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[PDF] Top 20 Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

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Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

... considered to be major organic osmolytes, play an important role in cell volume ...into the extracellular space, compensating for intracellular hypertonicity, thus preventing cell swelling and ... Voir le document complet

13

Increased extracellular brain glutamate in acute liver failure: decreased uptake or increased release?

Increased extracellular brain glutamate in acute liver failure: decreased uptake or increased release?

... increased release? Metabolic Brain Disease, 17(4), ...demonstrating the possible mechanisms involved in the development of HE and brain edema ... Voir le document complet

13

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats

... aim of this study was to induce oxidative stress in hyperammonaemic PCA rats by targeting and diminishing the antioxidant GSH, a tripeptide formed of glutamate, cysteine and ... Voir le document complet

10

Brain-gut interactions in inflammatory bowel disease.

Brain-gut interactions in inflammatory bowel disease.

... Effect of early-life events on colitis: The HPA axis is programmed by early life events and neonatal inflammatory stimuli exert long-term changes in HPA activity and immune regulation ... Voir le document complet

53

Increase brain lactate in hepatic encephalopathy: Cause or consequence?

Increase brain lactate in hepatic encephalopathy: Cause or consequence?

... ROM THE BLOOD The same way hyperammonemia leads to increased brain ammonia, it is often debated whether hyperlactataemia leads to an increase in cerebral ... Voir le document complet

10

AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats

AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats

... related to ammonia is represented by astrocyte swelling, which leads to brain ...5 Brain edema, a common finding in patients with acute liver failure, 6 ... Voir le document complet

14

Brain edema : a valid endpoint for measuring hepatic encephalopathy?

Brain edema : a valid endpoint for measuring hepatic encephalopathy?

... Techniques to measure brain edema It is evident that the development of intracranial hypertension is associated with brain edema in ALF, ... Voir le document complet

22

Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure

Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure

... Induction of PTBR expression in the brain is a consistent finding associated with both acute and chronic liver ...failure. Increased densities of ... Voir le document complet

9

Mild hypothermia prevents cerebral edema and CSF lactate accumulation in acute liver failure

Mild hypothermia prevents cerebral edema and CSF lactate accumulation in acute liver failure

... brain edema (Swain et ...toxicity is (directly or indirectly) the cause of brain edema in this model of ALF (Cordoba and Blei, ...from the present ... Voir le document complet

10

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

... water in and out of the ...many of which are present in the brain. In particular, Aqp-4 has demonstrated to be highly expressed in astrocytes compared ... Voir le document complet

20

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

... from the ailing liver is a major source of ROS ...increase in XO activity was found in BDL rats, allopurinol, a XO inhibitor, was investigated as an antioxidant (oxidant ... Voir le document complet

16

What is the role of relatives in treatment choice of patients with advanced chronic kidney disease?

What is the role of relatives in treatment choice of patients with advanced chronic kidney disease?

... renal disease patients on dialysis modality ...(2010). The views of patients and carers in treatment decision making for chronic kidney disease: systematic review and thematic ... Voir le document complet

3

Development of adenocarcinoma in chronic fistula in Crohn's disease

Development of adenocarcinoma in chronic fistula in Crohn's disease

... narcosis with a new dilatation of the rectum and ...found in the ...ulcerated in its center at the place of the fistula above the ...tomography ... Voir le document complet

4

Relating pessimistic memory predictions to Alzheimer’s disease brain structure

Relating pessimistic memory predictions to Alzheimer’s disease brain structure

... on the one hand and hippocampus and lateral prefrontal cortex (LPFC) on the other ...retrieval of recent episodic memories in AD patients might be related to disconnection within a wide ... Voir le document complet

38

Warfarin-induced vitamin K deficiency is associated with cognitive and behavioral perturbations, and alterations in brain sphingolipids in rats

Warfarin-induced vitamin K deficiency is associated with cognitive and behavioral perturbations, and alterations in brain sphingolipids in rats

... consisted of a large, circular, metal pool (diameter: 150 cm) filled approximately half-way (30 cm) with 22˚C water containing a fixed invisible platform (10 cm 2 ) which was submerged below the ... Voir le document complet

109

Brain edema and intracranial hypertension in fulminant hepatic failure: Pathophysiology and management

Brain edema and intracranial hypertension in fulminant hepatic failure: Pathophysiology and management

... hypertension is a major cause of morbidity and mortality of patients suffering from fulminant hepatic ...failure. The etiology of this intracranial hypertension is not fully ... Voir le document complet

8

SERPINA1 Z allele is associated with cystic fibrosis liver disease

SERPINA1 Z allele is associated with cystic fibrosis liver disease

... Methods: The associations of SERPINA1 Z (rs28929474) and S (rs17580) alleles with age at CFLD onset and the development of CFLD-related complications (severe liver ... Voir le document complet

25

Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury

Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury

... ted with acute brain injury to the neuroscience ICU of our hospital; screening was performed within 3 days after ...for the absence of the ability to follow ... Voir le document complet

10

Liver mitochondrial function in ZDF rats during the early stages of diabetes disease

Liver mitochondrial function in ZDF rats during the early stages of diabetes disease

... Determination of mitochondrial membrane potential by flow cytometry Isolated mitochondria (1 mg mL 1 ) were incubated with different substrates (same conditions as for measurement of ROS production) ... Voir le document complet

12

Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain

Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain

... One of the main components of senile plaques in Alzheimer’s disease (AD)-affected brain is the Aβ peptide species harboring a pyroglutamate at position three ... Voir le document complet

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