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[PDF] Top 20 Evaluation of nanoparticles and aptamers for in vivo tumor targeting using optical imaging

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Evaluation of nanoparticles and aptamers for in vivo tumor targeting using optical imaging

Evaluation of nanoparticles and aptamers for in vivo tumor targeting using optical imaging

... Au cours des dernières années, la nanomédecine a été très impliquée dans le développement de nanoparticules, terme qui concerne les matériaux et systèmes dont les structures ont une échelle de longueur comprise entre ... Voir le document complet

177

Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

... melanoma tumor uptake of 111 In-DOTA-F3B aptamer compared to the 111 In-DOTA-control-sequence was confirmed ex vivo by autoradiography and by scinti- graphic ...human ... Voir le document complet

17

New generation of magnetic and luminescent nanoparticles for in-vivo real-time imaging

New generation of magnetic and luminescent nanoparticles for in-vivo real-time imaging

... tendency of charged NPs to be destabilized under harsh pH and ionic strength environment, as encountered in biological ...media. In order to enhance the selective internalization of ... Voir le document complet

52

EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles

EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles

... injected in subcutaneous-capan-1-tumor bearing mice and the quantitative monitoring of the UNPs in different organs after iv injection was achieved by MRI ...accumulation of ... Voir le document complet

14

Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma

Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma

... pharmacokinetic and toxicity evaluation of gadolinium-containing nanoparticles and their antibody ...distribution of unconjugated (NP), anti-SLAMF7 antibody-conjugated ... Voir le document complet

13

Application of aptamers for in vivo Molecular Imaging and Theranostics

Application of aptamers for in vivo Molecular Imaging and Theranostics

... rhodamine in a silica shell matrix ...MRI and fluorescence imaging, was conjugated with an anti-nucleolin aptamer before being further radiolabeled with 67 Ga for detection by SPECT ... Voir le document complet

40

Liposomes for PET and MR imaging and for dual targeting (magnetic field/glucose moiety): synthesis, properties and in vivo studies

Liposomes for PET and MR imaging and for dual targeting (magnetic field/glucose moiety): synthesis, properties and in vivo studies

... Conclusion In conclusion, we succeed in the synthesis of a new generation of liposomal formulations in which a 68 Ga-based radiotracer is attached on the surface of ultra ... Voir le document complet

25

Ultrafast imaging of in vivo muscle contraction using ultrasound

Ultrafast imaging of in vivo muscle contraction using ultrasound

... 2006兲 In this letter, an innovative way of imaging transient and local shear vibrations of an in vivo contracting muscle is ...motion of the muscle tissue in ... Voir le document complet

5

Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers

Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers

... forms of yeast RNA polymerase are highly homologous, in particular the two largest subunits, which rep- resent two thirds of the mass of the enzymes, we analyzed the effect of the FC ... Voir le document complet

9

Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles

Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles

... you for forwarding the Letter to the Editor about our recent publication 1 in which we advocated the use of air pouch leukocytosis as a second line in vivo test for ... Voir le document complet

5

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

... IL-6, and IL-8) and growth factors (TGF-β, PDGF (platelet-derived growth factor), and FGF2) activating fibroblasts, which changes their morphology from an elongated and fusiform shape to a ... Voir le document complet

35

Mapping the myoglobin concentration, oxygenation, and optical pathlength in heart ex vivo using near-infrared imaging

Mapping the myoglobin concentration, oxygenation, and optical pathlength in heart ex vivo using near-infrared imaging

... spectroscopic imaging; First derivative; Optical pathlength; Pig heart Article Outline The mapping of subepicardial hemoglobin (Hb) 1 + myoglobin (Mb) oxygenation in pig hearts has been ... Voir le document complet

17

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

... CSF-1R targeting by the BLZ945 inhibitor could lead to the switch of the TAM phenotype toward an anti-tumor phenotype in a glioma preclinical model thanks to GM-CSF and IFN-γ produced ... Voir le document complet

35

In vivo pink-beam imaging and fast alignment procedure for rat brain tumor radiation therapy

In vivo pink-beam imaging and fast alignment procedure for rat brain tumor radiation therapy

... flux and/or adjust the energy ...horizontal and vertical sizes of the beam to be precisely defined to match the tumor ...control. In addition, a two-dimensional X-ray detector setup is ... Voir le document complet

7

Development and evaluation of an intraoperative beta imaging probe for radio-guided solid tumor surgery

Development and evaluation of an intraoperative beta imaging probe for radio-guided solid tumor surgery

... challenge in radiotherapy treatments, from the first attempt of treating cancer with x-ray radiation in 1896, is to deliver controlled dose distribution to the tumor mass while sparing the ... Voir le document complet

214

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles

... hyaluronan-LbL nanoparticles tar- get hypoxic tumor pH in ...Increase in hydrodynamic size and (b) concomitant shift in surface charge during LbL assembly onto mock fluorescent ... Voir le document complet

10

Acousto-optic imaging : challenges of in vivo imaging

Acousto-optic imaging : challenges of in vivo imaging

... Acousto-optic imaging Because the camera exposure time is very long compared to the period of the ultrasonic modula- tion, they suggested to use a synchronous light excitation instead of a ... Voir le document complet

294

Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations

Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations

... Principle of oxidative stress evaluation by ...monitoring of the EPR signal in vivo in a control ...spectroscopy in association with molecular probes has been successfully ... Voir le document complet

22

Direct Validation of Aptamers as Powerful Tools to Image Solid Tumor

Direct Validation of Aptamers as Powerful Tools to Image Solid Tumor

... most of them are surface antigens over- expressed in cancer ...targets for imaging because of their direct ...use of imaging probes directed against specific biomarkers ... Voir le document complet

10

Design Considerations for Tumor-Targeted Nanoparticles

Design Considerations for Tumor-Targeted Nanoparticles

... with using nanoparticles as in vivo diagnostics and therapeutics: 1) high background retention in the RES, 2) lack of complete elimination from the body, and 3) ... Voir le document complet

14

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