[PDF] Top 20 Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
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Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet
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Proteinase-activated receptor-2-induced colonic inflammation in mice : Possible involvement of afferent neurons, nitric oxide, and paracellular permeability
... produced by cNOS and plays an anti-inflammatory role, maintaining mucosal integrity by tonic secretion of low quantities of NO ...(21). In con- trast, lack of cNOS activity or ... Voir le document complet
7
Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium
... profiling by mRNA- seq from whole small intestinal tissue, extracted colon crypts, and sorted stem, proliferative, and adult entero- cytes from the small intestine ...(Fig. 2 a–e, Additional file 1 : ... Voir le document complet
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The role of inflammation induced by radiation or lipopolysaccharides in the metastatic process in a mouse model of breast cancer
... mainly by toll-like receptor-4 (TLR-4) but also by CD 14 glycosylphosphatidylinositol-anchored molecule located on • activated macrophages (Fujihara et ...resulting in prostaglandin and ... Voir le document complet
108
Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model
... Figure 2. Effect of PAR1 antagonist on hMPV infection during a 5-day treatment in ...Groups of 18 mice were infected intranasally with hMPV (6-8 x10 5 TCID 50 ) or mock infected and ... Voir le document complet
14
AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells
... lysed in ice-cold lysis buffer containing 50 mM Tris-HCl, pH ...determination of total protein content with a BCA protein assay kit (ThermoFisher Scientific, Life Technologies SAS, Courtabœuf, ...separated ... Voir le document complet
17
Nod2 protects remote small intestinal sites in case of colonic inflammation.
... BMSC of the same genetic background (WT→WT or KO→KO) served as ...monitored in Peyer’s patches of chimeric mice via flow ...Percentages of CD45.1 and CD45.2 positive cells. (B and C) ... Voir le document complet
31
Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation
... α 2 δ ligands bind to the α 2 δ subunit exclusively expressed by high-voltage gated channels ( Cheng and Chiou, 2006 ...). Of the four isoforms, PGB seems to exhibit greater affinity for α ... Voir le document complet
11
Activation of PAR-2 increases colonic permeability by MLCK activation and INF-c-dependent
... Nicolas Cenac, Rafael Garcia Villar, Laurent Ferrier, Jean Fioramonti, Lionel Bueno. Activation of PAR-2 increases colonic permeability by MLCK activation and INF-c-dependent[r] ... Voir le document complet
4
Activation of a Dimeric Metabotropic Glutamate Receptor by Inter-Subunit Rearrangement
... terminus of the G protein α subunit, triggering its activation ...role of this remains elusive (6- ...their activation, ...reorientation of the two subunits, may contribute to stabilize ... Voir le document complet
26
Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation
... bladder inflammation and related pain ( Lantéri-Minet et ...as in our study, found increased sensitivity in the lower abdominal ...scores in CYP-treated animal, evidence that this ... Voir le document complet
10
Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models
... performed by using 5 ng/µL of DNA, 0.2 µM of primers, and 1X KAPA HiFi HotStart Ready Mix (Roche, Boulogne-Billancourt, France) in a final volume of 25 ...followed by 25 cycles ... Voir le document complet
13
Src is activated by the nuclear receptor peroxisome proliferator-activated receptor beta/delta in ultraviolet radiation-induced skin cancer
... 7G). In vivo UV exposure increases PPARb/d expression at the transcriptional level and its ...Once activated, PPARb/d upregulates Src expression and activity, which in turn, boosts EGFR/Erk1/2 ... Voir le document complet
21
Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway
... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet
27
Chronic Activation of Wild-Type Epidermal Growth Factor Receptor and Loss of Cdkn2a Cause Mouse Glioblastoma Formation
... basis of histopathological features, clinical presentation and molecular characteristics (reviewed in (1, ...features of GBM are uncontrolled cellular proliferation, extensively diffuse infiltration, ... Voir le document complet
19
Activation of the peroxisome proliferator-activated receptor alpha protects against myocardial ischaemic injury and improves endothelial vasodilatation.
... protein in the two vascular preparations. Relaxa- tion in response to the NO-donor, SNAP, was hence stud- ied in both the mesenteric bed and the aorta, in order to test the hypothesis ... Voir le document complet
11
Induction of Early Transcription in One-Cell Mouse Embryos by Microinjection of the Nonhistone Chromosomal Protein HMG-I
... groove of AT-rich DNA, an interaction mediated by a specific DNA-binding domain, the “AT-hook,” which is distinct from and unrelated to the “HMG box” present in other HMG proteins (Reeves and Nissen, ... Voir le document complet
19
Cloning and characterization of putative vomeronasal receptor genes in mouse
... However, as for the rat family, and indeed still for the main olfactory receptor genes first cloned by Buck and Axel (1991), the receptors will remain putative until their function[r] ... Voir le document complet
37
Dexamethasone prevents visceral hyperalgesia but not colonic permeability increase induced by luminal protease-activated receptor-2 agonist in rats
... Version postprint Comment citer ce document : Roka, R., Ait-Belgnaoui, A., Cartier, C., Garcia Villar, R., FIORAMONTI, J., Eutamene, H., Bueno, L. (2007). Dexamethasone prevents visceral hyperalgesia but not colonic ... Voir le document complet
9
CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation.
... knockdown of CIAP2 Antisense phosphorothioate oligodeoxyribonucleotides (AS ODNs) directed to c-iap2 messenger (m)RNA and negative control ODNs have been designed and manufactured by BIOGNOSTIK ...cells ... Voir le document complet
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