[PDF] Top 20 Stem cells and the circadian clock

... of the genes expressed in adipose tissue exhibit circadian oscillations in mice ( Ptitsyn et ...of the circadian clock in the regulation of adipose tissue metabolism and ... Voir le document complet

... 1. STEM CELLS During embryogenesis, a single fertilized oocyte gives rise to a multicellular organism whose cells and tissues have adopted differentiated characteristics or fates to perform ... Voir le document complet

... plants and animals, have a circadian clock present in each cell, generally in the form of a self-sustained genetic oscillator entrained by the day/night cycle through various ...This ... Voir le document complet

... Abstract Circadian clocks drive biological rhythms with a period of approximately 24 hours and keep in time with the outside world through daily resetting by environmental ...in the ... Voir le document complet

... Glioma Stem Cells Take Different Routes to Reach the Subventricular Zone In non-tumoral brains, white matter tracts can act as a guide, or a motorway, for the migration of NSCs or glial ... Voir le document complet

... a circadian clock period close to 24 hours regardless of the medium ...use the circadian clock model of Relogio et ...on the am- plitude and phases of the ... Voir le document complet

... 110 and humans, a master clock in the brain synchronizes the circadian clocks in other cells of the body, and only the master clock is able to sustain ... Voir le document complet

... compared the quantitative representation of shRNAs in the input and leukemic bone marrow samples, and observed strong concordance between biological replicates (Figures 1A and ...AML ... Voir le document complet

... Abstract The cell division cycle and the circadian clock are two fundamental processes of cellular con- trol that generate cyclic patterns of gene activation and protein ... Voir le document complet

... between clock and feeding cycles Feeding cycles are one of the most prominent zeitgeber for peripheral tissues [4,5,19,20], and investigations have uncovered the existence of ... Voir le document complet

... RA and the Effect of MSCs As previously mentioned, in RA pathogenesis, innate immune cells have an important role not only by directly inducing inflammation and bone erosion but also by ... Voir le document complet

... potential and its variation with the number of cells in a cluster We next decided to investigate a more comprehensive measure of ...Since the process of self‐renewal consists of cell division  ... Voir le document complet

... to the chromosome region 7q31 and encodes a transmembrane tyrosine kinase recep- tor closely related in sequence to the insulin ...by cells of epithelial or endothelial origin. The ... Voir le document complet

... genetic and epigenetic alterations. Similarities and dissimilarities between normal stem cells and cancer stem cells open three ...stemness the same in cancers ... Voir le document complet

... stromal cells, Glottic cancer, Bone marrow Main text We have read with great interest the article by Hertegård et ...stromal cells - first phase I / II human clinical study” [ 1 ...congratulate ... Voir le document complet

... strength, and regenerative capacity. Decreased muscle stem cell (MuSC) number and impaired function might underlie the aging-related muscle wasting and impaired regenerative ...yet, ... Voir le document complet

... balance and the c-myc / Lin28 / let-7 axis (A) Purified RNA from ...mESCs and E14 mESCs cultured in either serum+LIF or 2i +LIF conditions was extracted and reverse-transcribed with TaqMan ... Voir le document complet

... cancer stem cells to triple-negative breast cancers, a poor prognosis form of breast cancer in young ...that the numbers of breast cancer stem cells that were inversely correlated to ... Voir le document complet

... | the cytoplasm to the nucleus. Here, CLOCK is phosphorylated at Serine 440-441-446, and this post-translational modification promotes the transactivation mediated by CLOCK: ... Voir le document complet

... DNA and histone modification enzymes following metabolic changes, and con- versely, epigenetic mechanisms can regulate the cellular metab- olome through modulating metabolic gene ...understanding ... Voir le document complet