[PDF] Top 20 Analysis of shared heritability in common disorders of the brain

... evaluating the differences in real data, simulation work (table S5), and quantifying the magnitude of effect for potentially implied misclassification (table ...S6). In comparison with ... Voir le document complet

... Discussion In this study, we identified human genes and pathways involved in CM, suggesting possible targets for drug ...development. The key findings of this study are (1) the efficacy ... Voir le document complet

... mutations in the endosomal sodium/hydrogen exchanger 6 protein (NHE6) ( Pescosolido et ...variety of endosomal phenotypes in iPSC-derived neurons as well as cellular phenotypes related to ... Voir le document complet

... that the glioma subtypes have different molecular profiles pos- sibly resulting from different etiologic pathways, which might be shared by tumor subtypes or be type ...explore the possibility that ... Voir le document complet

... present in both blood and brain [13, 14]. Because the blood signature is derived from non-neuronal tissue and the brain signature is masked by non-HD related processes such as hypoxia, ... Voir le document complet

... deep brain stimulation (DBS); 3 patients had DBS over the FU and were censored at the time of ...use in the previous 12 months and baseline ...survival analysis to ... Voir le document complet

... differences in T2D as compared with the UKBS controls (or against just the 58C ...controls). The plots show histograms of normalised intensity ratios for 6 ...Examination of ... Voir le document complet

... SAUVAGNAT, François, op.cité. Marcel Czermac dit aussi sur l’action de neuroleptiques : « Enfin s’agissant des neuroleptiques, voici comment je qualifie leur action : pour autant que les manifestations psychotiques ... Voir le document complet

... on the CRS-R did not demonstrate functional use of objects in case 1 but it was noted that this patient tended to grab his bed sheets and try to reach ...within the motor cerebral areas ... Voir le document complet

... functional brain damage and their behavioral/cognitive profile, consistent with previous studies establishing neural correlates of behavior, language and ...highlight the importance to develop new ... Voir le document complet

... assessment of the level of consciousness can be complicated with secondary medical problems, which dimin- ish the chance to detect signs of consciousness at the patient’s ...very ... Voir le document complet

... All of these studies are using a mitigated loop, which only has one circuit connected to the geothermal ...to the previous work of the authors involved herein, two novel applications ... Voir le document complet

... The injectrode is a multifunctional probe designed to treat neurological disorders through targeted chemical and electrical stimulation directly to a focal point withi[r] ... Voir le document complet

... performed in 31 patients with ...neurological disorders, brain injury less than a month before scanning were ...used the auditory startle reflex test to exclude patients who could not shut ... Voir le document complet

... that the group of traumatic patients with DOC had more injury in the thalamus/midbrain, pons, hypothalamus, basal forebrain and cerebellum, as compared to the group of ... Voir le document complet

... on the positive affect (hedonia) and on the sense of purposefulness or engagement in life (eudemonia) [ 48 ...Despite the general view that quality of well- being is diminished ... Voir le document complet

... examine the residual brain function in some DOC patients (see Chatelle et al 2012 , Liberati and Birbau- mer 2012 , Noirhomme et al 2013 for ...changes in fMRI or EEG signals and to provide ... Voir le document complet

... disturbances in eating behaviour has been often associated to socio-cultural factors that influence the psychopathology of these ...disorders. The alarming increase in the ... Voir le document complet

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet

... Shared use allows for a more efficient utilization of existing railway infrastructure but requires a strong coordination between the infrastructure manager (IM) and [r] ... Voir le document complet