Pulmonary arterial hypertension (PAH)
BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart
... We read with great interest the article by Van der Feen and colleagues (1), who reported the promising results from a multicenter preclinical validation of BET (bromodomain and extraterminal motif) family inhibition for ...
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Compromised cerebrovascular regulation and cerebral oxygenation in pulmonary arterial hypertension
... diastolic arterial pressure; ERA, endothelin receptor antagonist; F, female; HR, heart rate; iPAH, idiopathic PAH; M, male; MAP, mean arterial pressure; mPAP, mean pulmonary arterial pressure; ...
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Beyond a single pathway: combination therapy in pulmonary arterial hypertension
... Correspondence: Olivier Sitbon, Service de Pneumologie et Soins Intensifs, CHU de Bicêtre, 78 rue du Général Leclerc, F-94275, Le Kremlin-Bicêtre, France. E-mail: [email protected] ABSTRACT There is a strong ...
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Clinical Pharmacology of Endothelin Receptor Antagonists Used in the Treatment of Pulmonary Arterial Hypertension
... Pulmonary arterial hypertension (PAH) is a rare condition characterized by severe remodeling of the small pulmonary arteries leading to chronic pre-capillary pulmonary ...
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Rehabilitation in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: results from the Grenoble experience
... with pulmonary arterial hypertension (PAH) due to the fear of a possible risk of sudden cardiac death, arising from worsening hemodynamics and deterioration in right heart function during ...ESC/ERS ...
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Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension
... PH: pulmonary hypertension; PAH: pulmonary arterial hypertension; CTEPH: chronic thromboembolic PH; iPAH: idiopathic PAH; CTD-PAH: connective tissues diseases associated PAH; CHD-PAH: ...
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Patient-Specific Computational Analysis of Ventricular Mechanics in Pulmonary Arterial Hypertension
... May 10, 2016 Abstract Patient-specific biventricular computational models associated with a normal sub- ject and a patient diagnosed with pulmonary arterial hypertension (PAH) were devel- oped to ...
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Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension.
... Idiopathic pulmonary arterial hypertension (IPAH) corresponds to precapillary pulmonary hypertension in which there is neither a family history of the disease, nor an identified risk ...
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Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension
... FIGURE 3 Scatterplot of variant (red cell distribution width (RDW)) associations (x-axis) plotted against variant ( pulmonary arterial hypertension (PAH)) associations (y-axis) where each dot ...
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en fr New insights in the pathogenesis of pulmonary arterial hypertension Nouveau regard sur la physiopathologie de l’hypertension artérielle pulmonaire
... : Hypertension pulmonaire, remodelage vasculaire pulmonaire, cellule musculaire lisse, cible ...Summary Pulmonary arterial hypertension (PAH) is a severe and incurable cardiopulmonary ...of ...
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Olfactory receptors in pulmonary arterial hypertension: A novel pathway of vascular remodeling?
... Abstract Pulmonary arterial hypertension (PAH) is due to progressive obstruction of pulmonary arteries, thus leading to right heart failure and ...
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en fr Role of p53 protein in human and experimental pulmonary arterial hypertension Rôle de la protéine p53 dans l’hypertension artérielle pulmonaire humaine et expérimentale
... Introduction Pulmonary arterial hypertension (PAH) is a rare and severe disease in which pressure elevation in the pulmonary arteries (PA) leads to right heart failure and ...of ...
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Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry.
... mean pulmonary artery pressure; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; PAH, pulmonary arterial hypertension; PAWP, pulmonary artery wedge pressure; PH, ...
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Prediction of new onset of resting pulmonary arterial hypertension in systemic sclerosis.
... exercise-induced pulmonary hypertension; FUPH: onset of pulmonary arterial hypertension during follow-up; PH: pulmonary hypertension; TRV: tricuspid regurgitation ...
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Vasoreactive Pulmonary Arterial Hypertension Manifesting With Misleading Epileptic Seizure: Diagnostic and Treatment Pitfalls.
... pulmonary hypertension. An adapted invasive assessment of pulmonary pressure and pharmacological challenge allowed for diagnosing vasoreactive pulmonary arterial ...of pulmonary ...
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View of Heart failure in idiopathic pulmonary arterial hypertension: the pitfalls to be avoided
... Keywords Pulmonary arterial hypertension · Right heart failure Introduction L ’hypertension artérielle pulmonaire (HTAP) postembo- lique, les HTAP liées à l ’hypoxémie chronique et aux attein- ...
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Hypoxemia during sleep and overnight rostral fluid shift in pulmonary arterial hypertension: a pilot study
... in pulmonary arterial hyper- tension, but the underlying mechanisms remain ...in pulmonary arterial ...disease pulmonary arterial hypertension underwent a polysomnography ...
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Determinants of exercise-induced pulmonary arterial hypertension in systemic sclerosis.
... Exercise-induced pulmonary arterial hypertension (EIPH) in systemic sclerosis (SSc) has already been observed but its determinants remain ...nary arterial pressure (sPAP) was derived from the ...
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Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.: RAAS-activity in iPAH-patients
... Idiopathic pulmonary arterial hypertension (iPAH) is a fatal disease with an average mortality rate of 58% within 3 years after ...excessive pulmonary vascular remodeling, leading to elevated ...
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en fr Role of progenitor cells in human and experimental pulmonary arterial hypertension Rôle des progéniteurs dans l’hypertension artérielle pulmonaire humaine et expérimentale
... fibrocytes is due to their increased pulmonary vascular recruitment. This hypothesis, raised by Frid et al [5] is not consistent with data obtained in PAH lungs by us and others [2], describing normal fibrocyte ...
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