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[PDF] Top 20 Optimization of adenoviral vectors for cancer suicide gene therapy

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Optimization of adenoviral vectors for cancer suicide gene therapy

Optimization of adenoviral vectors for cancer suicide gene therapy

... adenovims mutant that replicates selectively in p53-deficient human tumor celis. ONYX-015: clinical data are encouraging. The role ofthe E1B 55 kDa gene product in oncolytic adenoviral v[r] ... Voir le document complet

129

Cytosine Deaminase Suicide Gene Therapy for Peritoneal Carcinomatosis

Cytosine Deaminase Suicide Gene Therapy for Peritoneal Carcinomatosis

... vivo gene transduction, as only a small proportion of tumor cells can be reached following in vivo treatment with viral or liposomal ...CD gene therapy might be efficient on a number of ... Voir le document complet

7

Combined Suicide and Cytokine Gene Therapy for Peritoneal Carcinomatosis

Combined Suicide and Cytokine Gene Therapy for Peritoneal Carcinomatosis

... models of established tumours. We chose to use retroviral vectors as such vectors were previously demonstrated to be eYcient in our ...Moreover, adenoviral vectors can lead to important ... Voir le document complet

7

Synthesis of lutetium-carrying oligonucleotides for targeted cancer therapy and imaging

Synthesis of lutetium-carrying oligonucleotides for targeted cancer therapy and imaging

... Labelling of the aptamer with natural lutetium after coupling to a bifunctional chelator (1,4,7,10 tetra-aza- cyclo-dodecane-1,4,7,10-tetraacetic acid N- hydroxysuccinimide ester or DOTA-NHS ester), was evaluated ... Voir le document complet

1

Synthesis of water-soluble polymer-modified fullerenes for cancer photodynamic therapy

Synthesis of water-soluble polymer-modified fullerenes for cancer photodynamic therapy

... Photodynamic therapy (PDT) is a cancer treatment involving the irradiation of a photosensitizer that generates singlet oxygen ( 1 O 2 ), a cytotoxic species initiating tumor ...yield of ... Voir le document complet

1

Development of aptamer-based radiopharmaceuticals for targeted cancer imaging and therapy

Development of aptamer-based radiopharmaceuticals for targeted cancer imaging and therapy

... Bunka of the University of Leeds for their collaboration Discussion This SELEX experiment, for the selection of HER2 targeting aptamers, resulted in 26 selected RNA aptamers for ... Voir le document complet

1

Photodynamic therapy of cancer: an update.

Photodynamic therapy of cancer: an update.

... properties of PS agents have been summarized ...function of PDT, whereas others suggest that PSs that produce more apoptosis and less inflammation are suitable for applications such as brain tumors, ... Voir le document complet

32

Comparison between two treatment planning systems for volumetric modulated arc therapy optimization for prostate cancer.: VMAT with Monaco versus Pinnacle

Comparison between two treatment planning systems for volumetric modulated arc therapy optimization for prostate cancer.: VMAT with Monaco versus Pinnacle

... prostate cancer, VMAT solutions proposed by both TPS offered good PTV coverage and OARs sparing, with similar delivery ...except for the rectal ...volume of healthy tissue to reach the ...root ... Voir le document complet

28

Towards Computational Design of 3D Scaffolds for Cell-Based Gene Therapy

Towards Computational Design of 3D Scaffolds for Cell-Based Gene Therapy

... PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. ... Voir le document complet

3

Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration

Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration

... mutation of the Rho gene [ 30 ...development of pEYS611 gene therapy to slow down photoreceptor degeneration and to preserve visual performances in all RP patients regardless of ... Voir le document complet

23

View of Gene Therapy: A Promising Therapeutic Strategy for Malaria

View of Gene Therapy: A Promising Therapeutic Strategy for Malaria

... Manipulation of Mosquito Vector Competence Plasmodium transmission is dependent upon the Anopheles ...expression of effector genes within the Anopheles mosquito midgut, in order to express products that ... Voir le document complet

5

Vectors and Gene Delivery to the Retina

Vectors and Gene Delivery to the Retina

... consists of millions of neurons, including dozens of neuronal ...Retinal gene therapy aims to target these neurons in an efficient, safe, and specific way so that ther- apeutic ... Voir le document complet

21

Let there be light: gene and cell therapy for blindness.

Let there be light: gene and cell therapy for blindness.

... S. Gene therapy for Leber Hereditary Optic ...Preparation for the upcoming pivotal Phase III of the drug development will be ...examples of ongoing and completed gene ... Voir le document complet

32

Large Scale Production, Purification, and Modification of Chitosan-Based Complexes for Gene Therapy

Large Scale Production, Purification, and Modification of Chitosan-Based Complexes for Gene Therapy

... (consisting of 1-palmitoyl, 2-oleoyl phosphatidylcholine (POPC), cholesterol and the triglyceride triolein) by high speed mixing of lipids dissolved in ethanol, injecting into the first inlet, with an ... Voir le document complet

147

Anti-HER2 vaccines: new prospects for breast cancer therapy.

Anti-HER2 vaccines: new prospects for breast cancer therapy.

... HER-2/neu for the treatment of breast cancer or for the prevention of recurrent ...alteration of the immunogenicity of naturally occurring peptides, the use of ... Voir le document complet

44

Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies

Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies

... fragment of DNA polymerase I (NEB) and ...polymerase, for 35 ...ng of PCR products with the LCII-SEQ and LTRIV-SEQ primers, for 12 cycles with Q5 polymerase, and were purified with nucleoMag ... Voir le document complet

44

Aggregation of Synthetic Gene Delivery Vectors Enhance the Cellular Association and Uptake for in vitro Transfection

Aggregation of Synthetic Gene Delivery Vectors Enhance the Cellular Association and Uptake for in vitro Transfection

... In this study, the correlation of physicochemical properties of polymer- based synthetic gene delivery vectors (polyplexes) with cellular association as the first barrier for in vitr[r] ... Voir le document complet

1

Multimodal Registration and Data Fusion for Cardiac Resynchronization Therapy Optimization

Multimodal Registration and Data Fusion for Cardiac Resynchronization Therapy Optimization

... Fusion for Cardiac Resynchronization Therapy Optimization Franc¸ois Tavard, Antoine Simon, Christophe Leclercq, Erwan Donal, Alfredo ...Resynchronization Therapy (CRT) has been shown to ... Voir le document complet

11

Development of a multi-gene PCR assay for the prediction of the response to hormone therapy in breast cancer

Development of a multi-gene PCR assay for the prediction of the response to hormone therapy in breast cancer

... regions of target genes, and the E or ligand-binding domain, which bind estrogens and estrogen analogues 31 ...segment of the response element 33 ...presence of ligand. AF-1, located near the ... Voir le document complet

145

Poly(vinyl alcohol)-C60 nanohybrids for cancer photodynamic therapy

Poly(vinyl alcohol)-C60 nanohybrids for cancer photodynamic therapy

... Poly(vinyl alcohol)-C60 Nanohybrids for Cancer Photodynamic Therapy Hurtgen, M., Liège/B, Debuigne, A., Liège/B, Mouithys-Mickalad, A., Liège/B, Jérôme, C., Liège/B, Detrembleur, C., Liège/B, ... Voir le document complet

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