[PDF] Top 20 Fatty acid metabolism and modulation of human breast cancer cell survival

... We focused specifically on the role of TG accumulation induced by treatment with oleate in the protection from apoptosis induced by serum and growth factor (GF) withdrawal in two ceil un[r] ... Voir le document complet

... lines and culture conditions M4Beu, a human melanoma cell line, was established in the laboratory of ...specimens and has been maintained in culture cell for almost 15 years ... Voir le document complet

... including cell adhesion, metabolism, and epithelial mesenchymal ...component of cadherin-based adherens junctions, and as a key nuclear effector of the Wnt ...classes of ... Voir le document complet

... RhoA and Rac1 could be a mediator of the SDF-1α ef- ...the cell-sorting gate set-up in ...co-culture of 2 or 5 days with BMHC. The sorted cells displayed an increase of Rac1 and ... Voir le document complet

... regulation of insulin ...inhibition of cdk5, or p35 deficiency resulted in increased insulin secretion in isolated ...effects of p35 deficiency were mediated by cdk5, since inhibition of cdk5 ... Voir le document complet

... Overrepresentation of macroH2A1.1 correlated with mesenchymal features and induction of EMT features in HMLE cells is accompanied by an increase in ...Analysis of GSE16795 data set ...each ... Voir le document complet

... (CPT2) and Very Long Chain AcylCoA Dehydrogenase (VLCAD) deficiencies belong to a group of more than fifteen genetic dis- eases affecting one of the enzymes of the mitochondrial ß-oxidation ... Voir le document complet

... increase breast cancer risk, through lipid ...potential modulation of the association between dietary iron intake and breast cancer risk by an antioxidant supplementation ... Voir le document complet

... program of gene regulation initiated by cofactor recruitment results in many enzymatic modifications that can basically be divided into two classes: ATP-dependent nucleosome remodeling and histone tail ... Voir le document complet

... ; metabolism ; Animals ; Blood Glucose ; metabolism ; Cell Cycle ; physiology ; Cyclin-Dependent Kinase 4 ; metabolism ; E2F1 Transcription Factor ; metabolism ; Energy ... Voir le document complet

... inhibited cell spreading and lamellipodia exten- sion (Figure 2A), leading to cell rounding associated with a disorganisation of the actin ...rounding of MDA-MB-231 is consistent with a ... Voir le document complet

... intake and consumption of fats and red meat, together with an increase in the amount of fibers and vitamin D in the diet, may be direct or indirect protective factors against ... Voir le document complet

... concentration and as such promote a glycolytic phenotype mediated, in part, through the HIF-signaling ...During cancer initiation, a hypoxic environment would favor the activation of genes associated ... Voir le document complet

... Comparison of lipid recovery by Soxhlet extraction utilizing hexane 3.2. Fatty acid profile The GC-FID techniques have been proven to be suitable for chemical profiling of food and ... Voir le document complet

... activity, and vimentin expression, the human vimentin promoter was found to be directly activated by β-catenin/ TCF-4 ...induction of the vimentin promoter by cotransfection of β-catenin ... Voir le document complet

... Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic ...Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures ... Voir le document complet

... Committees of the clinical centers taking part in the study and was approved by the National Institute of Cancer (INCa), following the recommendations of the French National Authority ... Voir le document complet

... Materials and Methods Patient Characteristics For this study, a well characterized collection of paraffin-embedded breast tumor tissue samples from 320 patients with BC was ...time of ... Voir le document complet

... deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private research ... Voir le document complet

... concentrations of glucose, in the presence or absence of malate (Table ...(malate and su­ gar) were totally removed. Production of biomass was slightly decreased in the presence of ... Voir le document complet