[PDF] Top 20 Computational approaches for the design and prediction of protein-protein interactions
Has 10000 "Computational approaches for the design and prediction of protein-protein interactions" found on our website. Below are the top 20 most common "Computational approaches for the design and prediction of protein-protein interactions".
Computational approaches for the design and prediction of protein-protein interactions
... The first component contains the single-residue or "self" contributions of amino acid aa to the energy difference between the unfolded and folded states. This [r] ... Voir le document complet
187
Development of chemogenomic approaches for prediction of protein - ligand interactions
... Description of the chemogenomic space possible only for proteins belonging to the same family, as already ...chemogenomic approaches in which the biological space is encoded on ... Voir le document complet
160
Designing helical peptide inhibitors of protein–protein interactions
... needed. For example, computational methods can be used to design custom libraries enriched in candidate high-affinity or high-specificity ...analyses and from prior experimental work, as we ... Voir le document complet
18
The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
... Analyzing the experimental structure and comparing it with its de novo design ( ...expected the first b-strand to be flanked by S2 and S8, but this is not the ...S5 and ... Voir le document complet
12
Computational Protein Design: trying an Answer Set Programming approach to solve the problem
... based approaches have been tried on the CPD problem ...element of the population is a sequence of amino-acids with their rotamer ...elements of the ...position. The ... Voir le document complet
19
A computational tool to predict the evolutionarily conserved protein-protein interaction hot-spot residues from the structure of the unbound protein
... with the exposed charged residues because both hydrophobic and electrostatic interactions are expected to contribute greatly to protein-protein binding ...identify the exposed ... Voir le document complet
34
Cost Function Networks to Solve Large Computational Protein Design Problems
... Protein engineering techniques coupled with high-throughput automated procedures make it possible to mimic the evolutionary process on a greatly accelerated time- scale, and thus increase the ... Voir le document complet
20
From Protein Corona to Colloidal Self-Assembly: The Importance of Protein Size in Protein-Nanoparticle Interactions
... (97) Welsch, N.; Becker, A. L.; Dzubiella, J.; Ballauff, M. Core–Shell Microgels as “Smart” Carriers for Enzymes. Soft Matter 2012 , 8 (5), 1428–1436. https://doi.org/10.1039/C1SM06894F. (98) Micsonai, A.; Wien, ... Voir le document complet
42
Assisted design of antibody and protein therapeutics (ADAPT)
... target. The ADAPT (Assisted Design of Antibody and Protein Therapeu- tics) platform aids in the selection of mutants that improve/modulate the affinity of ... Voir le document complet
18
Large-scale prediction of protein-protein interactions from structures
... Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the ... Voir le document complet
10
Protein contacts, inter-residue interactions and side-chain modelling.: protein contacts
... are the basic structural building units of ...are the cement of protein structures that control most of biological ...analyzed the sequence – structure relationship ... Voir le document complet
39
Molecular flexibility in computational protein design: an algorithmic perspective
... Heuristic and provable algorithms Because of its computational complexity, the rigid-backbone problem has been tackled using various heuristics, including greedy local search [45] and ... Voir le document complet
17
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila
... convenient for generating new fusions without additional fly transgenesis, swap- ping experiments require several generations, and therefore several weeks, before getting the desired BiFC-compatible ... Voir le document complet
25
Coev2Net: a computational framework for boosting confidence in high-throughput protein-protein interaction datasets
... To test the framework’s ability to predict interactions for which there is often no structural data available and to assign confidence values to interactions, we re-trained Coev2Net on a[r] ... Voir le document complet
15
Protein-protein interactions and gene expression regulation in HTLV-1 infected cells.
... (19-20), and c-Jun (21) interact with Tax and can redundantly serve to mediate Tax-activation of the ...preference for CREB has been shown (22). Both CREB and Tax associate with ... Voir le document complet
11
Structural basis for Fe–S cluster Assembly and tRNA thiolation mediated by IscS protein–protein interactions
... Within the cell, the relative affinities of partner proteins for the IscS dimer, their Fe-loading state (IscU, CyaY, and IscX), as well as their relative concentrations together ... Voir le document complet
19
Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability
... Protein-protein interactions within FAS-II of ...with the Y2H analysis were confirmed for each protein of ...All the interactions between the ... Voir le document complet
13
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
... Site-specific protein labeling with resorufin ligase in living mammalian ...ligase and LAP-BFP were labeled with 5 μM resorufin-AM 2 for 10 min, then washed for 45 min before live-cell ...LAP ... Voir le document complet
10
en fr Géométrie des interactions protéiques Géometry of Protein Interactions
... at the AA and ABA groups, which reflects how adding 3D information about the protein improved the ...adding the CIPS pair potential score to the experimental values ... Voir le document complet
138
Characterization of protein-protein interactions involved in auxin signaling pathway in tomato
... roots) and flowers, while the expression of Sl-TPL3 and Sl-TPL4 is prevailing in ...Moreover, the overall intensity of gene expression evaluated by quantitative PCR evidenced a ... Voir le document complet
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