BREAST CARCINOMA
The Role of Stroma in Breast Carcinoma Growth in Vivo
... in breast carcinoma form primarily by differentiation from fibroblasts, but they also may be derived from vascular smooth muscle cells, and occasionally from ...In breast cancer, the myofibroblasts ...
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Lymph node positivity in different early breast carcinoma phenotypes: a predictive model
... Conclusions We reported a reliable predictive model of LN positivity according to different early breast carcinoma phenotypes in a large cohort. The determination of the risk of positive axillary LN can ...
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Alterations in Glycopeptides Associated with Herceptin Treatment of Human Breast Carcinoma MCF-7 and T-Lymphoblastoid Cells
... EXPERIMENTAL PROCEDURES Cell Lines and Three-Dimensional Culture Conditions—The human breast carcinoma MCF-7 cell lines were obtained from the American Type Cells Collection, Manassas, VA. T-lymphoblastic ...
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N-Glycomic changes in human breast carcinoma MCF-7 and T-Lymphoblastoid cells after treatment with Herceptin and Herceptin/Lipoplex
... human breast MCF-7 carcinoma and T-lymphoblastoid CEM cells s were studied here and compared with profiles after treatment with Herceptin alone or in combination with Lipofectamine mixed with plasmid DNA to ...
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CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways.
... particular breast, lung, or ovarian carcinoma cell lines [31- ...lymphocytes, breast carcinoma cell survival is affected by CD40L in a complex manner: soluble CD40 ligand has been reported to ...
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First French Pilot Quality Assessment of the EndoPredict Test for Early Luminal Breast Carcinoma
... the breast cancer samples. The mean EndoPredict (EP) score for the breast cancer sample was ...test. Breast carcinoma is the most frequent cancer diagnosed in ...that breast cancers are ...
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Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma.
... primary breast tumors excised from 97 women at Centre René Huguenin from 1980 to ...postmenopausal breast carcinoma; ER α-positive as determined at the protein level by biochemical methods ...
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Combined treatment of human MCF-7 breast carcinoma with antibody, cationic lipid and hyaluronic acid using ex vivo assays
... The other findings of the present study suggest that HA appears to be a growth-inhibitory agent in breast carcinoma cells due to binding to CD44 receptors. HA is used in clinical treatment due to its unique ...
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DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells.
... Basal-like breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal ...in breast cancer, and its overexpression ...
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Snail and slug play distinct roles during breast carcinoma progression.
... in breast carcinomas were found to be distributed along a wide range around normal breast level, encompassing two orders of ...any carcinoma histological subtype, suggesting Slug and Snail role ...
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DDR1 and MT1-MMP expression are determinant for triggering BIK-mediated apoptosis by 3D type I collagen matrix in invasive basal-like breast carcinoma cells
... Saby C, et al. DDR1 and MT1-MMP expression levels are determinant for triggering BIK-mediated apoptosis by 3D type I collagen matrix in invasive basal-like breast carcinoma cells. Front. Pharmacol. 10:462. ...
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Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
... of breast tumor DNA and commercial pooled human normal genomic DNAs (Promega, Madison, WI) was digested with 5 μg of AluI (50 units) and 5 ml of RsaI (50 units) (Promega, Madison, WI) and labeled by random priming ...
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Contribution of adipose stem cells from obese subjects to hepato-or breast-carcinoma tumorogenesis, through promotion of Th17 cells
... hepatocellular carcinoma (HCC) treatment, we carried out proof-of-concept experiments that showed in two cell lines enhanced radiosensitivity when irradiated in the presence of the PARP inhibitor Veliparib ...
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en fr Insight into sensitivity mechanisms to antiandrogens in molecular apocrine breast carcinoma Contribution à l’étude des mécanismes de sensibilité aux traitements antiandrogènes dans les cancers du sein moléculaires apocrines
... 175 transcriptional studies for identifying AR-positive ER-negative breast cancer (1,2) (supplementary material 3). RNA labeling and hybridization reactions were performed according to the manufacturer’s ...
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Percutaneous stereotactic en bloc excision of nonpalpable breast carcinoma: a step in the direction of supraconservative surgery
... for breast cancer. So-called conservative breast surgery, ...with breast surgery, moving towards the concept of prognostic evaluation; for this the quality of the specimen takes priority over the ...
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EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma
... negative breast cancer ...526 breast cancer patients that was collected over the last 30 years (Supplementary Table ...in breast cancer patient tissues is associated with high breast cancer ...
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Monitoring of 3D breast carcinoma cell culture using proton magnetic resonance imaging
... 14 ml/min. The pH in the extracapillary space was maintained at between 6.8 and 7.0 throughout the experiments. The perfusion medium was changed weekly when the glucose level reached 2 g/l measured by glucometer. ...
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Identification of a three-gene expression signature of poor-prognosis breast carcinoma.
... of breast cancer, but also to the fact that breast tumors consist of many different cell types – not just tumoral epithelial cells, but also addi- tional epithelial cell types, stromal cells, endothelial ...
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Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression.
... derived hormones, that the ducts elongate and differentiate into terminal end buds (TEBs). Estrogens are responsible for epithelial cell proliferation, growth of mesenchyme and adipose tissue vascularization. ...
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Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno- Oncology Biomarker Working Group on Breast Cancer
... invasive breast cancer, TILs in breast CIS are first evaluated on H & E-stained sections of formalin-fixed, paraffin-embedded ...micro-invasive carcinoma [43] and 3) CIS with an invasive ...
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