[PDF] Top 20 Mnk1 kinase activity is required for abscission.
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Mnk1 kinase activity is required for abscission.
... both MNK1 and MNK2, we investigated whether the appearance of multinucleated cells was due to MNK1 inhibition by using a dominant-negative approach, and compared the effect of expressing either active ... Voir le document complet
10
RIP2 filament formation is required for NOD2 dependent NF-κB signalling
... the kinase domain (RIP2K) is on the ...of kinase dimerization with auto-phosphorylation of the activa- tion ...promotes kinase dimerization, by increasing the local RIP2 con- ...the ... Voir le document complet
20
Htt is a repressor of Abl activity required for APP-induced axonal growth
... hypothesis is unlikely for the MB phenotype described here since qRT-PCR analysis of third instar brains did not reveal a significant differences in Abl mRNA levels between htt int /+ and control ...Abl ... Voir le document complet
26
14-3-3zeta is required for PKA-dependent lipolysis in mature adipocytes
... levels for Adrb1 and Adrb2, a significant reduction in mRNA levels of Adrb3, which is mainly expressed in adipocytes [179], was observed (Figure ...cyclase activity was affected by 14-3-3ζ depletion, ... Voir le document complet
91
The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin
... ICL is nondenaturable and displays delayed migration (upper band) compared to the unaffected denatured single-stranded DNA (lower ...image is representative of those from four independent ...ICL ... Voir le document complet
15
Aurora A kinase activity is required to maintain an active spindle assembly checkpoint during prometaphase
... Live cell imaging MLN8237 approach: HeLa cell line expressing Tubulin-GFP (Reboutier et al., 2013) was grown on Zeiss High resolution cover sleeps for 24h then synchronized as describe in Fig. 1A. Video ... Voir le document complet
39
Sperm SPACA6 protein is required for mammalian Sperm-Egg Adhesion/Fusion
... Tssk6 is required for Izumo relocalization and gamete fusion in the ...Kalfa for their participation in this work during their ...samples required for this study were provided by ... Voir le document complet
16
Auxin Perception Is Required for Arbuscule Development in Arbuscular Mycorrhizal Symbiosis
... reported for Medicago truncatula, maize (Zea mays), and soybean (Glycine max; Ludwig-Müller et ...which is deficient in auto- regulation of nodulation, suggesting that IAA might play a role in the ... Voir le document complet
14
Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons
... a for- ward genetic screen to identify mutations that lead to the loss of habenular ...Tcf7l2 is expressed in dHb neurons on both left and right as they initiate ...signaling is enhanced [ 13 ] and ... Voir le document complet
12
CDC20B is required for deuterosome-mediated centriole production in multiciliated cells
... ice for 5 min in lysis buffer ...instructions. For each immunoprecipitation, ...°C for 10 min with Bolt ™ LDS Sample Buffer and Bolt reducing agent, then separated on 4–12% gradient Bolt precast gels ... Voir le document complet
16
Auxin Perception Is Required for Arbuscule Development in Arbuscular Mycorrhizal Symbiosis
... reported for Medicago truncatula, maize (Zea mays), and soybean (Glycine max; Ludwig-Müller et ...which is deficient in auto- regulation of nodulation, suggesting that IAA might play a role in the ... Voir le document complet
13
Dystrophin Dp71 is required for neurite outgrowth in PC12 cells.
... Dp71 is essential for neurite outgrowth in PC12 cells and to our knowledge constitute the first direct evidence indicating a role for Dp71 in neuronal function and ...explanation for this ... Voir le document complet
18
Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
... autophagy is required for glucose ...role for autophagy in the management of systemic energy ...MAP kinase signaling, and cell proliferation and ...there is likely to be a ... Voir le document complet
25
Rab7A is required for efficient production of infectious HIV-1.
... components required for HIV-1 formation, we explored the role of eight ubiquitously expressed Rab proteins (Rab1A, Rab4A, Rab5A, Rab6A, Rab7A, Rab8A, Rab9A, Rab11A) involved in the endocytic and exocytic ... Voir le document complet
21
VAPYRIN-like is required for development of the moss Physcomitrella patens
... MATERIALS AND METHODS Phylogenetic analysis VAPYRIN homologs were searched against a custom genome database of 77 plant species from the SymDB database (Radhakrishnan et al., 2020) covering the main orders of plant ... Voir le document complet
12
CDC20B is required for deuterosome-mediated centriole production in 1 multiciliated cells
... fate marker a -Tub but poorly grow cilia. (d) Bar graph showing quantification of α-Tub/GFP double positive cells per field of observation. (e) Bar graph showing quantification of α- Tub/Ac-Tub/GFP triple positive cells ... Voir le document complet
73
Foxr1 is a novel maternal-effect gene in fish that is required for early embryonic success
... function is still largely ...it is a maternally-inherited transcript ( Schuff et ...foxr1 is mostly involved in male reproduction and ...foxr2 is thus far observed only on the X chromosome ... Voir le document complet
21
Spatiotemporal regulation of the Greatwall : PP2A axis is required for mitotic progression
... >@,QWHUHVWLQJO\,IRXQGWKDWF\FOLQ%HQWHUV WKHQXFOHXVEHIRUHWKDW*ZOGHORFDOL]HVLQWRF\WRSODVP>@,QGHHGXSRQ PLWRWLFHQWU\LQLWLDO ORZ F\FOLQ %&GN DFWLYLW\ LV VXIILFLHQW WR WULJJHU LWV RZQ QXFOHDU L[r] ... Voir le document complet
158
Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
... used for analyses of asymmetric division ...used for the quantitation of asymmetry in cell division, there was still a significant difference in the localization of the two labels ...enriched for old ... Voir le document complet
15
Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer
... confirmed that Bmi1 mutation caused a significant, dose-dependent reduction in the size of small adenomas (Figure 1c). Indeed, the median and maximal cross-sectional areas (CSA) of Bmi1 −/− adenomas were more than ... Voir le document complet
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