"Endothelin-converting enzyme-like 1 (ECEL1)"
Étude de l'Endothelin-converting enzyme-like 1 (ECEL1), un nouveau membre de la famille de l'endopeptidase neutre-24.11 (EPN)
... Mais cette observation est surtout évidente dans des expériences de biotinylation de surface de cellules HEK-293 transfectées, où deux formes de ECELI, soit 105 et 100 kDa respectivement[r] ...
265
Modulation of Endothelin-1 and Insulin-like Growth Factor Type 1-induced Signaling by Curcumin in A-10 Vascular Smooth Muscle Cells
... produced by the heart, kidney, lung, posterior pituitary and central nervous system (10, 16, 17). In the cardiovascular system, ET-2 and ET-3 are expressed at very low levels. 1.4 Biosynthesis of ET-1 Several ...
133
Role of the human chymase (CMA1) in the conversion of big-endothelin-1 to endothelin-1 (1-31)
... angiotensin converting enzyme/chymase paradigm in the production of angiotensin-II from angiotensin-I [32], the ECE plays an important role in the production of the circulating levels of ET-1 whereas ...
109
Peroxisome Proliferator-Activated Receptor gamma enhances the activity of a insulin degrading enzyme-like metalloprotease for amyloid-beta clearance.
... (Table 1), compatible with (a) metallo- protease(s) in the Aβ-degradation ...Table 1): i) 1,10-phenanthroline blocks IDE, NEP, MMPs, ACE, and ECE [34,52]; ii) phospho- ramidonblocks NEP, ECE, and ACE ...
20
Les récepteurs de nectines/ nectines-like DNAM-1 et CRTAM [Nectins and nectin-like receptors DNAM-1 and CRTAM: new ways for tumor escape]
... Dessarthe 1 , Aurélie Thedrez 1 , Olivier Toutirais 3 > Les nectines et nectines-like (Necl) sont des molécules d’adhérence exprimées dans de nombreux types de ...
8
The enzyme-like catalytic activity of cerium oxide nanoparticles and its dependency on Ce 3+ surface area concentration
... substrates 29 and produce the superoxide species O ! !• . Subsequently, Seal and coworkers proposed that nanoceria dismutate O ! !• and disproportionate H 2 O 2 in a similar way as the enzymes superoxide dismutase (SOD) ...
18
Mécanisme de contrôle de l'entrée en mitose par Polo-like kinase 1 (PlK1)
... résidus) très divergente, et d’un domaine catalytique C-terminal (350 résidus) bien conservé entre les espèces 184 . Des analyses réalisées chez le Xénope ont révélé qu'une région de la partie N-terminale était ...
131
Mathematical Programming of Peirce-Smith Converting
... smelting- converting-SC-grinding-FF-leaching-SX-EW [9, 15, ...smelting- converting-casting-EW, or smelting-converting-SC-grinding-FF-casting-EW [9, ...
295
A Cheeger-like inequality for coexact 1-forms
... h 1 to λ 1 1 , we shall first relate h 1 to the L 2 -Rayleigh quotient of α (as in Cheeger’s ...the 1-form β such as its integral over γ(x, T ) is the length of γ(x, T ...L 1 ...
34
Lipopolysaccharides et glucagon-like peptide 1 : des mécanismes moléculaires à la physiopathologie
... 34 système immunitaire intestinal en l’entraînant quotidiennement pour faire de lui une véritable arme de guerre… Bref, la conversation entre nos bactéries et nos cellules est perpétuelle afin de faire en sorte que ...
351
Targeting the vascular tone of microarterioles with an endothelin-1 (ET-1) antagonist selectively modulates tumor blood flow and promotes response to treatment
... an endothelin-1 (ET-1) antagonist selectively modulates tumor blood flow and promotes response to ...Martinive 1 , Pierre Sonveaux 1 , Chantal Dessy 1 , Vincent Grégoire 2 , ...
1
Enzyme de restrictions
... Un plasmide résistant à la kanamycine et à l’ampicilline est coupé avec l’enzyme Pst I, enzyme coupant dans le gène de résistance à l’ampicilline. L’ADN est ligaturé avec les produits de digestion de l’ADN de ...
1
Endothelin-1 and H2O2-induced signaling in vascular smooth muscle cells : modulation by CaMKII and Nitric oxide
... then hydrolyzes the membrane phospholipid, phosphatidylinositol-4’,5’-bisphosphate [PtdIns(4,5)P 2 ] to generate two second messengers: hydrophobic diacylglycerol (DAG), which remains in the membrane, and soluble ...
269
Molecular Basis of Complement C1q Collagen-Like Region Interaction with the Immunoglobulin-Like Receptor LAIR-1
... Abstract: The immune system homeostasis relies on a tight equilibrium of interconnected stimulatory and inhibitory signals. Disruption of this balance is characteristic of autoimmune diseases such as systemic lupus ...
18
Iontophoresis of endothelin receptor antagonists in rats and men.
... The relationship between the pharmacodynamic effect of ERAs on microvascular function and their efficacy in the prevention of digital ulcers in patients at risk remains uncertain. Two groups have studied the effect of ...
10
Converting sugarcane waste into charcoal for Haiti
... The work of the Edgerton Development Lab, under the guidance of Amy Smith, has developed a process utilizing an oil drum kiln to convert readily available agricultural waste from s[r] ...
47
Peroxidase-like behavior of Ni thin films deposited by glancing angle deposition for Enzyme-free uric acid sensing
... Tripathi 1 , Kenneth D. Harris 2,3 , Anastasia L. Elias 1 1 Department of Chemical and Materials Engineering, University of Alberta, Donadeo Innovation Centre for Engineering, Edmonton, Alberta, T6G ...
3
Targeting the ROS-HIF-1-endothelin axis as a therapeutic approach for the treatment of obstructive sleep apnea-related cardiovascular complications
... 3.3. Role in vascular dysfunction and remodeling In rats exposed to intermittent hypoxia, allopurinol treatment (through its xanthine oxidase-‐ inhibiting property) attenuated the impairment in acetylcholine-‐mediated ...
43
Converting EKG signals into 3-D stereo sound
... What needs to be done most likely to improve this technique is to work on externalizing the sound, moving it through vertical space (using head motion for exampl[r] ...
86
Regulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) : relevance to diabetic vasculopathy
... Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a newly identified vascular receptor for oxidized LDL (0xLDL) and advanced glycation end products (AGEs). LOX-1 is high[r] ...
404