[PDF] Top 20 Altered adipose tissue metabolism in offspring of dietary obese rat dam

... mechanisms of developmental programming, we analysed the effects of maternal overnutrition and of postnatal high-fat feeding on adipose tissue metabolism in the ...changes ... Voir le document complet

... risk of metabolic disease in ...effect of n-6 PUFA status on adiposity are not all yet ...role in neonatal programming by imprinting gene expression [ 18 ...physiology, metabolism and ... Voir le document complet

... number of different pathways to obesity with different metabolic outcomes are ...undernutrition in rats leads to increased fat deposition in ...form of obesity is metabolically distinct from ... Voir le document complet

... Supplemental Informations Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue Delphine Duteil, Milica Tosic, Franziska Lausecker, Hatice Z. Nenseth, Judith M. Müller, Sylvia Urban, ... Voir le document complet

... In addition to the canonical LMNA mutations observed in patients with the typical form of FPLD2, several LMNA mutations have been reported in patients with atypical forms of ... Voir le document complet

... is of the highest in- terest for developing new strategies to counteract ...dated. In this study, we show that the histone demethylase Lsd1 plays a key role in the maintenance of brown ... Voir le document complet

... area of the SVF in tissue seticons, we used image ...magnification of sections stained with hematoxylin and eosin. In each image, a global threshold was computed by using Otsu’s method ... Voir le document complet

... of biological replicates for each ...reproducibility of expression across samples, with 1249 of them having an FPKM-UQ higher than ...0.1 in at least 10 of the 16 samples in the ... Voir le document complet

... ability of APs present in these cultures by replacing the EGM2 medium by αMEM-2% FCS supplemented with different adipogenic ...differentiation of APs into mature adipocytes, as demonstrated by the ... Voir le document complet

... differentiation of adipocytes from progenitor cells ( Hammarstedt et ...alteration in the dynamic of epiWAT expansion in Rab4b Tcell KO mice resulted from a reduction in adipocyte ... Voir le document complet

... mesenteric adipose tissue, Crohn’s disease, animal model U lcerative colitis and Crohn’s disease (CD) are the most common forms of inflammatory bowel disease ...hallmarks of CD are chronicity ... Voir le document complet

... amounts of angiogenin, which belongs to the family of pro-angiogenic ...proliferation of cultured endothelial cells, and also serves as an adhesion molecule for endothelial ...formation of ... Voir le document complet

... morphology of mature adipocytes in both SLA and NSLA ...Immunostaining of Perilipin, a specific protein surrounding the lipid droplets, revealed a smaller size of lipid droplets in the ... Voir le document complet

... mg of frozen VAT was fixed in ...concentration of 0.125 mM of glycine and incubated for 5 ...sample in cell lysis buffer the nucleus phase was pelleted and then suspended in ... Voir le document complet

... out in two steps: 10 minutes at 25°C followed by 2 hours at ...gene of in- terest (Table S8). For each tissue, samples were quantified in duplicate and normalized to YWHAZ and ... Voir le document complet

... subcutaneous adipose tissue. Conversely, no significant change in the visceral one was observed, however, the ratio of pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages has ... Voir le document complet

... Studies in Vitro: Rat liver microsomes: Incubation of rat liver microsomes with 100 µM fluindione showed formation of a major metabolite identical to M2 with a m/z = ... Voir le document complet

... consequences of adverse events during perinatal period on intestinal barrier functionality and immune response in different model challenged with stress, chemical or infections within the framework ... Voir le document complet

... ABSTRACT In obese humans CT imaging is a validated method for follow up studies of adipose tissue distribution and quantification of visceral and subcutaneous ...methods ... Voir le document complet

... concentration, [Ag] is the free antigen concentration, D is the diffusion coefficient in tumor tissue, V 2 is the Laplacian, kon is the binding rate, E is the void volume, kff i[r] ... Voir le document complet