[PDF] Top 20 Genetic analysis of cell size homeostasis in human cells
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Genetic analysis of cell size homeostasis in human cells
... by cell number, type and size. Composed of around 30 trillion cells, humans have cells with remarkably varied functions and size, ranging from a neuron that can reach one meter ... Voir le document complet
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Control of gene expression by cell size
... participate in downstream gene repression in the tetraploid and the cln3 ∆ ...inhibitors of transcription in their kinase-inactive state and as activators of downstream transcription ... Voir le document complet
127
Comparative analysis of nanosystems' effects on human endothelial and monocytic cell functions.
... Viability of endothelial cells upon treatment with ...SEM of n=3 experiments and hexaplicate ...Real-time cell analysis. Cell index is displayed as x-fold of untreated ... Voir le document complet
45
Systems Level Analysis of Immune Cell Subsets and Intercellular Communication Networks in Human Breast Cancer
... tween cells in the TME? ...decomposed in multiple layers of information: tissue specificity, cellular infiltration, cell plasticity, soluble factors present in the environment, ... Voir le document complet
283
Impact of uranium uptake on isotopic fractionation and endogenous element homeostasis in human neuron-like cells
... case of U isotopic analysis in samples containing less than 300 ng of U ...(i.e., cell samples exposed to 1 µM of natural U) and Cu isotopic analysis in samples ... Voir le document complet
11
Constriction Rate Modulation Can Drive Cell Size Control and Homeostasis in C. crescentus
... compensation in the MreBQ26P mutant, in which cells elongate ...that cells will be longer when they achieve a critical concentration to initiate constriction, without disrupting ...role ... Voir le document complet
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In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes
... maintenance of liver homeostasis, we compared the abundance of apoptotic factors in the three cell systems (Figure 4 ...HepaRG cells and PHH were quite close, while HepG2 ... Voir le document complet
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Control of Transcription by Cell Size
... Our analysis of the transcriptional data suggests that the cell size signal may be transmitted by the mating and the filamentation MAPK ...pathways in S1278b were preferentially ... Voir le document complet
17
The influence of cell size on cytokinesis in situ and genomic interrogation of human cell size regulation
... genes in control cell ...number of reads in each sample. Antibody staining and FACS analysis The antibody against IgM (APC clone G20-127) was obtained from BD ...NALM-6 cells per ... Voir le document complet
173
Role of endocrine status and cell type in adhesion of human endometrial cells to the peritoneum in nude mice
... injection of endometrial cells did not show any ...role in the growth and spreading of ...regulate cell proliferation through autocrine or paracrine interactions (25, ...for ... Voir le document complet
8
Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis
... methods Cells Human samples were obtained following written informed consent under Boston University Institutional Review Board-approved protocols (H27007; H32371) in accordance with the Dec- ... Voir le document complet
20
Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells
... blot analysis At the end of the treatments, cells were harvested, washed twice with ice-cold PBS and lysed in a RIPA buffer (150 mM NaCl, 50 mM Tris-HCl pH ...µg of proteins were then ... Voir le document complet
45
Single-cell gene profiling of human regulatory T cell subsets in human graft-versus-host disease
... profiling of human regulatory T cell subsets in human graft-versus-host disease Shen Dong 1* , Sylvie Maiella 1 , Aliénor Xhaard 2 , Yuanyu Pang 1 , Christophe Becavin 3 , Arndt Benecke ... Voir le document complet
2
Genetic determinants of clinical heterogeneity in sickle cell disease
... In order to identify patients with the mildest disease we counted the number of clinical events experienced between birth and 18 ...number of years each participant attended the clinic to derive the ... Voir le document complet
238
Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells
... Hundreds of chromatin regulators (CRs) control chro- matin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain ...readout of 487 ... Voir le document complet
13
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis
... explored in a variety of clinical contexts including obesity, type 2 diabetes, Gaucher’s disease and cancer ...(55). In the case of glioblastoma, for example, increasing ceramide levels has ... Voir le document complet
31
Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro
... degrees of efficiency 100,145-150 ...introduction of exogenous DNA into the cells, often via viral vectors, which is an issue for potential biomedical ...identity of the generated myogenic ... Voir le document complet
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Cell-cell and cell-medium interactions in the growth of mouse embryonic stem cells
... number of cells in a cluster We next decided to investigate a more comprehensive measure of ...measure of self‐renewal. Since the process of self‐renewal consists of ... Voir le document complet
130
Analysis of the within-population genetic diversity and the effective size based on different kinds of information in selected animal populations
... frequency of some of them may increase in the dam gene pool but strong bottlenecks from one generation to another one act like a ...matter of fact, unbalanced use of sires is the cause ... Voir le document complet
150
Comparative Analysis of TGF-β/Smad Signaling Dependent Cytostasis in Human Hepatocellular Carcinoma Cell Lines
... stages of liver damage and regeneration, but exerts tumor promoting effects in onset and progression of liver ...background of such a switch, we systematically correlated loss of ... Voir le document complet
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