[PDF] Top 20 Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
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Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
... in the expression of early-response genes and maintaining synaptic ...understand the connections between activity-induced DSBs, Topo IIβ, and early- ... Voir le document complet
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Coupling DNA Damage and Repair: an Essential Safeguard during Programmed DNA Double-Strand Breaks?
... These activity-induced prDSBs occur primarily in early response genes and are introduced by the topoisomerase II ...particular the case in the response ... Voir le document complet
12
Activity-regulated genes as mediators of neural circuit plasticity
... Discovery of Activity-Regulated Genes The first genes found to be activity-regulated in neurons were initially identified in mitotic cells as responsive to extracellular cues ... Voir le document complet
34
Neuronal Activity Propagation in the Brain: From Neuronal Avalanches to Synfire Chains and Gamma Oscillations
... oscillation of up- and down ...spiking activity of in vitro experiments and found robust evidence for a critical state during large-scale synchronization of spiking ...asynchronous ... Voir le document complet
183
Temporal and spatial expression of genes involved in DNA methylation during reproductive development of sexual and apomictic Eragrostis curvula
... within genes could be more permissive in apomict ovules and, therefore, supports the notion that RdDM is involved in the establishment of gene expression patterns governing the ... Voir le document complet
12
JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
... JMJD6 expression is required for NHEJ. We next tested whether the effect of JMJD6 on DNA damage signaling and repair could be direct by assessing the recruitment of GFP-tagged ... Voir le document complet
32
[Bacterial infections as seen from the eukaryotic genome: DNA double strand breaks, inflammation and cancer].
... d’un stress génotoxique provoquant des cassures double-brin de l’ADN, l’histone H2AX est phosphorylée sur la sérine en position 139 ( γ H2AX) en quelques minutes. De nombreuses molécules γ H2AX s’accumulent sur des ... Voir le document complet
8
Expression of genes of the Pho regulon is altered in Streptomyces coelicolor
... SC, the difference of expression of some PhoP targets between the original strain and its phoP mutant might have been too small to allow the detection of all PhoP ... Voir le document complet
22
Bayesian Modelling of Induced Responses and Neuronal Rhythms
... cortical activity during cognitive ...interrogate the canonical microcircuit hypothesis, which predicts that neurons in distinct cortical layers contribute to distinct computations (Bastos et ... Voir le document complet
15
Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats
... drive the addiction cycle ( Koob and Le Moal, 2001; Sommer and Spanagel, 2013 ...investigated the effects of alcohol exposure, followed or not by a withdrawal periods, on the expression ... Voir le document complet
12
Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes
... stimulate the long-term replication of a plasmid carrying the oriP replicator from EBV (Figure ...believe the mechanism at play is the early and more pronounced transcriptional ... Voir le document complet
14
Local magnetic detection and stimulation of neuronal activity
... Local-scale neuronal sensing ...neuroscience The previous large-scale imaging techniques provide meaningful data to map key func- tional regions of the ...bridge the gap between ... Voir le document complet
193
Dysregulation of peripheral expression of the YWHA genes during conversion to psychosis
... Levels of the current antipsychotic treatments were transformed into chlorpromazine equivalent doses that were used as a covariate in the regression ...for the computation of ... Voir le document complet
10
UV-induced DNA Damage: The Role of Electronic Excited States
... INTRODUCTION The effects resulting from the DNA damage induced by UV radiation (carcinogenic mutations, cell lethality, ...efforts of the photobiology community.Considerable ... Voir le document complet
27
Differential Expression of Genes and DNA Methylation associated with Prenatal Protein Undernutrition by Albumen Removal in an avian model
... in the chicken model of prenatal protein undernutrition by albumen ...Introduction of such persistent alterations in phenotype suggests stable changes in gene ...screening of the ... Voir le document complet
12
Ku counteracts mobilization of PARP1 and MRN inchromatin damaged with DNA double-strand breaks
... least DNA end-binding and bridging, ends-processing and final ligation ...in the absence of Ku, PARP1 can achieve synapsis (52) and PARP1/XRCC1-LIG3 can promote end-joining ...implicated the ... Voir le document complet
16
Drought-induced acclimation of DNA-hypomethylated poplars
... Divergence of taxa with life-history traits that favour large effective population sizes and retention of ancestral polymorphisms ...in the ecosystem, and wind pollination) often coincide with models ... Voir le document complet
135
ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
... motes DNA-PKcs phosphorylation at Ser-2056 that is sen- sitive to DNA-PKi, as expected for an autophosphorylation site (Figure 4 ...B-E). The boost of DNA-PKcs Ser-2056 phosphorylation ... Voir le document complet
15
Spatio-Temporal Linear Response of Spiking Neuronal Network Models
... study the impact of a weak time- dependent external stimulus on the collective statistics of spiking responses in neuronal ...extend the current knowledge, assessing the ... Voir le document complet
2
Human herpes virus-6 induced changes in the expression and activity of the E2F family transcription factors in human cells
... By using Western blots and electromobility shift assays (EMSA), we compared the expression and DNA-binding activities of the E2F farnily members between the virns-infected and mock-infec[r] ... Voir le document complet
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