Top PDF Argonaute-2 is associated to brown adipose tissue activation
Argonaute-2 is associated to brown adipose tissue activation
... 1 . 3 month-old rats were daily intraperitoneally injected with CL 316,243 (1 mg/kg) or a saline solution (NaCl 0.9% w/v) (n=4). (A) Body weight, (B) glycemia and (C) iBAT weight expressed as a percentage of BW. ...
35
Human lipodystrophies: genetic and acquired diseases of adipose tissue.
... of adipose tissue are present with a high prevalence in the global population; in particular those linked with fat expansion leading to obesity, metabolic syndrome or type 2 ...localization. ...
30
Regionalization of browning revealed by whole subcutaneous adipose tissue imaging
... driving brown and white adipocyte differ- entiation or adipocyte hyperplasia and hypertrophy have now been well investigated and described ...that adipose depots differ from each other in terms of ...
10
Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice
... visceral adipose tissue (eWATectomy) A total of 10 male WT C57/BL6J mice (WT-eWAT) and 10 male Nrf2 − /− C57/BL6J mice (Nrf2-eWAT), 10 weeks of age and weighing approximately 25–30 g, were used for ...
12
Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2.: Prolactin and brown adipocytes
... and associated STAT5 activity are detected in most tissues at various stages of development [2,3]; in the fetus, on the other hand, PRLR emerge during mid-late gestation [4–6], when high expression levels are ...
40
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-κB
... expanding adipose tissue during obesity and its role in insulin resistance has been described and involves ...was to explore the expression of chemokines in inflamed adipose tissue in ...
10
Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance
... Cells To investigate the results of the reduced Rab4b expression in T cells on glucose and lipid homeostasis and insulin resistance, we generated mice in which the Rab4b gene was disrupted by homologous ...
20
Visceral Fat Accumulation During Lipid Overfeeding Is Related to Subcutaneous Adipose Tissue Characteristics in Healthy Men
... sc adipose tissue depots were measured by magnetic resonance ...led to a ...these 2 depots, but the increase in visceral depot was positively associated with the mag- nitude of the ...
9
Anti-Obesity Effect of Carotenoids: Direct Impact on Adipose Tissue and Adipose Tissue-Driven Indirect Effects
... belonging to the stromal vascular fraction of adipose tissue, especially macrophages, are able to produce and secrete ...inflammation associated with abnormal secretion of cytokines [ 6 ...
15
Reduced adiponectin expression after high-fat diet is associated with selective up-regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue
... Experiment with low-, normal-, or high-fat dietary supplementation After the acclimatization period, animals received a vitamin A–deficient [0 retinol equivalent (RE)/kg diet] diet for 10 wk that contained 5% sunflower ...
11
Adipose tissue expression of gelatinases in mouse models of obesity.
... of adipose, vascular and nervous tissues (20). Formation of adipose tissue, the major cellular component of fat pads is a complex process requiring commitment of mesodermal stem cells ...
6
Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
... Chromatin immunoprecipitation assay ChiP was performed as previously described [ 8 ]. Briefly, 100 mg of frozen VAT was fixed in 0.5% formaldehyde for 5 minutes and the reaction was stopped by adding a final ...
14
Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment
... factors associated with incident prediabetes or diabetes were, as expected, older age, family history of diabetes, Black or Hispanic origin, overweight/obesity, central obesity, dyslipidemia, metabolic syndrome, ...
35
Complement activation links inflammation to dental tissue regeneration
... hypothesized to complement the activity of the innate immune system ...Complement activation is initiated by fixation of antibodies to pathogen surface antigens [14, ...Complement is ...
24
Impact of inflammation on the metabolic changes associated with obesity : dialogues between adipose tissue and the intestine
... three adipose depots. This increased local chemotaxis was associated with a rapid and massive WAT macrophage accumulation, combined with fat mass reduction, changes in body composition and reduced ...
251
Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue
... led to a robust differentiation of 78% of mutant mASC-Egr1 −/− cells into beige adipocytes ...mASC is a less efficient process compared to white differentiation ...contrast to white adipocyte ...
16
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
... loss is associated with a decrease of 10 in serum CXCL5 concentration (median: 2230 versus 2040 pg/ml, p % = 0,006), suggesting that CXCL5 circulating concentration is controlled by WAT ( ...CXCR2. ...
12
Persistent low body weight in humans is associated with higher mitochondrial activity in white adipose tissue
... FIGURE 2 Transcriptomic analyses of adipose tissue at ...correspond to the log 2 fold change (FC) and false discovery rate (FDR) of ...test to assess the statistical significance ...
12
A decrease in brown adipose tissue activity is associated with weight gain during chemotherapy in early breast cancer patients
... BAT is known to affect energy metabolism in murine ...leads to obesity [ 13 ...led to obesity in mice [ 14 ...F-FDG is currently used in oncology to mark tumours but it is ...
8
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
... ER is a critical organelle for coordinating cellular homeostasis during states of high metabolism, but the specific pathways and ER-resident proteins that contribute to the adaptation of BAT to a ...
34