[PDF] Top 20 Increased Atherosclerosis in Mice Deficient in Perilipin1.
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Increased Atherosclerosis in Mice Deficient in Perilipin1.
... high in both Plin1 -/- Ldlr -/- and Ldlr -/- mice but did not differ between the two groups of mice (table ...mmHg in Ldlr -/- mice) and heart rate (547 ± 25 vs 515 ± 23 b/min) were ... Voir le document complet
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The use of an adapted model allows contributing to the “Reduction” of mice used in experimental protocols: the case of the apoE–deficient (apo E-/-) mice in a model of atherosclerosis control
... of mice used in experimental protocols: the case of the apoE– deficient (apo E -/- ) mice in a model of atherosclerosis ... Voir le document complet
2
Inulin attenuates atherosclerosis in apolipoprotein E-deficient mice
... E-deficient mice: Atherosclerosis Atherosclerosis is an important risk factor of CVD (Charakida et ...mortality in Wes- tern countries (Steinberg et ...of atherosclerosis ... Voir le document complet
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The SH2 domain containing 5-phosphatase SHIP2 is expressed in the germinal layers of embryo and adult mouse brain : increased expression in N_CAM deficient mice.
... adulthood in restricted brain ...Using in situ hybridization technique with multiple synthetic oligonucleotides, we dem- onstrated that SHIP2 mRNA was highly expressed in the ventricular zone at ... Voir le document complet
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Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice
... automatically as part of the IVDr platform as previously described [ 27 ]. 2.8. Analysis of mRNA expression After an initial extraction step by mixing Extract-All (Eurobio, France) and chloroform to samples, total RNA ... Voir le document complet
12
PPARbeta in macrophages and atherosclerosis
... involved in lipid uptake and storage such as SRA, CD36 and ...incubated in vitro with OxLDL, treatment with the PPARligand GW0742 did not modify OxLDL uptake, while OxLDL degradation slightly ... Voir le document complet
21
Nutrigenomic analysis of the protective effects of bilberry anthocyanin-rich extract in apo E-deficient mice
... involved in lipid metabolism and inflam- mation at an early-onset stage of ...level in the plasma possibly via an increased elimination as bile ...level in the liver via a decreased hepatic ... Voir le document complet
12
Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.
... three mice with either high-grade dysplasia or carcinoma were ...penetrance in WKO mice at only 4 months of age, which is a higher penetrance than that observed for non-irradiated WKO mice ... Voir le document complet
25
Reduction of brain metastases in plasminogen activator inhibitor-1-deficient mice with transgenic ocular tumors
... demonstrated in wound healing (Lund et ...increase in the levels of proteases or their ...technology, increased FGF-1 production in primary tumors was detected at mRNA levels and confirmed at ... Voir le document complet
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Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor
... difference in the percentage of mature vessels between PAI-1 proficient and deficient mice (Figure 2F, ...switch” in tumors might represent a mirror image of an angiogenic switch induced by an ... Voir le document complet
33
Colonic Proteome Signature in Immunoproteasome-Deficient Stressed Mice and Its Relevance for Irritable Bowel Syndrome
... immunoproteasome in the regulation of intestinal permeability has been previously suggested both in mice during water avoidance stress (WAS) and in patients with irritable bowel syndrome ... Voir le document complet
50
Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
... used in conjunction with either AMPKα1 or AMPKα2 knockout ...female mice have rarely (if ever) been ...MacKO mice and WT littermates, there is a potential sex-specific trend whereby AMPK signaling ... Voir le document complet
31
GABA and Glutamate Pathways Are Spatially and Developmentally Affected in the Brain of Mecp2-Deficient Mice
... reduced in the hippocampus of symptomatic Mecp2-deficient ...affected in this homeostatic response, but also the machinery involved in the vesicular incorporation of GABA and the chloride ... Voir le document complet
16
Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae
... increase in the expression of CXCL9 48 h post-infection compared to WT ...an increased expression of IL-17A and CD40 in lung homogenates of WT in comparison with Ghrh −/− mice 48 h ... Voir le document complet
16
Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response
... Migration in HCAEC Our in vivo outcomes pointed to a possible role of CS interfering locally with the inflammatory response of endothelium in atheroma ...CS in inflamed human coronary aortic ... Voir le document complet
21
Dendritic cell differentiation and immune tolerance to insulin-related peptides in Igf2-deficient mice
... IGF-2 in immune development and ...expressed in the thymus epithelium of different species (9, ...dwarf mice, which develop a thymic hyperplasia (11) with an increased number of thymocytes ... Voir le document complet
7
Earlier onset of tumoral anglogenesis in matrix metalloproteinase-19-deficient mice
... Mmp-19 increased the onset of skin tumor ...Mmp-19+/+ mice. In order to compare evolution of tumor invasion and vascularization in these genotypes, transplants were resected after 14 and 21 ... Voir le document complet
32
Deficiency of Antigen Presenting Cell Invariant Chain Reduces Atherosclerosis in Mice
... of atherosclerosis, which B cell replacement can reverse in the case of ...and mice 9 – 11 or apolipoprotein E-deficient (Apoe −/− ) 12 mice with malondialdehyde-modified LDL (MDA-LDL) ... Voir le document complet
23
Mitochondrial biogenesis in fast skeletal muscle of CK deficient mice: Mitochondrial biogenesis in CK deficient mice
... expressed in skeletal muscle. In fast glycolytic skeletal muscle, deletion of the cytosolic M isoform of CK in mice (M-CK-/-) leads to a massive increase in the oxidative capacity and ... Voir le document complet
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Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
... participate in athero- genesis because they can promote the proliferative re- sponse of SMC through the release of PDGF after adher- ence and aggregation at focal sites endothelial denudation ...platelets ... Voir le document complet
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