10 ......

ﺭﻜﺴﻟﺍ ﺕﺎﺌﻴﺯﺠ ﺕﻴﺒﺜﺘ

10 .........

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ ﺔﻴﺌﺎﻴﻤﻴﻜﻟﺍ ﺔ ﺴﺍﺭﺩﻟﺍ ﻕﺭﻁ

10 ......

ﺎﻬﻨﻋ ﻑﺸﻜﻟﺍ

11 ........

ﺹﻼﺨﺘﺴﻻﺍ

11

......

ﺔﻴﺘﺎﺒﻨﻟﺍ ﺓﺩﺎﻤﻟﺍ

11

.........

ﺹﻼﺨﺘﺴﻹﺍ

13 ......

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻘﻨﺘ ﻭ لﺼﻓ

13 .........

لﺼﻔﻟﺍ

13 .......

ﺔﻴﺭﻴﻀﺤﺘﻟﺍ ﺔﻘﻴﻗﺭﻟﺍ ﺔﻘﺒﻁﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ

14 .........

ﻕﺭﻭﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ

15 ......

ﺩﻭﻤﻌﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ

15 .........

ﺔﻴﻘﻨﺘﻟﺍ

16 ......

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ ﺔﻴﻭﻴﻨﺒﻟﺍ ﺔﺴﺍﺭﺩﻟﺍ

16 .........

ﺔﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜﻟﺍ ﺹﺍﻭﺨﻟﺍ

16 ......

ﻲﻋﺎﻌﺸﺘﺴﻹﺍ ﻥﻭﻠﻟﺍ

16 .........

ﺱﺎﺒﺤﻨﻻﺍ لﻤﺎﻌﻤ

17 ...

ﺔﯿﺠﺴﻔﻨﺒﻟا قﻮﻓ ﺔﻌ ﺷﻷا ﺔﯿﻓﺎﯿﻄﻣ

18 ......

لﻭﻨﺎﺜﻴﻤﻟﺍ ﻲﻓ لﻭﻨﻭﻓﻼﻔﻟﺍﻭ ﻥﻭﻓﻼﻔﻟﺍ ﻑﻴﻁ - 1

18 ...

ﻒﺷاﻮﻛ دﻮﺟو ﻲﻓ لﻮﻧﻮﻓﻼﻔﻟاو نﻮﻓﻼﻔﻟا ﻒﯿﻃ - 2

18 .………..………..

NaOH

18 ...………..……….. NaOAc

18 ..………...………

NaOAc+H

BO

19 ...………

AlCl

19

.

AlCl

+HCl

22 ......

ﺔﻠﺘﻜﻟﺍﺔﻴﻓﺎﻴﻁﻤ

22 ........

R.M.N-

H ﻥﻭﺘﻭﺭﺒﻠﻟ ﻲﺴﻴﻁﺎﻨﻐﻤﻟﺍ ﻱﻭﻭﻨﻟﺍ ﻥﻴﻨﺭﻟﺍ ﺔﻴﻓﺎﻴﻁﻤ

22 .....

ﺔﻴﺘﺎﻤﻭﺭﻷﺍ ﺕﺎﻨﻭﺘﻭﺭﺒﻟﺍ - 1

22 .........

A ﺔﻘﻠﺤﻟﺍ ﺕﺎﻨﻭﺘﻭﺭﺒ

23 ......

B ﺔﻘﻠﺤﻟﺍ ﺕﺎﻨﻭﺘﻭﺭﺒ

24 .........

C ﺔﻘﻠﺤﻟﺍ ﺕﺎﻨﻭﺘﻭﺭﺒ

24 .....

ﺔﻴﺘﺎﻔﻴﻟﻷﺍ ﺕﺎﻨﻭﺘﻭﺭﺒﻟﺍ -

24 ........

لﻴﺴﻜﻭﺜﻴﻤﻟﺍ ﺔﻋﻭﻤﺠﻤ ﺕﺎﻨﻭﺘﻭﺭﺒ

24 ......

ﺭﻜﺴﻟﺍ ﺕﺎﻨﻭﺘﻭﺭﺒ

24 ........

ﺭﻜﺴﻟﺍ ﺔﻴﺩﺎﺤﺃ ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠﻟﺍ

25 .....

ﺭﻜﺴﻟﺍ ﺔﻴﺌﺎﻨﺜ ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠﻟﺍ

26

.........

ﺔﻴﻀﻤﺤﻟﺍ ﺔﻫﺎﻤﻹﺍ

27 ........

ﻊﺠﺍﺭﻤﻟﺍ ﻲﻨﺎﺜﻟﺍ لﺼﻔﻟﺍ

...

...

30 ......

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻟﺍ ﻑﻴﺭﻌﺘ

30 ......

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻟﺍ ﻡﻴﺴ

30 ......

ﻥﻭﺭﻴﺒﻟﺍ ﺔﻘﻠﺤ ﻰﻠﻋ ﺔﻟﺩﺒﺘﺴﻤ ﺕﺎﻨﻴﺭﺎﻤﻭﻜ

30 ......

ﺔﻴﻨﻴﺯﻨﺒﻟﺍ ﺔﻘﻠﺤﻟﺍ ﻰﻠﻋ ﺔﻟﺩﺒﺘﺴﻤ ﺕﺎﻨﻴﺭﺎﻤﻭ

31 ..........

ﻥﻴﺭﺎﻤﻭﻜﻭﻨﺍﺭﻴﻓ

31 ......

ﻥﻴﺭﺎﻤﻭﻜﻭﻨﺍﺭﻴﺒ

32 ......

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻟﺍ ﻊﻴﺯﻭﺘﻭ ﻡ ﻜﺍﺭﺘ ،ﺩﺠﺍﻭﺘ

32 ......

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻠﻟ ﺔﻴﺠﻭﻟﻭﻴﺒﻟﺍ ﺔﻴﻟﺎﻌﻔﻟﺍ

32 ......

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻠﻟ ﻱﻭﻴﺤﻟﺍ ﻉﺎﻨﻁﺼﻻﺍ

33 ......

ﺎﻬﺘﻴﻘﻨﺘﻭ ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻟﺍ ﺹﻼﺨﺘﺴﺍ ﻕﺭﻁ

33

..........

ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻠﻟ ﺔﻴﻭﻴﻨﺒﻟﺍ ﺔﺴﺍﺭﺩﻟﺍ

33 ...... ^UV

ﺔﻴﺠﺴﻔﻨﺒﻟﺍ ﻕﻭﻓ ﺔﻌﺸ ﻷﺍ ﻑﻴﻁ -

34 ...... ^RMN

ﻲﺴﻴ ﻁﺎﻨﻐﻤﻟﺍ ﻱﻭﻭﻨﻟﺍ ﻥﻴﻨﺭﻟﺍ ﻑﻴﻁ -

34 ...... ^RMN.1H

ﻥﻭﺘﻭﺭﺒﻠﻟ ﻲﺴﻴﻁﺎﻨﻐﻤﻟﺍ ﻱﻭﻭﻨﻟﺍ ﻥﻴﻨﺭﻟﺍ ﻑﻴﻁ

34 .........^{.. RMN.13C}

ﻥﻭﺒﺭﻜﻠﻟ ﻲﺴﻴﻁﺎﻨﻐﻤﻟﺍ ﻱﻭﻭﻨﻟﺍ ﻥﻴﻨﺭﻟﺍ ﻑﻴﻁ

35 ......

ﻊﺠﺍﺭﻤﻟﺍ ﺙﻟﺎﺜﻟﺍ لﺼﻔﻟﺍ

...

...

...

36 ......

ﻲﺘﺎﺒﻨﻟﺍ ﻑﺼﻭﻟﺍ

36 .........

ﺕﺎﺒﻨﻠﻟ ﻲﻤﺎﻅﻨﻟﺍ ﻑﻴﻨﺼﺘﻟﺍ

37 ......^Lyciumﻉﺍﻭﻨﺃ

37 .........

ﺔﻴﺘﺎﺒﻨﻟﺍ ﺓﺩﺎﻤﻟﺍ

38 ......

ﺕﺎﺒﻨﻠﻟ ﺔﻴﺒﻁﻟﺍ ﺕﻻﺎﻤﻌﺘﺴ ﻹﺍ

38 ......

ﻲﻓﺍﺭ ﻏﻭﻴﻠﺒﺒﻟﺍ ﺙﺤﺒﻟﺍ

41

...

ﺹﻼﺨﺘﺴﻻﺍ ﺕﺎﻴﻠﻤﻋ

42 ......^...

لﺼﻔﻟﺍ -

44 ......

ﻲﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜﻟﺍﺩﻭﻤﻌﻟﺍ -1

44 ......

ﻕﺍﺭﻭﻷﺍ ﺹﻠﺨﺘﺴﻤ

46 ......

ﺭﻭﺩﺠﻟﺍ ﺹﻠﺨﺘﺴﻤ - ﺏ -1-

49

......^.

ﻊﺠﺍﺭﻤﻟﺍ ﻊﺒﺍﺭﻟﺍ لﺼﻔﻟﺍ

...

...

...

51 ......^CS1

ﺏﻜﺭﻤﻠﻟ ﻱﻭﻴﻨﺒﻟﺍ لﻴﻠﺤﺘﻟﺍ

58 .........^CS2

ﺏﻜﺭﻤﻠﻟ ﻱﻭﻴﻨﺒﻟﺍ لﻴﻠﺤﺘﻟﺍ

62 ......^CS3

ﺏﻜﺭﻤﻠﻟ ﻱﻭﻴﻨﺒﻟﺍ لﻴﻠﺤﺘﻟﺍ

65 .........

ﺔﻤﺩﻘﻤ : ﺔﻴﺒﻁﻟﺍ ﺏﺎﺸﻋﻷﺎﺒ ﺔﺠﻟﺎﻌﻤﻟﺍ ﺕﺒﺎﻏ ﻥﺇﻭ ،ﺀﺍﻭﺩﻟﺍ ﻭ ﺀﺍﺫﻐﻟﺍ ﻲﻓ ﺎﻤﺎﻫ ﺍﺭﻭﺩ ﺏﻌﻠﺘ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻭ ﻡﺩﻘﻟﺍ ﺫﻨﻤ

ﻥﺃ ﺩﻌﺒ ،ﺎﻬﺒ ﺔﻘﺌﻼﻟﺍ ﺔﻨﺎﻜﻤﻟﺍ ﻕﻘﺤﺘﻟ ﻡﻭﻴﻟﺍ ﺩﻭﻌﺘ ﻲﻬﻓ ،ﺎﻴﻋﺎﻨﻁﺼﺍ ﺔﻏﺎﺼﻤﻟﺍ ﺔﻴﻭﺩﻷﺍ لﻀﻔﺒ ﻥﻤﺯﻟﺍ ﻥﻤ ﺓﺭﺘﻓ ﺔﻴﻤﻠﻋ ﺱﺴﺃ ﻰﻠﻋ ﺔﻤﺌﺎﻗ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺔﺠﻟﺎﻌﻤﻟﺍ ﺕﺤﺒﺼﺃ

، ﻭ ﻌﻤ ﻥﺃ ﺭﻜﺫﻟﺎﺒ ﺭﻴﺩﺠﻟﺍ ﺭﺜﻜﺃ ﻰﻠﻋ ﻱﻭﺘﺤﺘ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻡﻅ

ﺔﻴﺭﻁﻋ ﺕﻭﻴﺯ ﻱﻭﺤﻴ ﻡﻭﺜﻟﺍ ﻼﺜﻤﻓ ،ﺩﺤﺍﻭ ﻥﺁ ﻲﻓ ﺕﺎﺒﺎﺒﻁﺘﺴﺍ ﺓﺩﻋ ﺎﻬﻟ ﻥﻭﻜﻴ ﻲﻟﺎﺘﻟﺎﺒ ﻭ ﺔﻟﺎﻌﻓ ﺓﺩﺎﻤ ﻥﻤ ﻲﻓ ﺩﻴﻔﺘ ﺔﻴﺘﻴﺭﺒﻜ ﺩﺍﻭﻤ ﻭ ،ﻡﻀﻬﻟﺍ ﻰﻠﻋ ﺩﻋﺎﺴﺘ ﺭﺌﺎﻤﺨﻭ ،ﺕﺎﺒﺎﻬﺘﻟﻼﻟ ﺓﺩﺎﻀﻤ ﺝﻼﻋ

ﻲﻨﺎﻴﺭﺸﻟﺍ ﺭﺘﻭﺘﻟﺍ ﻉﺎﻔﺘﺭﺍ

ﺔﻴﺜﻼﺜﻟﺍ ﻡﻭﺤﺸﻟﺍ ﻭ لﻭﺭﺘﺴﻟﻭﻜﻟﺍ ﻭ .

ﻭ ﻥﻵﺍ ﻰﺘﺤ لﺍﺯﺎﻤ ﺕﺍﺫ ﺭﻴﻗﺎﻘﻌﻟﺍ ﻥﻤ ﺭﻴﺒﻜ ﺩﺩﻋ

لﺼﻷﺍ ﻭ ﻥﻴﻟﺎﺘﻴﺠﻴﺩﻟﺎﻜ ﺓﺭﻴﺒﻜ ﺔﻴﺠﻼﻋ ﺔﻤﻴﻗ ﺍﺫ ﻲﺘﺎﺒﻨﻟﺍ

،ﻥﻴﺭﺒﺴﻷﺍ ﺎﻬﺒﺒﺴﺘ ﻲﺘﻟﺍ ﺕﺎﻓﻵﺍ ﺔﺠﻟﺎﻌﻤﻟ ﻯﺭﺨﺃ ﺕﺎﺴﺍﺭﺩ ﻙﺎﻨﻫ ﻥﺃ ﺎﻤﻜ

ﺎﻴﻤﺤﻟﺍ ﺕ ،ﺔﻴﺒﻁﻟﺍ ﺕﺎﺘﺎﺒﻨﻟﺎﺒ ﺔﺤﺸﺍﺭﻟﺍ

ﺎﻬﻨﻤ ﺭﻜﺫﻨ

Hyssopus

لﺒﺠﻟﺍ لﻴﻠﻜﺇ ﻭ

Rosemarinus

ﻉﺎﻨﻌﻨﻟﺍ ﻭ

Meniha و

Inula

.

ﻙﻟﺫﻟﻭ ﻭﻘﻟﺍ ﻥﻜﻤﻴ ل

ﺭﻭﺩ ﺔﻴﺒﻁﻟﺍ ﺕﺎﺘﺎﺒﻨﻠﻟ ﻥﺃ ﻡﺎﻫ

ﻲﻓ ﻴﺜﻜﻟﺍ ﺔﺠﻟﺎﻌﻤ ﺭ

،ﺽﺍﺭﻤﻷﺍ ﻥﻤ ﺀﺍﺩ ﻥﻤ ﷲﺍ لﺯﻨﺃ ﺎﻤﻓ

ﻪﻟ لﺯﻨﺃ ﻭ ﻻﺇ ﺀﺍﻭﺩ

.

،ﺕﺍﺩﻴﻭﻠﻗ ،ﺕﺎﻨﻴﺒﺭﺘ ،ﺕﺍﺩﻴﻨﻭﻓﻼﻓ ﻥﻤ ﺔﻴﺌﺎﻴﻤﻴﻜﻟﺍ ﺕﺎﺒﻜﺭﻤﻟﺍ ﻥﻤ لﺌﺎﻫ ﻡﻜ ﻰﻠﻋ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻱﻭﺘﺤﺘ ﺎﻨﻴﺭﺎﻤﻭﻜ ﺕ

...

ﺍﺭﺎﺸﺘﻨﺍ ﺭﺜﻜﻷﺍ ﻱﻭﻨﺎﺜﻟﺍ ﺽﻴﻷﺍ ﺞﺘﺍﻭﻨ ﻥﻤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺩﻌﺘ ﻭ ﺦﻟﺍ ﺙﻴﺤ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺔﻜﻠﻤﻤﻟﺍ ﻲﻓ

ﻥﻤ ﺭﺜﻜﺃ ﺭﺼﺤ ﻡﺘ ﻱﺩﻴﻭﻨﻭﻓﻼﻓ ﺏﻜﺭﻤ 4000

] 1

.[

ﻑﺎﺸﺘﻜﺍ ﻥﻤ ﻪﻴﻓ ﺎﻤﻟ ﺔﻴﻤﻫﻷﺍ ﺔﻴﺎﻏ ﻲﻓ ﺭﻤﺃ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻥﻤ ﺎﻬﻟﺯﻋ ﻡﺘﻴ ﻲﺘﻟﺍ ﺕﺎﺒﻜﺭﻤﻟﺍ لﻭﺤ ﺙﺎﺤﺒﺃ ﺀﺍﺭﺠﺇ ﻥﺇ ﻫ ﻲﻓﻭ ،ﺭﻴﺒﻜ ﻊﻔﻨ ﺕﺍﺫ ﺔﻴﻭﺩﻷ ﺫ

ﺭﺎﻁﻹﺍ ﺍ ﻭ ﻲﺘﺎﺒﻨﻟﺍ لﺼﻷﺍ ﺕﺍﺫ ﺔﻴﻌﻴﺒﻁﻟﺍ ﺕﺎﺠﺘﻨﻤﻟﺍ ﺭﺒﺨﻤ ﻲﻓ ﻭ

ﻀﻌﻟﺍ ﻉﺎﻨﻁﺼﻻﺍ ﻱﻭ

) ﺀﺎﻴﻤﻴﻜﻟﺍ ﻡﺴﻗ (

ﺕﺎﺘﺎﺒﻨ ﺩﺤﻷ ﺔﻴﺌﺎﻴﻤﻴﻜﻭﺘﻴﻓ ﺔﺴﺍﺭﺩﺒ ﺎﻨﺭﺒﺨﻤ ﻥﻤ ﺙﺤﺒ ﻕﻴﺭﻓ ﻡﺎﻗ

ﺕﺎﺒﻨ ﻭﻫﻭ ﺭﺌﺍﺯﺠﻟﺍ ﺞﺴﻭﻌﻟﺍ

(Lycium arabicum.Boiss.)

ﺔﻴﻨﺎﺠﻨﺫﺎﺒﻟﺍ ﺔﻠﺌﺎﻌﻟﺍ ﻰﻟﺇ ﻲﻤﺘﻨﻤﻟﺍ

(Solanaceae)

ﻨﻴﺭ ﺎﻤﻭﻜ ﺏﻜﺭﻤ لﺼﻓ ﻉﺎﻁﺘﺴﺍ ﺙﻴﺤ ﻲ

ﻥﻴﺘﻴﻟﻭﺒﻭﻜﺴﻟﺍ ﻭﻫﻭ

(Scopoletine)

ﻭ ﺭﺎﻴﻁ ﺏﻜﺭﻤ32

Volatiles) (Huiles

ﺔﻠﺘﻜﻟﺍ ﺔﻴﻓﺎﻴﻁﻤﺒ ﺔﻁﺒﺘﺭﻤﻟﺍ ﺔﻴﺯﺎﻐﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜﻟﺍ لﺎﻤﻌﺘﺴﺎﺒ

(C.G.-S.M.)

ﺎﻤﻜ

ﺕﺎﺒﻨﻟﺍ ﺍﺫﻫ ﺕﺎﺼﻠﺨﺘﺴﻤﻟ ﺔﻴﺭﻴﺘﻜﺒﻟﺍ ﺩﻀ ﺔﻴﻟﺎﻌﻔﻟﺍ ﺔﺴﺍﺭﺩ ﺕﻤﺘ

] 2

ﺔﺴﺍﺭﺩﺒ ﺎﻨﻤﻗ ﺙﺤﺒﻟﺍ ﺍﺫﻬﻟ ﻻﺎﻤﻜﺘﺴﺍﻭ [

ﺘﻟﺍ ﺽﺍﺭﻤﻷﺍ ﻑﻠﺘﺨﻤ ﻥﻤ ﻱﻭﺍﺩﺘﻠﻟ ﻲﺒﻌﺸﻟﺍ ﺏﻁﻟﺍ ﻲﻓ ﺕﺎﺒﻨﻟﺍ ﺍﺫﻫ لﻤﻌﺘﺴﻴﻭ ﻪﻟ ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻯﻭﺘﺤﻤﻟﺍ ﻲ

ﺭﻌﺸﻠﻟ ﺔﻐﺒﺼﻜ لﻤﻌﺘﺴﻴ ﺎﻤﻜ ﻥﻴﻌﻟﺍ ﺏﻴﺼﺘ .

ﺞﺴﻭﻌﻟﺍ ﺓﺭﺠﺸ ﻥﻤ ﻰﺴﻭﻤ ﻰﺼﻋ ﻥﺃ ﻡﻴﺭﻜﻟﺍ ﻥﺍﺭﻘﻠﻟ ﻥﻴﺭﺴﻔﻤﻟﺍ ﺽﻌﺒ ﺭﻜﺫ ﺩﻘﻓ ﺔﻴﺨﻴﺭﺎﺘﻟﺍ ﺔﻴﺤﺎﻨﻟﺍ ﻥﻤ ﺎﻤﺃ ﻫ ﻰﻤﺴﻴ ﻯﺩﻟ ﺫ

ﻡﻀﺘ ﻲﺘﻟﺍﻭ ﺔﻴﻨﺎﺠﻨﺫﺎﺒﻟﺍ ﺔﻠﺌﺎﻌﻟﺍ ﻥﺈﻓ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺭﻅﻨﻟﺍ ﺔﻬﺠﻭ ﻥﻤﻭ ﺎﻤﺃ ،ﺩﻭﻬﻴﻟﺍ ﺭﺠﺸﺒ ﺕﺎﺒﻨﻟﺍ ﺍ

ﻲﻟﺍﻭﺤ ﻭ ﺱﻨﺠ 96

ﻉﻭﻨ 3000 ] 3

ﻲﻓ ﻉﺯﻭﺘﺘ [

ﺎﻜﻴﺭﻤﺃ ﻲﻓ ﺔﺼﺎﺨ ﺓﺭﻭﺼﺒ ﺯﻜﺭﻤﺘﺘﻭ ﻡﻟﺎﻌﻟﺍ ﺀﺎﺤﻨﺃ ﻑﻠﺘﺨﻤ

ﺎﻬﺘﺎﺘﺎﺒﻨ ﺏﻠﻏﺃ ﻡﻁﺎﻤﻁﻟﺍﻭ ﻥﺎﺠﻨﺫﺎﺒﻟﺍﻭ ﺎﻁﺎﻁﺒﻟﺍ لﺼﺃ ﺙﻴﺤ ﺔﻴﺒﻭﻨﺠﻟﺍ

) 3/4

ﻑﻨﺼﻟﺍ ﻰﻟﺇ ﻲﻤﺘﻨﺘ ( Solanum

ﺔﻠﺌﺎﻌﻟﺍ ﺕﺒﺴﻨ ﻪﻴﻟﺇﻭ

] 4

،[

لﺜﻤ ﺔﻴﺩﺎﺼﺘﻗﻻﺍ ﺔﻴﻤﻫﻷﺍ ﺕﺍﺫ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻥﻤ ﺭﻴﺜﻜﻟﺍ ﺔﻠﺌﺎﻌﻟﺍ لﻤﺸﺘ ﺱﻁﺎﻁﺒﻟﺍ :

(Solanum tuberosum)

ﻤﻁﻟﺍ ﻭ ﻡﻁﺎ

(Lycopersicon exulentu)

، ﻥﺎﺠﻨﺩﺎﺒﻟﺍ

(Solanum melorgina)

، ﺎﻤﻜ

ﻫ ﻡﻫﺃﻭ ﺔﻤﺎﻫ ﺕﺍﺩﻴﻭﻠﻗ ﻰﻠﻋ ﺎﻬﺌﺍﻭﺘﺤﻻ ﺔﻴﺒﻁ ﺔﻴﻤﻫﺃ ﻪﻟ ﺎﻬﺘﺎﺘﺎﺒﻨ ﻥﻤ ﺭﻴﺜﻜﻟﺍ ﻥﺃ ﺫ

ﺕﺎﺘﺎﺒﻨﻟﺍ ﻩ ﺎﻨﻭﺩﻼﺒﻟﺍ:

(Atropa

belladonna)

، ﺓﺭﻭﺘﺍﺩﻟﺍ

stramonium) (Datura

، ﻥﺍﺭﻜﺴﻟﺍ

(Hyoscyamus muticus)

ﻴﺜﻜﻟﺍﻭ ﺭ ﻡﺎﺴ ﺎﻬﻨﻤ

لﺜﻤ ﺏﺌﺫﻟﺍ ﺏﻨﻋ

(Solanum nigrum)

ﺥﺍﺭﻔﻟﺍ ﻡﺴﻭ

(Withania somnifera)

ﻴﻤﺘﺘﻭ ﺯ ﻫ ﺕﺎﺘﺎﺒﻨ ﺫ

ﻠﺌﺎﻌﻟﺍ ﻩ ﺔ

ـﺒ : ﻤﺨ ﻰﻠﻋ ﻱﻭﺘﺤﻴ ﻊﻠﻁﻟﺍ ،ﺔﻤﻅﺘﻨﻤﻟﺍ ﺭﺎﻫﺯﻷﺍ ﺴ

ﺔﻤﻴﺸﻤﻟﺍﻭ ﺓﺭﻫﺯﻟﺍ ﺭﻭﺤﻤ ﻰﻠﻋ لﺌﺎﻤ ﻉﺎﺘﻤﻟﺍ ،ﺔﻴﺩﺴﺃ ﺔ

ﺔﻴﺌﺎﻋﻭﻟﺍ ﻡﺯﺤﻟﺍ ﻲﻓ ﻲﻠﺨﺍﺩ ﺀﺎﺤﻟ ﺩﻭﺠﻭ ﻊﻤ ﺔﻤﺤﺸﺘﻤ . [5]

ﺭﻭﺸﻨﻤﻟﺍ ﻲﻓ ﺩﺭﻭ ﺩﻗﻭ ﺍ ﺀﺍﺭﺤﺼ ﻥﺃ [6]

ﺍﻭﻨﻷﺍ ﻰﻠﻋ ﻱﻭﺘﺤﺘ ﺭﺌﺍﺯﺠﻟ ﻉ

ﺔﻴﻟﺎﺘﻟﺍ :

ü Lycium arabicum Boiss.; Lycium intricatum L.

ü Solanum nigrum L.

ü Withania adpressa Coss.

ﻠﻋ ﺔﺴﺍﺭﺩﻟﺍ ﺔﻠﻘﻟ ﺍﺭﻅﻨﻭ ﻰ

ﻰﻨﻏ ﻡﺩﻋ ﻥﻤ ﻡﻏﺭﻟﺎﺒﻭ ،ﺎﻬﻟ ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻯﻭﺘﺤﻤﻟﺍ ﺔﺴﺍﺭﺩﺒ ﺎﻨﻤﻗ ﺩﻘﻠﻓ ﺔﺘﺒﻨﻟﺍ ﻩﺫﻫ

ﺎﻨﻨﺃ ﻻﺇ ﺕﺎﺒﻜﺭﻤﻟﺍ ﻥﻤ ﻉﻭﻨﻟﺍ ﺍﺫﻬﺒ ﺔﺘﺒﻨﻟﺍ ﻥﻴﻴﺩﻴﻨﻭﻓﻼﻓ ﻥﻴﺒﻜﺭﻤ لﺼﻓ ﺎﻨﻌﻁﺘﺴﺍ

.

ﺎﻨﺜﺤﺒ لﻭﺎﻨﺘﻴ ﺫﻫ

،لﻭﺼﻓ ﺔﻌﺒﺭﺃ ﺍ ﺹﻠﺨﺘﺴﻤﻟﺍ ﻥﻤ ﺔﺠﺭﺨﺘﺴﻤﻟﺍ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻨﺒ ﺔﻓﺭﻌﻤ ﻭﻫ ﺎﻨﻓﺩﻫ ﻥﺃ ﺎﻤﺒﻭ

ﺭﻜﺫ ﻭ ﺕﺎﺒﻜﺭﻤﻟﺍ ﻩﺫﻬﺒ ﻑﻴﺭﻌﺘﻠﻟ ﺍﺭﻭﺤﻤ لﻭﻷﺍ لﺼﻔﻟﺍ ﻥﻭﻜﻴ ﻥﺃ ﺎﻨﻴﺄﺘﺭﺍ ﺩﻘﻓ ﺕﺎﺒﻨﻠﻟ ﻲﻟﻭﻨﺎﺘﻭﺒﻟﺍ ﺎﻬﺼﺌﺎﺼﺨ

ﺎﻴﻨﻘﺘﻟﺍ ﻰﻟﺇ ﺔﻓﺎﻀﺇ ﺔﻴﺠﻭﻟﻭﻴﺒﻟﺍ ﺎﻬﺘﻴﻟﺎﻌﻓ ﻭ ﺔﻴﺌﺎﻴﻤﻴﻜﻟﺍ ﺎﻬﺘﻴﻨﺒ ﺩﻴﺩﺤﺘﻟ ﺔﻌﺒﺘﻤﻟﺍ ﺕ

.

،ﺕﺎﻨﻴﺭﺎﻤﻭﻜﻟﺍ لﻭﺤ ﺔﻤﺎﻋ ﺔﺴﺍﺭﺩ ﺕﻨﺎﻜ ﻲﻨﺎﺜﻟﺍ لﺼﻔﻟﺍ ﻲﻓﻭ ﺀﺯﺠﻟﺍ ﻲﻓ ﺎﻨﻗﺭﻁﺘﻓ ﺙﻟﺎﺜﻟﺍ لﺼﻔﻟﺍ ﻲﻓ ﺎﻤﺃ

ﺔﻌﺒﺘﻤﻟﺍ ﺔﻔﻠﺘﺨﻤﻟﺍ ﺔﻴﻠﻤﻌﻟﺍ ﻕﺭﻁﻟﺍ ﺡﺭﺸﻟ ﻲﻨﺎﺜﻟﺍ ﺀﺯﺠﻟﺍ ﺎﻨﺼﺼﺨﻭ ﺕﺎﺒﻨﻠﻟ ﺔﻴﺌﺎﻴﻤﻴﻜﻟﺍ ﺔﺴﺍﺭﺩﻟﺍ ﻰﻟﺇ ﻪﻨﻤ لﻭﻷﺍ

،ﺔﻴﻘﻨﺘﻭ ﺹﻼﺨﺘﺴﺇ ﻥﻤ ﺕﺎﺒﻨﻟﺍ ﺔﺴﺍﺭﺩ ﻲﻓ ﺎﻬﻴﻠﻋ لﺼﺤﻤﻟﺍ ﺞﺌﺎﺘﻨﻟﺍ ﻑﻠﺘﺨﻤ ﺔﺸﻗﺎﻨﻤﺒ ﺎﻨﻤﻗ ﺔﻴﺎﻬﻨﻟﺍ ﻲﻓﻭ

.

[1]- Medié-Sarié, M., Jasprica, I. Smoleié-Bubalo, A., Mornar, A. (2004) ^«Optimization of Chromatographic Conditions in Thin Layer Chromatography of Flavonoids and Phenolic Acids^», Croatica Chemica Acta, 77(1-2), 361-366.

[2]- Chaabi, M. (2003) ^« Thèse de magister^», Constantine^.

[3]- Wink, M. (2003) ^« Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective^», Phytochemistry, 64 (1), 3-19.

[4]- Guignard, J. L (1994) ^«Botanique^», ed. Masson ( 9^ème eddition), Paris, , Tome II, 187-188.

د ﺪﻌﺳ ﻢﯿھاﺮﺑإ يﺮﻜﺷ . )

1994

، (

"

ﺔﯾﺮھﺰﻟاتﺎﺗﺎﺒﻨﻟا –

ﺎﮭﺗﺄﺸﻧ ﺎھرﻮﻄﺗ - ﺎﮭﻔﯿﻨﺼﺗ-

"

ﺑﺎﻄﻣ ، ﻲﺑﺮﻌﻟا ﺮﻜﻔﻟا راد ﻊ .

[5]-

[6]- Ozanda, P. (1985) ^« Flore de sahara septentrional et central ^» ed. C.N.R.S.

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻫﺎﻤ -I :

ﻥﺎﻘﻴﺴ ﻭﺭﻭﻫﺯﻭ ﻕﺍﺭﻭﺃ ﻥﻤ ﺕﺎﺒﻨﻟﺍ ﺀﺍﺯﺠﺃ ﻑﻠﺘﺨﻤ ﻲﻓ ﺩﺠﺍﻭﺘﺘ ﺀﺍﺭﻔﺼ ﺔﻴﺘﺎﺒﻨ ﺕﺎﻐﺒﺼ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺭﻭﺫﺠﻭ

] 1

.[

ﻥﻤ ﻥﻭﻜﺘﺘ ﺎﻴﺒﺴﻨ ﺔﻁﻴﺴﺒ ﺔﻴﺴﺎﺴﺃ ﺔﻴﻨﺒﺒ ﺯﻴﻤﺘﺘ ﺫ 15

ﻥﺎﻨﺜﺇ ﺕﺎﻘﻠﺤ ﺙﻼﺜ ﻰﻠﻋ ﺔﻋﺯﻭﻤ ﻥﻭﺒﺭﻜ ﺓﺭ

ﺔﺴﻨﺎﺠﺘﻤ ﺎﻬﻨﻤ

)

،A B

ﺔﺴﻨﺎﺠﺘﻤ ﺭﻴﻏ ﺔﺜﻟﺎﺜﻟﺍﻭ (

) C

لﻜﺸﻟﺍ (1

A

B C

لﻜﺸﻟﺍ :1

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ ﻱﺩﻋﺎﻘﻟﺍ لﻜﻴﻬﻟﺍ

ﺔﻁﻴﺴﺒ ﺔﻴﻭﻴﻨﺒ ﻎﻴﺼﺒ ﺩﺠﺍﻭﺘﺘ ﻭﺃ ﻡﺩﻌﻨﺘ ﻭ ﺔﻴﻗﺍﺭﻟﺍ ﺕﺎﺘﺎﺒﻨﻟﺍ ﺔﻓﺎﻜ ﻲﻓ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺩﺠﻭﺘ ﺎﻴﻨﺩﻟﺍ ﺕﺎﺘﺎﺒﻨﻟﺍ ﻲﻓ

] 2

ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠ لﻜﺸﺒ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺔﻴﻠﺨﻟﺍ ﻯﻭﺘﺴﻤ ﻰﻠﻋ ﺩﺠﺍﻭﺘﺘ ﺙﻴﺤ [

ﺫ ﺹﻭﺼﺨﻟﺎﺒ ﺯﻜﺭﻤﺘﺘ ﻭ ﺀﺎﻤﻟﺍ ﻲﻓ ﺔﺒﺍﻭ

ﻤﺃ ﺓﻭﺠﻔﻟﺍ ﻲﻓ ﺎ

ﻥﻭﻜﺘ ﻲﺘﻟﺍ ﻭ ﺕﺎﻨﻭﻜﻴﻠﺠﺃ لﻜﺸﺒ ﺎﻫﺩﺠﺍﻭﺘ ﺫ

ﻤﻟﺍ ﻲﻓ ﺔﺒﺍﻭ ﺫ

ﺔﻴﺒﻁﻘﻟﺍ ﺭﻴﻏ ﺕﺎﺒﻴ )

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ

لﻴﺴﻜﻭﺜﻴﻤﻟﺍ ﺓﺩﻴﺩﻋ (

ﺕﺎﺒﻨﻟﺍ ﺢﻁﺴ ﻯﻭﺘﺴﻤ ﻲﻠﻋ ﻊﻀﻭﺘﺘ ﺎﻬﻨﺈﻓ )

ﺼﺎﺨ ﻕﺍﺭﻭﻷﺍ ﺔ (

ﺩﺍﻭﻤﻟ ﺔﻤﺯﻼﻤ ﻥﻭﻜﺘ ﺙﻴﺤ

ﺔﻴﻠﻴﻓﻭﭙﻴﻟ ﻯﺭﺨﻷﺍ ﻲﻫ ﺓﺯﺭﻔﻤ .

ﻫ ﻅﺤﻼﺘﻭ ﺫ

ﺔﻓﺎﺠﻟﺍ ﻪﺒﺸ ﻭ ﺔﻓﺎﺠﻟﺍ ﻕﻁﺎﻨﻤﻟﺍ ﺕﺎﺘﺎﺒﻨ ﻲﻓ ﺓﺭﻫﺎﻅﻟﺍ ﻩ

] 3 .[

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻤﻫﺃ -II :

ﺎﻬﻨﻤ ﺭﻜﺫﻨ ﺔﻴﺠﻼﻋﻭ ﺔﻴﺠﻭﻟﻭﻴﺒ ﺭﺍﻭﺩﺃ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ :

- ﻥﻴﻤﺎﺘﻴﻔﻟﺍ ﺔﻴﺼﺎﺨ ﻲﻫ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ ﺔﻴﺠﻼﻋ ﺔﻴﻟﺎﻌﻓ ﻡﻫﺃ ﺎﺸﻨ ﺏﺒﺴﺒ P

ﺽﺎﻔﺨﻨﺍ ﻩﺎﺠﺘﺍ ﻲﻗﺍﻭﻟﺍ ﺎﻬﻁ

ﻟ ﺔﻴﻭﻤﺩﻟﺍ ﺕﺍﺭﻴﻌﺸﻟﺍ ﺔﻴﺤﺎﻤﺴ ﺫ

ﻱﺩﻴﺭﻭﻟﺍ ﺯﺠﻌﻟﺍ ﺔﺠﻟﺎﻌﻤﻟ ﺔﻴﻭﺩﺄﻜ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺭﺒﺘﻌﺘ ﻙﻟ

.[4]

- ﺔﻴﻭﻴﺤ ﺕﺍﺩﺎﻀﻤﻜﻭ ﺕﺍﺭﺸﺤﻠﻟ ﺕﺍﺩﻴﺒﻤﻜ لﻤﻌﺘﺴﺘ ﺕﺎﻨﻭﻓﻼﻓﻭﺯﻴﻻﺍ ﺔﺼﺎﺨ ﻭ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ

- لﺜﻤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ ﻊﻴﻁﺘﺴﺘ )

ﻭﻨﺎﻓﻼﻔﻟﺍ ،لﻭﻨﻭﻓﻼﻔﻟﺍ ،ﻥﻭﻓﻼﻓﻭﺯﻴﺍ ،ﻥﻭﻜﻟﺎﺸﻟﺍ ﻥ

( ﺩﻴﻠﻘﺘ

ﺎﻬﻁﻴﺸﻨﺘﻭ ﺕﺎﻨﻴﺠﻭﺭﺘﺴﻷﺍ ﺏﻜﺭﻤ لﺜﻤ

[5] Génistéine

.

- لﺜﻤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ )

ﻥﺎﻓﻼﻔﻟﺍ ،ﻥﻭﻓﻼﻔﻟﺍ (

ﺕﺎﻴﺭﻁﻔﻟﺍ ﻁﻴﺒﺜﺘ ﺔﻴﺼﺎﺨ ﺎﻬﻟ

.[6]

- ﺱﻭﺭﻴﻓ ﺎﻬﻴﻓ ﺎﻤﺒ ﺕﺎﺴﻭﺭﻴﻔﻠﻟ ﺓﺩﺎﻀﻤ ﺔﻴﻟﺎﻌﻓ ﺎﻬﻟ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ .[7] HIV

- لﺜﻤ ﺕﺎﻨﻭﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ

tangeretin

،

nobiletin

ﺎﻬﻟ ﻴﻨﺎﻁﺭﺴﻟﺍ ﺎﻴﻼﺨﻟﺍ ﺭﺎﺸﺘﻨﺍ ﻊﻨﻤ ﻰﻠﻋ ﺓﺭﺩﻘﻟﺍ ﺔ

] 8

.[

- ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻼﺜﻤﻓ ﺱﻔﻨﺘﻟﺍ ﺔﻴﻠﻤﻋ ﻲﻓ لﺨﺩﺘﺘ ﻲﺘﻟﺍ ﺕﺎﻤﻴﺯﻨﻹﺍ ﻥﻤ ﺩﻴﺩﻌﻟﺍ ﻁﻴﺒﺜﺘ ﻰﻠﻋ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﻤﻌﺘ

ﻥﻴﺒ ﺔﻴﺌﺎﻨﺜ ﺔﻁﺒﺍﺭ ﺎﻬﻟ ﻲﺘﻟﺍ

C2

ﻭ

C3

ﺩﻨﻋ ﺔﻴﻨﻭﺘﻴﻜ ﺔﻔﻴﻅﻭ ﻭﺃ

C4

ﺔﻘﻠﺤﻟﺍ ﻲــﻓ ﺎﻬﻟ ﻭﺃ ﺕﺎﻋﻭﻤﺠﻤ B

ﻲﻓ لﻴﺴﻜﻭﺭﺩﻴﻬﻟﺍ

C3'

،

C4'

،

C5'

ﺘ ﻡﻴﺯﻨﺇ ﻁﻴﺒﺜﺘ ﻊﻴﻁﺘﺴ

NADH-oxidase ]

9 [

.

- ﻡﻴﺯﻨﺇ ﻁﻴﺒﺜﺘ ﻲﻓ ﺔﻴﻟﺎﻌﻓ ﺎﻬﻟ ﻥﻭﻜﺘ ﻥﻴﺘﺭﻭﺎﺠﺘﻤ لﻴﺴﻜﻭﺭﺩﻴﻫ ﻲﺘﻋﻭﻤﺠﻤ ﻰﻠﻋ ﻱﻭﺘﺤﺘ ﻲﺘﻟﺍ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ

5-lipoxygenase

ﻭ

ﻢﯾﺰﻧإ cyclo-oxygenase ]

10 [ .

- ﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺏﻌﻠﺘ ﺕﺎﺘﺎﺒﻨﻟﺍ ﺔﻴﺎﻤﺤ ﻲﻓ ﺎﻤﺎﻫ ﺍﺭﻭﺩ ﺕ

ﺕﺎﺒﻭﺭﻜﻤﻠﻟ ﺓﺩﺎﻀﻤ ﺔﻴﻟﺎﻌﻓ ﺕﺍﺫ ﺩﺍﻭﻤ ﺎﻬﻨﻭﻜﻟ ﺍﺫﻫﻭ

] 11

،[ [11^’] .

-III ﻱﻭﻴﺤﻟﺍ ﻉﺎﻨﻁﺼﻻﺍ :

ﺔﻴﻌﻴﺒﻁﻟﺍ ﺎﻫﺭﺩﺎﺼﻤ لﺨﺍﺩ ﺓﺭﻴﺨﻷﺍ ﻩﺫﻫ ﻥﻴﻭﻜﺘﻟ ﺔﻘﻴﺭﻁ ﻻﺇ ﺱﻴﻟ ﺔﻴﻌﻴﺒﻁﻟﺍ ﺕﺎﺒﻜﺭﻤﻠﻟ ﻱﻭﻴﺤﻟﺍ ﻉﺎﻨﻁﺼﻻﺍ ﻥﺇ ﻬﻤﻠﺤﻟﺍ ،ﺔﻠﻜﻟﻷﺍ ،ﻉﺎﺠﺭﻹﺍ ،ﺓﺩﺴﻜﻷﺍ ﺕﻼﻋﺎﻔﺘ ﻕﻴﺭﻁ ﻥﻋ ﻙﻟﺫﻭ ﺔﺼﺎﺨ ﺕﺎﻤﻴﺯﻨﺇ ﺩﻭﺠﻭﺒ ﺍﺫﻫﻭ ﺔ

. ﺔﻌﺒﺎﺘﻤﻟﻭ

ﺏ ﺔﻤﻭﺴﻭﻤﻟﺍ ﺭﺌﺎﻅﻨﻟﺍ لﺎﻤﻌﺘﺴﺎﺒ ﺓﺩﻋ ﺏﺭﺎﺠﺘ ﺀﺍﺭﺠﺇ ﻡﺘ ﻉﺎﻨﻁﺼﻻﺍ ﺍﺫﻫ ﺔﻴﻟﺁ

14C

،ﻊﺸﻤﻟﺍ ﺙﻴﺤ

- ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻠﻟ ﺔﺒﺴﻨﻟﺎﺒ ﻭ –

ﻡﻟﺎﻌﻟﺍ ﻅﺤﻻ

"

Robinson

"

ﺔﻨﺴ

1936 ] 12

ﻥﻴﺘﻴﻨﻴﺯﻨﺒﻟﺍ ﻥﻴﺘﺍﻭﻨﻟﺍ لﺍﺩﺒﺘﺴﺍ ﻥﺃ [

ﻠﺘﺴﻴ ﺎﻤﻤ ﺎﻴﺭﻫﻭﺠ ﻑﻠﺘﺨﻤ ﺔﻴﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺕﺎﺒﻜﺭﻤﻠﻟ

، ﻱﻭﻴﺤﻟﺍ ﻲﺜﺍﺭﻭﻟﺍ لﺼﻷﺍ ﺱﻔﻨ ﺎﻤﻬﻟ ﺱﻴﻟ ﻪﻨﺃ ﻡﺯ

ﻫ ﺭﺍﺭﻤﺘﺴﺎﺒ ﻭ ﺫ

ﻡﺘ ﺏﺭﺎﺠﺘﻟﺍ ﻩ

ﻥﺃ ﻰﻟﺇ لﺼﻭﺘﻟﺍ ﻫ

ﺫ ﻲﻫ ﻭ لﺤﺍﺭﻤ ﺙﻼﺜ لﻼﺨ ﻡﺘﻴ ﻉﺎﻨﻁﺼﻻﺍ ﺍ :

ﻰﻟﻭﻷﺍ ﺔﻠﺤﺭﻤﻟﺍ :

ﻙﻴﻤﻴﻜﻴﺸﻟﺍ ﺽﻤﺤ ﻕﻴﺭﻁü :

ﻡﻟﺎﻌﻟﺍ ﺕﺒﺜﺃ "

Davis

"

ﺔﻨﺴ

1955 ] 13

[

ﺔﻘﻠﺤﻟﺍ ﻥﻴﻭﻜﺘ ﻲﻓ ﻙﻴﻤﻴﻜﻴﺸﻟﺍ ﺽﻤﺤ ﺭﻭﺩ

) B

ﺔﻠﺴﻠﺴﻟﺍ ﻭ (

ﺔﻴﻨﻭﺒﺭﻜﻟﺍ

) C3

ﺯﻭﻜﻭﻠﺠﻟﺍ ﻥﻤ ﺎﻗﻼﻁﻨﺍ (

) لﻜﺸﻟﺍ (2

:

Glucose

CHO CHOH CHOH CH₂OP

+

COOH CHOPH2

CH₂

1

COOH CO CH₂ CHOH CHOH CHOH CH₂OP

=

COOH

OH

HO OH

PO O COOH

OH OH HO

O

4-Phospho erythrose

Ac.Phosphenol pyruvique

Ac.2-oxo-3-desoxy-7- phosphoglucoheptanoique

2

Ac.Dehydroquinique

H₂O

OH OH O

COOH

OH OH HO

COOH

NADPH,H⁺ NADPH⁺

OH OH O

COOH

ADP ATP

Ac.5-Phosphoshikimique Ac.Shiquimique Ac.5-Dehydroshikimique

DEP

Pi P

O OH O

COOH

P ^C

CH₂

COOH

O OH COOH

C CH₂

Pi COOH

O OH

C CH₂

COOH

Ac.3-Enolpyruvyl-5- phosphoshikimique

Ac.Chorismique Ac.Prephénique

3 H⁺

CO₂

OH CH2

COOH H₂N

OH

CH2COCOCH

OH CH CH COOH

transamination 4

Ac.p-Hydroxycinnamique (Ac.p-coumarique)

Ac.p-hydroxyphenyl alanine(tysosine)

Ac.p-Hydroxyphenyl pyruvique

CH₂COCOOH C

HOO

لﻜﺸﻟﺍ :2

ﺽﻤﺤ ﻥﻴﻭﻜﺘ

Ac.p-coumarique

ﻙﻴﻤﻜﻴﺸﻟﺍ ﺽﻤﺤﺒ ﺍﺭﻭﺭﻤ ﺯﻭﻜﻭﻠﺠﻟﺍ ﻥﻤ ﺎﻗﻼﻁﻨﺍ

ﻥﻤ ﻑﻭﺭﺤﻟﺎﺒ ﺎﻬﻟ ﺎﻨﺯﻤﺭ ﻲﺘﻟﺍ ﺕﺎﻤﻴﺯﻨﻷﺍ ﻰﻟﺇ 1

ﻲﻟﺍﻭﺘﻟﺍ ﻰﻠﻋ ﻲﻫ 4 :

1- Aldolase, 3-désoxy-o-arabinoheptulosonate-7-phosphate synthase ou DHAP synthase.

2- Déshydroquinate synthase ; 3- Préphénate déshydrogénase ; 4- Tyrosine ammonia-lyase.

لﻭﺤﺘﻴ ﻡﺜ

Ac.p-coumarique

ﻰﻟﺇ

p- coumaroyl- CoA

) لﻜﺸﻟﺍ (3 .

لﻜﺸﻟﺍ

:3

لﻭﺤﺘ

Ac.p-coumarique

ﻰﻟﺇ

p-coumaroylCoA

ﺔﻴﻨﺎﺜﻟﺍ ﺔﻠﺤﺭﻤﻟﺍ :

ﺕﻼﺨﻟﺍ ﻕﻴﺭﻁü :

ﻴﺴﻜﻭﺒﺭﻜ ﺔﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ ﻡﺘﻴ ل

ﻕﻓﺍﺭﻤ لﻴﺘﺴﺃ ﻊﻤ -

ﻡﻴﺯﻨﺍ

) Acétyl-CoA

ﺓﺩﺤﻭ ﻪﻨﻋ ﺞﺘﻨﻴﻓ ( (Malonyl-

) CoA)

لﻜﺸﻟﺍ (4

.

C O H₃C

S CoA + CO₂

ATP ADP

C O

HO

CH₂ C O

SCoA

Acétyl CoA Malonyl CoA

ﻟﺍ لﻜﺸ :4

لﻴﻜﺸﺘ

Malonyl-CoA

ﺎﻗﻼﻁﻨﺍ ﻥﻤ

Acétyl-CoA

ﻭ

CO2

C

OH

C

OH

S

O CoA

HOO

p-coumaroylCoA Ac.p-coumarique

CoA

ﺔﺜﻟﺎﺜﻟا ﺔﻠﺣﺮﻤﻟا :

ü نﻮﻜﻟﺎﺸﻟا ﻖﯾﺮﻃ :

ﺔﻘﻠﺤﻟﺍ لﻜﺸﺘﺘ

) A

ﻑﺜﺎﻜﺘ ﻥﻤ (

phenylalaline ﻰﻟﻭﻷﺍ ﺔﻠﺤﺭﻤﻟﺍ ﺔﻠﻴﺼﺤ ﻊﻤ

)

p-coumaroyl-CoA (

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﻜﺎﻴﻫ ﻑﻠﺘﺨﻤ ﺎﻬﻨﻤ ﺭﺩﺤﻨﺘ ﻲﺘﻟﺍ ﺔﻴﺴﺎﺴﻷﺍ ﺓﺍﻭﻨﻟﺍ ﻭﻫ ﻭ ﻥﻭﻜﻟﺎﺸﻟﺍ ﻲﻁﻌﻴ )

لﻜﺸﻟﺍ (5

]

.[14

O HO

OH

OH

O

O HO

OH

OH

O 1'

2' 4'

5

7 2

3

Flavanone:Naringénine Flavone:Apigénine flavone-synthase

Chalcone-isomerase

O HO

OH

OH

O 1'

2' 4'

5

7 2

3

OH

O HO

OH

OH

O OH

Dihydroflavonol:(2R,3R)-dihydrokaempférol Flavonol:kaempférol Flavonol-synthase

(2S)-Flavanone-3-hydroxylase

Dihydroflavonol-4-réductase

O HO

OH

OH

OH 1'

2' 4'

5

7 2

3

OH

O HO

OH

OH

1'

2' 4'

5

7 2

3

OH

Flavan-3,4-diol:Leucopélargonidol Flavan-3-ol:afzéléchol

O HO

OH

OH

OH

+ HO O

OH

OH

O-Glu +

3-O-glucosyl-transférase

Anthocyanidol:pélargonidol Anthocyanoside:pélargonidol-3-O-glucoside

O

Cl Cl

Chalcone OH

O CoA

p-coumaroyl-CoA S

HO OH

O OH

OH 1- phénylalanine ammonia lyase

2- chalcone-synthase + phénylalanine

لﻜﺸﻟﺍ

5

ﺘﻟﺍ :

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻡﺎﺴﻗﺃ ﻑﻠﺘﺨﻤ ﻥﻴﺒ ﺔﻴﻠﺨﺍﺩﻟﺍ ﺕﻻﻭﺤ

] 2

[

- IV ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﻜﻴﻬﻟﺍ ﻰﻠﻋ ﺔﻴﻟﺍﺩﺒﺘﺴﻻﺍ ﺕﺎﻋﻭﻤﺠﻤﻟﺍ ﺕﻴﺒﺜﺘ :

ﺍ ﺕﺎﻴﻠﻤﻋ ﻰﻟﺇ ﺎﺴﺎﺴﺃ ﺩﻭﻌﻴ ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻉﻭﻨﺘﻟﺍ ﻥﺇ ﻹ

ﺕﻼﻋﺎﻔﺘﻟﺍ ﻥﻤ ﻁﺎﻤﻨﺃ لﻼﺨ ﻡﺘﺘ ﻲﺘﻟﺍ ﺕﻴﺒﺜﺘﻟﺍ ﻭﺃ لﺍﺩﺒﺘﺴ

ﻜﺎﻤﺘﻟﺍ ﺕﻼﻋﺎﻔﺘﻜ ،ﻁﻤﻨ لﻜﺒ ﺔﺼﺎﺨ ﺕﺎﻤﻴﺯﻨﺇ ﺩﻭﺠﻭ ﻲﻓ ﺔﻴﻠﺴﻠﺴﺘﻟﺍ ﺩﺴﻜﻷﺍ ،ﺏ

ﺓ

،لﻴﺜﻴﻤﻟﺍ ﺕﻴﺒﺜﺘ ، ﺕﻴﺒﺜﺘ

ﺕﺎﻴﺭﻜﺴﻟﺍ .

-1- IV لﻴﺴﻜﻭﺭﺩﻴﻬﻟﺍ ﺕﺎﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ

:

ﺔﻘﻠﺤﻟﺍ لﻴﺴﻜﻭﺭﺩﻴﻫ ﺕﺎﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ ﻥﻋ لﻭﺅﺴﻤﻟﺍ ﻭﻫ ﻱﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﻜﻴﻬﻟﺍ ﻥﻴﻭﻜﺘ ﻁﻤﻨ ﻥﺇ ﺩﻌﺘﻭ ،A

ﻥﻴﻌﻀﻭﻤﻟﺍ ﻲﻓ لﺍﺩﺒﺘﺴﻻﺍ ﺔﻴﺌﺎﻨﺜ ﻥﻭﻜﺘ ﺎﻬﻨﻭﻜﻟ ﺔﻴﻠﺼﺃ ﺔﻴﻠﻴﺴﻜﻭﺭﺩﻴﻫ ﺕﺎﻋﻭﻤﺠﻤﻜ

،7

ﻫﻭ 5

ﺫ ﺔﺒﺴﻨﺒ ﺍ

90%

.

ﺔﻘﻠﺤﻟﺍ ﻱﻭﺘﺤﺘ ﺩﻗﻭ ﺭﺴﻔﻴﻭ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ ﻲﻓ ﺩﺤﺍﻭ لﻴﺴﻜﻭﺭﺩﻴﻫ ﻭﺃ ﺕﻼﻴﺴﻜﻭﺭﺩﻴﻫ ﺙﻼﺜ ﻰﻠﻋ A

ﺫ ﻙﻟ

ﻫ ﻥﻭﻜﺒ ﺫ لﻭﻸﻟ ﺍﺭﻴﺎﻐﻤ ﺎﻴﻭﻴﺤ ﺎﻋﺎﻨﻁﺼﺍ ﻊﺒﺘﺘ ﺓﺭﻴﺨﻷﺍ ﻩ .

ﺔﻘﻠﺤﻟﺍ ﻲﻓ ﺎﻤﺃ ﺩﻴﻫ ﻥﺎﻓ B

ﻊﻀﻭﻤﻟﺍ لﻴﺴﻜﻭﺭ ﻭﻫ4'

ﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻥﻴﻭﻜﺘ لﺒﻗ ﻪﺘﻴﺒﺜﺘ ﻡﺘﻴ ﻱﺫﻟﺍ ﺩﻴﺤﻭﻟﺍ

] 15

.[

-2-IV لﻴﺜﻴﻤﻟﺍ ﺕﺎﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ :

ﺏﻠﻁﺘﻴﻭ لﻴﺜﻴﻤﻟﺍ ﺎﻫﺩﻌﺒﻭ ﻻﻭﺃ لﻴﺴﻜﻭﺭﺩﻴﻬﻟﺍ ﺕﺒﺜﻴ ﺫ

ﺕﺎﻤﻴﺯﻨﺇ ﻥﻤ ﻉﺍﻭﻨﺃ ﺓﺩﻋ ﺩﻭﺠﻭ ﻙﻟ

O-methyl-transferase

ﻟﺎﺸﻟﺍ ﺓﺍﻭﻨ ﻥﻴﻭﻜﺘ لﺒﻗ لﻴﺜﻴﻤﻟﺍ ﺔﻋﻭﻤﺠﻤ ﺕﻴﺒﺜﺘ ﻰﻠﻋ لﻤﻌﻴ ﻥﻤ ﺎﻬﻨﻤ ﻭﻫ ﺎﻤﻜ ﻥﻭﻜ

ﺔﻟﺎﺤ ﻲﻓ لﺎﺤﻟﺍ

[16] 4-OH

ﻥﻭﻜﻟﺎﺸﻟﺍ ﻥﻴﻭﻜﺘ ﺩﻌﺒ ﺕﻴﺒﺜﺘﻟﺍ ﺔﻴﻠﻤﻌﺒ ﻡﻭﻘﻴ ﻥﻤ ﺎﻬﻨﻤﻭ ﻰﻠﻋ ﺓﺭﺩﺎﻗ ﻯﺭﺨﺃﻭ [17]

ﺩﺤﺍﻭﻟﺍ ﻥﻭﻜﻴﻠﺠﻷﺍ ﻰﻠﻋ لﻴﺜﻴﻤﻟﺍ ﺕﺎﻋﻭﻤﺠﻤ ﻥﻤ ﺩﻴﺩﻌﻟﺍ ﺕﻴﺒﺜﺘ )

لﻜﺸﻟﺍ (6

.

O

O

OH

OH

OH HO

SAM SAH

O

O

OH OMe

OH HO

Luteoline

Chrysoeriol O-methyl transférase

SAM : S-adénosyl methionine SAH : S-adénosyl homocystéine

لﻜﺸﻟﺍ :6

ﺏﻜﺭﻤﻟ ﻲﻤﻴﺯﻨﻷﺍ لﻴﻭﺤﺘﻟﺍ

Luteoline

ﻰﻟﺇ

Chrysoeriol

-3-IV ﺭﻜﺴﻟﺍ ﺕﺎﺌﻴﺯﺠ ﺕﻴﺒﺜﺘ

:

ﻰﻨﺒﻟﺍ ﻉﻭﻨﺘ ﻥﻤ ﺩﻴﻌﺒ ﺩﺤ ﻰﻟﺇ ﺩﻴﺯﺘ ﺔﻴﺜﻼﺜﻟﺍﻭ ﺔﻴﺌﺎﻨﺜﻟﺍ ،ﺔﻁﻴﺴﺒﻟﺍ ﺎﻬﻋﺍﻭﻨﺄﺒ ﺕﺎﻴﺭﻜﺴﻟﺍ ﺕﻴﺒﺜﺘ ﺔﻴﻠﻤﻋ ﻥﺇ ﺴﻟﺍ ﺭﻬﺸﺃ ﻥﻤﻭ ﺔﻴﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺯﻭﻨﻴﺒﺍﺭﻷﺍ ﻭ ﺯﻭﻨﻤﺍﺭﻟﺍ ،ﺯﻭﺘﻜﻼﺠﻟﺍ ،ﺯﻭﻜﻴﻠﺠﻟﺍ ﺩﺠﻨ ﺕﺎﻴﺭﻜ

...

ﻭ ﺦﻟﺍ ﻁﺒﺘﺭﺘ ﻲﺘﻟﺍ

ﺔﻁﺒﺍﺭ ﺔﻠﻜﺸﻤ ﺔﻴﻟﻭﻨﻴﻔﻟﺍ ﺕﻼﻴﺴﻜﻭﺭﺩﻴﻬﻟﺎﺒ

O- heteroside

.

ﻊﻗﻭﻤﻟﺍ ﻻﺍﺩﺒﺘﺴﺍ ﻊﻗﺍﻭﻤﻟﺍ ﺭﺜﻜﺃﻭ ﻥﻤ ﺭﺜﻜﺄﺒ ﺔﻓﻭﺭﻌﻤﻟﺍ ﺕﺎﻨﻭﻓﻼﻔﻠﻟ ﺔﺒﺴﻨﻟﺎﺒ 7

ﻊﻗﻭﻤﻟﺍﻭ ﺩﻴﺯﻭﺭﻴﺘﻴﺍ 650

3

ﺔﻓﻭﺭﻌﻤﻟﺍ ﺕﻻﻭﻨﻭﻓﻼﻔﻠﻟ ﺔﺒﺴﻨﻟﺎﺒ ﻥﻤ ﺭﺜﻜﺄﺒ

ﺩﻴﺯﻭﺭﻴﺘﻴﺍ 330 ]

18

ﺔﻤﻅﻨﺃ ﺩﻭﺠﻭ ﻲﻓ ﻡﺘﻴ ﺭﻜﺴﻟﺍ ﺕﻴﺒﺜﺘﻭ [

ﺔﺼﺎﺨ ﺔﻴﻤﻴﺯﻨﺇ

Glycosyltransferase

ﻊﻤ ﺩﻭﺠﻭ ﺭﻜﺴﻠﻟ ﺢﻨﺎﻤ )

لﻜﺸﻟﺍ (7 .

O

O

OH

OH

HO O

O

OH

OH Glu-O

UDP-GLU Glucosyltransférase

OH

OH O-Glu

OH

لﻜﺸﻟﺍ :7 ﻲﻓ ﺯﻭﻜﻴﻠﺠﻟﺍ ﺕﻴﺒﺜﺘ

C7

ﺯﻭﻜﻴﻠﺠﻠﻟ ﺢﻨﺎﻤﻭ ﻡﻴﺯﻨﺇ ﺩﻭﺠﻭ ﻲﻓ

ﻕﺭﻁ -V ﻴﺌﺎﻴﻤﻴﻜ ﻭﺘﻴﻔﻟﺍ ﺔﺴﺍﺭﺩﻟﺍ ﺔ

ﻔﻠﻟ ﺕﺍﺩﻴﻨﻭﻓﻼ :

- V 1 ﻥﻋ ﻑﺸﻜﻟﺍ - ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ

:

ﻡﻫﺃ ﻥﻤ ﺔﻘﻴﻗﺭﻟﺍ ﺔﻘﺒﻁﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ ﻭ ﺔﻴﺠﺴﻔﻨﺒﻟﺍ ﻕﻭﻓ ﺔﻌﺸﻷﺍ ﺔﻴﻓﺎﻴﻁﻤ ﻭ ﻕﺭﻭﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ ﺭﺒﺘﻌﺘ ﻭ ﺕﺎﻨﻭﻜﻴﻠﺠﻷﺍ ﻥﻋ ﻑﺸﻜﻠﻟ ﺍﺫﻫ ﻭ ﻡﺎﺨﻟﺍ ﺕﺎﺼﻠﺨﺘﺴﻤﻠﻟ ﻲﻟﻭﻷﺍ لﻴﻠﺤﺘﻠﻟ ﺔﻤﺩﺨﺘﺴﻤﻟﺍ لﻴﻠﺤﺘﻟﺍ ﻕﺭﻁ ﺎﻬﺒ ﺓﺩﻭﺠﻭﻤﻟﺍ ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠﻟﺍ .

ﺒﻟ ﺔﺒﺴﻨﻟﺎﺒﻓ لﺜﻤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌ

:

anthocyanines

،

chalcones

،

aurones

ﻰﻠﻋ ﺎﻴﺌﺭﻤ ﺎﻫﺯﻴﻴﻤﺘ ﻥﻜﻤﻴ

ﻕﻭﻓ ﺔﻌﺸﻷﺍ ﻡﺍﺩﺨﺘﺴﺎﺒ ﺭﺸﺎﺒﻤﻟﺍ ﺹﺤﻔﻟﺎﺒ ﺍﺫﻫ ﻭ ﺎﻫﺯﻴﻴﻤﺘﻟ ﻑﺸﺍﻭﻜﻟﺍ ﺽﻌﺒ ﻰﻟﺇ ﺄﺠﻠﻨﻓ ﺎﻫﺭﻴﻏ ﺎﻤﺃ ﻕﺭﻭﻟﺍ ﺩﻨﻋ ﺔﻴﺠﺴﻔﻨﺒﻟﺍ ﻡﻨ 365

ﻭﻴﻨﻤﻟﻷﺍ ﺩﻴﺭﻭﻠﻜﺒ ﺵﺭﻟﺍ ﺩﻌﺒ ﻭ لﺒﻗ ﻡ

AlCl3

ﺓﺭﺨﺒﻷ ﺔﺒﺴﻨﻟﺎﺒ ﺭﻤﻷﺍ ﻙﻟﺫﻜ ﻭ ،

ﺭﺩﺎﺸﻨﻟﺍ لﻭﻠﺤﻤ

NH3

ﺎﻌﺸﺘﺴﻹﺍ ﻉﻭﻨ ﻲﻓ ﺕﺍﺭﻴﻐﺘ ﺙﺩﺤﺘ ﺙﻴﺤ ، ﺯﻜﺭﻤﻟﺍ ﻉ

ﻥﻴﺒﻴ ﺎﻤﻜ )

لﻭﺩﺠﻟﺍ (1 ]

،19 20

:[

لﻭﺩﺠﻟﺍ :1

ﺭﻴﺜﺄﺘ

NH3

ﺕﺤﺘ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺽﻌﺒ ﻥﻭﻟ ﻰﻠﻋ UV

ﺔﻠﻤﺘﺤﻤﻟﺍ ﺔﻴﺌﺎﻴﻤﻴﻜﻟﺍ ﻎﻴﺼﻟﺍ UV ﺔﻌﺸﺃ ﺕﺤﺘ ﺔﻌﻘﺒﻟﺍ ﻥﻭﻟ ﻥﻭﺩ

NH3

^NH3 ﺩﻭﺠﻭﺒ

5-OH Flavones; 5-OH Flavonols (3-OR,4’-OH) ﺭﻔﺼﺃ ﻭﺃ ﺭﻔﺼﺃ ﺭﻀﺨﻤ

. ﺩﻭﺴﺃ– ﻲﺠﺴﻔﻨﺒ

Flavones ; Flavonols (3-OR, 5-OH, 4’-OH) Flavones (6-OH ou 8-OH)

ﻡﺩﻋ ﻭﺃ ﻑﻴﻔﻁ ﺭﻴﻐﺘ

ﻥﻭﻠﻟﺍ ﻲﻓ ﺭﻴﻐﺘﻟﺍ ﺩﻭﺴﺃ– ﻲﺠﺴﻔﻨﺒ

Flavones(5-OR) ; Flavonols (3-OR, 5-OR) ﻭﺃ ﺭﻀﺨﻤ ﺭﻔﺼﺃ

ﺭﻀﺨﻤ ﻕﺭﺯﺃ ﻕﺭﺯﺃ

Flavonols( 5-OH) ; Flavones (3-OH,5-OR) ﻡﺩﻋ ﻭﺃ ﻑﻴﻔﻁ ﺭﻴﻐﺘ

ﻥﻭﻠﻟﺍ ﻲﻓ ﺭﻴﻐﺘﻟﺍ ﻊﻗﺎﻓ ﺭﻔﺼﺃ ﺕﻫﺎﺒ ﺭﻔﺼﺃ ﻭﺃ

-2-V ﺹﻼﺨﺘﺴﻹﺍ :

ﺃ - ﺔﻴﺘﺎﺒﻨﻟﺍ ﺓﺩﺎﻤﻟﺍ :

ﺕﺍﺭﺜﺅﻤﻟﺍ ﻥﻋ ﺓﺩﻴﻌﺒ ﻥﻜﺎﻤﺃ ﻲﻓ ﺕﻅﻔﺤﻭ لﻅﻟﺍ ﻲﻓ ﺕﻔﻔﺠ ،ﺏﺌﺍﻭﺸﻟﺍ ﻥﻤ ﺕﻔﻅﻨ ،ﺔﻴﺘﺎﺒﻨﻟﺍ ﺓﺩﺎﻤﻟﺍ ﻑﻁﻗ ﻡﺘ ﺔﻴﺠﺭﺎﺨﻟﺍ )

ﺱﻤﺸﻟﺍ ﺔﻌﺸﺃ ،ﺔﺒﻭﻁﺭﻟﺍ ،ﺭﺎﺒﻐﻟﺍ ..

ﺦﻟﺍ ( ﺎﻬﻴﻭﺘﺤﺘ ﻲﺘﻟﺍ ﺕﺎﺒﻜﺭﻤﻟﺍ ﻰﻠﻋ ﻅﺎﻔﺤﻠﻟ ﻫﻭ

ﺫ ﺭﻴﺜﺄﺘ ﻱﺩﺎﻔﺘﻟ ﺍ

ﺎﻤﻴﺯﻨﺇ لﺜﻤ ﺕﺎﺒﻨﻟﺍ ﻲﻓ ﺓﺩﻭﺠﻭﻤﻟﺍ ﺕﺎﻤﻴﺯﻨﻹﺍ ﻑﻠﺘﺨﻤ ﺕ

Glycosidase

، Polyphenol-oxyda

ﺕﺎﻨﻭﻜﻴﻠﺠﺃ ﻭﺃ ﺔﻁﻴﺴﺒ ﺕﺍﺩﻴﺯﻭﺭﻴﺘﻴﺇ ﻰﻟﺇ ﺓﺩﻘﻌﻤﻟﺍ ﺕﺍﺩﻴﺯﻭﺭﻴﺘﻴﻹﺍ لﻭﺤﺘ ﻲﺘﻟﺍ

]

،15 21

.[

ﺏ - ﺍ ﻹ ﺹﻼﺨﺘﺴ :

ﻼﺨﺘﺴﺍ ﻡﺘ ﺹ

ﺏﺴﺤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﻁﻁﺨﻤﻟﺍ ﻲﻓ ﺔﺤﻀﻭﻤﻟﺍﻭ ﺔﻴﻟﺎﺘﻟﺍ ﺕﺍﻭﻁﺨﻟﺍ

:(4)

ﻌﺒ ﺏﺴﺎﻨﻤ ﺏﻴﺫﻤﺒ لﻤﺎﻌﺘ ،ﺎﻬﻨﻤ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺹﻼﺨﺘﺴﺍ ﺩﺍﺭﻤﻟﺍ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺀﺍﺯﺠﻷﺍ ﻥﺤﻁﻭ ﻑﻴﻔﺠﺘ ﺩ ﻡﺃ ﺏﻁﺭ ﺕﺎﺒﻨﻟﺍ ﺔﻟﺎﺤﻟ ﺎﻌﺒﺘ ﺍﺫﻫﻭ ﺎﻤﺍﺩﺨﺘﺴﺍ ﺕﺎﺒﻴﺫﻤﻟﺍ ﺭﺜﻜﺃ ﻲﻫ ﺔﻴﻟﻭﺤﻜﻟﺍ لﻴﻟﺎﺤﻤﻟﺍ ﺭﺒﺘﻌﺘﻭ ﺹﻼﺨﺘﺴﻼﻟ

لﻭﺤﻜﻟﺍ لﻤﻌﺘﺴﻨﻓ ،ﻑﺎﺠ )

ﻭﺃ لﻭﻨﺎﺜﻴﻤ ﺇ

لﻭﻨﺎﺜﻴ ( ﺎﻤﻬﻠﻴﻟﺎﺤﻤ ﻭﺃ ﺏﻁﺭﻟﺍ ﺕﺎﺒﻨﻟﺍ ﺔﻟﺎﺤ ﻲﻓ )

ﺔﺒﺴﻨﺒ 70%

ﻭﺃ

(80%

ﻑﺎﺠﻟﺍ ﺕﺎﺒﻨﻟﺍ ﺔﻟﺎﺤ ﻲﻓ .

ﺭﺨﺁ ﻰﻟﺇ ﻥﻴﺤ ﻥﻤ ﻙﻴﺭﺤﺘﻟﺍ ﻊﻤ ﺩﺤﺍﻭ ﻡﻭﻴ ﻥﻋ لﻘﺘﻻ ﺓﺩﻤﻟ ﺏﺴﺎﻨﻤﻟﺍ لﻭﻠﺤﻤﻟﺍ ﻲﻓ ﺔﻴﺘﺎﺒﻨﻟﺍ ﺀﺍﺯﺠﻷﺍ ﻊﻘﻨﺘ ﺎﻫﺩﻌﺒ ﺹﻠﺨﺘﺴﻤﻟﺍ ﺯﻴﻜﺭﺘ ﻡﺘﻴﻭ ﺢﺸﺭﻴ )

ﺔﺤﺎﺸﺭﻟﺍ (

ﺓﺩﻋ ﺔﻴﻠﻤﻌﻟﺍ ﺩﺎﻌﺘﻭ ﻑﺎﻔﺠﻟﺍ ﻰﺘﺤ ﺽﻔﺨﻨﻤ ﻁﻐﻀ ﺕﺤﺘ

ﻁﻟﺍ ﺕﺎﺒﻜﺭﻤﻟﺍ ﺏﻠﻏﺃ ﺹﻼﺨﺘﺴﺍ ﻥﻤ ﺩﻜﺄﺘﻟﺍ ﺔﻴﺎﻏ ﻰﻟﺇ ﺕﺍﺭﻤ ﻴﻌﻴﺒ

ﺔ

ﻲﻟﻭﺤﻜ لﻭﻠﺤﻤﺒ ﺹﻼﺨﺘﺴﺍ )

3 ( 70%

ﺯﻴﻜﺭﺘﻟﺍ ﻊﻤ ﺔﻴﻟﺎﺘﺘﻤ ﺕﺍﺭﻤ

ﺢﻴﺸﺭﺘﻟﺍ ﻊﻤ ﻥﺨﺎﺴﻟﺍ ﺀﺎﻤﻟﺍ ﻲﻓ ﺏﺍﺫﻴ

لﻭﺭﺘﺒﻟﺍ ﺭﺜﻴﺎﺒ ﺹﻼﺨﺘﺴﺍ

ﻡﺭﻭﻓﻭﺭﻭﻠﻜﻟﺎﺒ ﺹﻼﺨﺘﺴﺍ

ﺹﻼﺨﺘﺴﻻﺍ لﻴﺜﻴﻻﺍ ﺕﻼﺨﺒ

ﻻﺍ ﻱﺩﺎﻌﻟﺍ لﻭﻨﺎﺘﻭﺒﻟﺎﺒ ﺹﻼﺨﺘﺴ

ﻁﻁﺨﻤﻟﺍ :1

ﺘﻤﻟﺍ ﺕﺍﻭﻁﺨﻟﺍ ﺹﻼﺨﺘﺴﻹﺍ ﺔﻴﻠﻤﻋ ﻲﻓ ﺔﻌﺒ

ﺴﻣ فﺎﺠﻟا تﺎﺒﻨﻟا قﻮﺤ

فﺎﺠﻟا ﻲﻟﻮﺤﻜﻟا ﺺﻠﺨﺘﺴﻤﻟا

لوﺮﺘﺒﻟا ﺮﺜﯾا ﺺﻠﺨﺘﺴﻣ ﻲﺋﺎﻤﻟا رﻮﻄﻟا

لﻮﻧﺎﺗﻮﺒﻟا ﺺﻠﺨﺘﺴﻣ

ﻞﯿﺘﯾﻻا تﻼﺧ ﺺﻠﺨﺘﺴﻣ

ﻲﺋﺎﻤﻟا رﻮﻄﻟا ﺔﯿﻘﺑ

ﻲﺋﺎﻤﻟا رﻮﻄﻟا

ﻲﻣرﻮﻓورﻮﻠﻜﻟا ﺺﻠﺨﺘﺴﻤﻟا ﻲﺋﺎﻤﻟا رﻮﻄﻟا

ﻲﺋﺎﻤﻟا ﺺﻠﺨﺘﺴﻤﻟا

ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ ﺔﻴﻘﻨﺘ ﻭ لﺼﻓ -3-V :

ﺃ - لﺼﻔﻟﺍ :

ﺔﻨﺴ ﻲﻓ ﻡﺘ 1903

ﻲﺴﻭﺭﻟﺍ ﻡﻟﺎﻌﻟﺍ ﻑﺭﻁ ﻥﻤ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜﻟﺍ ﻑﺎﺸﺘﻜﺍ

TWEST

ﻲﻫﻭ ﺔﻴﻠﻴﻠﺤﺘ ﺔﻘﻴﺭﻁ

ﺎﻨﻭﻜﻤ لﺼﻔﻟ ﺔﻴﺭﻴﻀﺤﺘﻭ ﺕ

ﺎﻤ ﻁﻴﻠﺨ .

ﺔﻴﺴﻴﺌﺭ ﻉﺍﻭﻨﺃ ﺔﺜﻼﺜ ﻰﻟﺇ ﻲﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜﻟﺍ لﺼﻔﻟﺍ ﺕﺎﻴﻨﻘﺘ ﻡﺴﻘﺘﻭ :

- ﺩﻭﻤﻌﻟﺍ ﺎﻴﻓﺭﻏﻭﺘﺎﻤﻭﺭﻜ (CC)

- ﺔﻘﻴﻗﺭﻟﺍ ﺔﻘﺒﻁﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ

(CCM)

- ﻕﺭﻭﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ

(CP)

ﺃ - -1 ﺤﺘﻟﺍ ﺔﻘﻴﻗﺭﻟﺍ ﺔﻘﺒﻁﻟﺍ ﺎﻴﻓﺍﺭﻏﻭﺘﺎﻤﻭﺭﻜ ﺔﻴﺭﻴﻀ

:

ﺩﺎﻌﺒﺃ ﺕﺍﺫ ﺢﺌﺍﺭﺸ ﺔﻴﻨﻘﺘﻟﺍ ﻩﺫﻫ ﻲﻓ لﻤﻌﺘﺴﻨ )

×20

ﻡﺴ 20

( ﺔﺒﻠﺼﻟﺍ ﺔﻤﺎﻋﺩﻟﺍ ﻥﻤ ﺔﻘﻴﻗﺭ ﺔﻘﺒﻁ ﺭﻀﺤﺘ ﺙﻴﺤ

ﺩﺩﻌﺘﻤ ﻥﻋ ﺓﺭﺎﺒﻋ ﻥﻭﻜﺘ ﺢﺌﺍﺭﺸﻟﺍ ﻩﺫﻫ ﻰﻠﻋ ﺯﻭﻠﻴﻠﻴﺴﻟﺍ ﻭﺃ لﺠﺎﻜﻴﻠﻴﺴﻟﺍ ﻭﺃ ﺩﻴﻤﻷﺍ

.

ﺩﻌﺒ ﻰﻠﻋ ﺔﺤﻴﺭﺸﻟﺍ لﻭﻁ ﻰﻠﻋ ﺏﻜﺭﻤﻟﺍ ﻊﻀﻭﻴ )

2-1.5

ﻡﺴ ( ﻊﻀﻭﺘ ﻡﺘ ﻑﺠﺘ ﺎﻬﻜﺭﺘﻨ ﺔﻴﺭﻌﺸ ﺔﺼﺎﻤ ﺔﻁﺴﺍﻭﺒ

ﻤﻟﺍ ﻲﻓ ﺔﻟﺎﺤ ﻲﻓ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﺼﻔﻟ ﺔﻠﻤﻌﺘﺴﻤﻟﺍ ﺕﺎﺼﻠﻤﻤﻟﺍ ﻥﻤﻭ ،ﺹﻠﻤ ﺢﺌﺍﺭﺸ

ﻲﻠﻴﺎﻤ ﺩﻴﻤﻷﺍ ﺩﺩﻌﺘﻤ :

S1: (4 / 3 / 3): Toluene / Méthyléthylcetone / Méthanol

S₂ :( 60 / 26 /7 / 7): Toluene / Ether de petrol / Méthyléthylcetone / Acetylacetone

S3: (13 / 3 / 3 /1): Eau / Méthyléthylcetone / Méthanol / Acetylacetone

S4: (30 / 15 / 10 / 5): Eau / Méthyléthylcetone / Méthanol / Acetylacetone

ﻭ ) لﻭﺩﺠﻟﺍ (2

ﻰﻠﻋ ﺕﺍﺩﻴﻨﻭﻓﻼﻔﻟﺍ لﺼﻓ ﻲﻓ ﺔﻌﺌﺎﺸﻟﺍ ﺔﻤﻅﻨﻷﺍ ﺽﻌﺒ لﻤﺸﻴ ﺢﺌﺍﺭﺸ

ﺩﻴﻤﻷﺍ ﺩﺩﻌﺘﻤ

لﻭﺩﺠﻟﺍ :2

لﺼﻔﻟﺍ ﺔﻤﻅﻨﺃ ﺽﻌﺒ

ﻡﺌﻼﻤﻟﺍ ﻡﺎﻅﻨﻟﺍ

ﻉﻭﻨ ﻭﻓﻼﻔﻟﺍ ﺕﺍﺩﻴﻨ

H2O-MeOH-MEC-Acetylacetone (13/3/3/1) / (30/15/10/5) H₂O-n-BuOH-Acetone-Dioxane(70/15/10/5)

ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠﻟﺍ

MeOH-AcOH-H2O (18/1/1)

H2O-EtOH-n-BuOH-AcOH (50/25/20/2) / (75/15/10/2)

ﺕﺍﺩﻴﺯﻭﻜﻴﻠﺠﻟﺍ ﺕﺎﻨﻭﻜﻴﻠﺠﻻﺍﻭ

ﺔﻴﺒﻁﻘﻟﺍ

(polyhydroxylées)

Toluène.-Héxane-MEC-MeOH (30/90/2/1.5) / (60/30/10/5) Toluène-MEC-MeOH(4/3/3)

Toluène-Ether de petrol-MEC-MeOH(60/26/10/10)

ﺔﻴﺒﻁﻘﻟﺍ ﺭﻴﻏ ﺕﺎﻨﻭﻜﻴﻠﺠﻷﺍ

) لﻴﺴﻜﻭﺘﻴﻤﻟﺍ ﺓﺩﺩﻌﺘﻤ (