Haut PDF Role of Sirtuin-1 in the pathogenesis of hypertension in spontaneously hypertensive rats : molecular mechanisms
Role of Sirtuin-1 in the pathogenesis of hypertension in spontaneously hypertensive rats : molecular mechanisms
... Abstract Sirtuin-1 (Sirt-1), class III histone deacetylase, has been shown to be overexpressed in hearts from spontaneously hypertensive rats ...expression of ...
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Effect of knockdown of Giα proteins using antisense oligodeoxynucleotides encapsulated in cationic liposomes on the development of hypertension in spontaneously hypertensive rats
... family of guanosine triphosphate (GTP) binding proteins that play a crucial regulatory role as transducers in a variety of cell signaling ...composed of three distinct subunits; α, β, ...
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The Effect of Resveratrol on the Hyperproliferation of Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats : Molecular Mechanisms
... to the hyperproliferation and hypertrophy of vascular smooth muscle cells (VSMCs) is central in the development of ...from spontaneously hypertensive rats (SHR) ...
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Contribution of tachykinin and kinin receptors in central autonomic control of blood pressure and behavioural activity in hypertensive rats
... antagonist of the B1R in all species tested (rat, mouse, rabbit and human) and is orally ...active. The selectivity for B1R versus B2R was in the range of 500- to ...
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Molecular mechanisms of Evening Complex activity in Arabidopsis
... occur in a rhythmic manner over a 24-h cycle ...even in the absence of light/dark cues due to internal re- peating oscillations of core clock genes that in turn modulate gene ...
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Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure
... supporting the idea that formation of the plaque is asso- ciated with early adventitial ...involvement in vascular remodeling, even in the pathogenesis of intimal ...
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A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.: p130Cas Over-Expression in Pulmonary Hypertension
... activation of EGF-R, FGF-R and PDGF-R pathways have been proven to be involved in the development of several diseases including cancer and PAH(4-8, 23, ...Inhibition of these specific ...
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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats Short Title: CXCL12 neutraligands in severe PH in the rat
... Wistar rats were injected with monocrotaline or were subjected to SU5416 followed by 3-week Hypoxia to induce severe ...SuHx rats were randomized to receive CXCL12 neutraligands chalcone 4 or LIT-927 (100 ...
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Molecular mechanisms in the activation of Abscisic acid receptor PYR1
... to the ECD analysis, nearest inter-molecular neighbors identified by Accelrys VS with a 5 A ˚ cutoff have also been compared for the initial PYR1-ABA-HAB1 complex and the recovered ...
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en fr New insights in the pathogenesis of pulmonary arterial hypertension Nouveau regard sur la physiopathologie de l’hypertension artérielle pulmonaire
... : Hypertension pulmonaire, remodelage vasculaire pulmonaire, cellule musculaire lisse, cible ...arterial hypertension (PAH) is a severe and incurable cardiopulmonary ...from the past 10 years ...
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Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure
... and the temporal resolution of ammonia, ROS, and BE were evaluated only in BDL ...found in PCA and BDL rats, both significantly higher compared to their respective sham-operated ...
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Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats
... arterial hypertension (PAH) is a rare and severe disease in which pressure elevation in the pulmonary arteries (PA) leads to right heart failure and ...and the effects of ...
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IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats
... death in the striatum and alters glycemia. (A) Images of representative brain sections stained for COX histochemistry of control rats (Ctr) and rats chronically treated with 3NP ...
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The role of interferon Beta (IFN-β) in the pathogenesis of infection caused by streptococcus suis serotype 2
... response of the body to ensure removal of detrimental stimuli, as well as a healing process for repairing damaged tissue ...sensing the presence of microorganisms by recognizing ...
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The role of several heat transfer mechanisms on the enhancement of thermal conductivity in nanofluids
... transfer mechanisms in nanofluids, such as formation of a nano-liquid-layer around the nanoparticles (liquid layering) [13-16], particles clustering [17-20] and Brownian motion of ...
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Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects
... networks. In this context, most cancer cells predominantly undergo high rate of glycolysis, up to 200 times higher than those of their normal tissues even in the absence of ...
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The molecular mechanisms of reaction wood induction
... (2003) The Arabidopsis 1019 CDPK-SnRK superfamily of protein ...at the wall: cell wall receptors and 1021 ...analysis of functional genes 1023 associated with cell wall biosynthesis and ...
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Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension
... conducted in vitro highlighted the modulation of CD39 by various ...cytokines. In VSMCs specifically, we report a decrease in CD39 mRNA expression in response to proinflammatory ...
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The Role of Aryl Hydrocarbon Receptor (AHR) and AHR-Interacting Protein (AIP) in the Pathogenesis of Pituitary Adenomas
... activator of AhR, able to stimulate its translocation to the nucleus simi- larly to dioxin, although in this case nuclear AhR does not appear to dimerize with ARNT or induce CYP1A transcription, but ...
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PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1.
... responses. The usual scheme of activation of αβ T cells relies on positive signals given by peptide antigens presented by HLA class I or ...Among the negative signaling molecules, those ...
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