[PDF] Top 20 B cells with regulatory properties in transplantation tolerance
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B cells with regulatory properties in transplantation tolerance
... the regulatory B cells is the secretion of IL-10, which is one of the most potent anti-inflammatory cytokine to control ...IL-10 in suppression by B cells has been demonstrated ... Voir le document complet
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Regulatory B Cells and Tolerance in Transplantation: From Animal Models to Human
... effector cells requires IL-21 and CD40-dependent cognate interactions with T cells ( 22 ...the regulatory function of B cells was antigen specific in an EAE and in ... Voir le document complet
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Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation
... Myeloid cells play a key role in this process: they initiate effective and controlled immune responses that protect the ...myeloid cells with regulatory properties can protect ... Voir le document complet
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Cell therapy using tolerogenic dendritic cells in transplantation
... dendritic cells Over the last few years, we have generated and charac- terized tolerogenic BMDC in rats, mice and non-human ...primates. In these different models, injection of tolero- genic BMDC ... Voir le document complet
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Regulatory role of natural killer T cells in diabetes
... iNKT cells are a relatively rare lymphocyte population in humans, as they represent less than ...iNKT cells with CD1d ea-GalCer tetramers and 6B11 antibodies have permitted a thorough study of ... Voir le document complet
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Regulatory T cells fulfil their promise ?
... patients with hematological malignan- ...resulting in haploidentical ...situation, in which the delicate balance between immu- nity and tolerance has yet to be ...T cells are included ... Voir le document complet
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Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
... immunological tolerance through CD4 + regulatory T cells could be a key element of future immunotherapies for several liver diseases allowing restoring the balance between proper immune responses and ... Voir le document complet
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Comparative Study of Immune Regulatory Properties of Stem Cells Derived from Different Tissues.
... participating in the study, in accordance with the Helsinki convention (1964) and French law relating to biomedical ...septum in dor- somedial area were washed with Dulbecco modified ... Voir le document complet
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Cell therapy using tolerogenic dendritic cells in transplantation.
... cells are harvested and characterized on their phenotype and their ...CD14-positive cells using ...of cells according to their size and density ...TolDC in AIMV medium (Gibco Life ... Voir le document complet
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Role of Regulatory T Cell and Effector T Cell Exhaustion in Liver-Mediated Transgene Tolerance in Muscle
... strategies. In other periph- eral tissues such as the skeletal muscle, anti-transgene immune response can result in partial or complete clearance of the transduced ...gene tolerance after ... Voir le document complet
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The use of mesenchymal stromal cells in solid organ transplantation
... Kidney transplantation, 826 56.1 Introduction Organ transplantation is the only definitive treatment for many critical diseases of the liver, kidney, heart, pancreas, and ...deal with the numerous ... Voir le document complet
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Alteration of CD8+ CD45RC[int/neg] regulatory T cells functions in Multiple Sclerosis and correlates with disease severity
... suppressive properties of rat and human CD8 + CD45RC int/neg Treg cells, expressing Foxp3 and acting through IFNg, TGFb and IL34 cytokines (Guillonneau, JCI, 2007; Bézie, JCI, 2015, Bézie, ...immune ... Voir le document complet
1
Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+regulatory T cells and are associated with poor prognosis in breast cancer patients
... were in close contact with tumor-associated Tregs (TATregs) within lymphoid aggregates in BTs and (2) the frequency of TApDCs strongly correlates with that of TATregs within BT, especially TN ... Voir le document complet
4
Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma
... Treg cells are crucial in mediating immune homeostasis and promoting the establishment and maintenance of peripheral ...These cells regulate a diverse array of immune responses in the context ... Voir le document complet
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Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells.
... fic regulatory T cells (Tregs) as a cellular therapy for autoimmune diseases is ...technology. In this study, we examined whether Tregs engineered through retroviral transduction to express a TCR ... Voir le document complet
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Identification of a common transcriptional signature for regulatory B cells in Humans and Mice
... Bregs with a proliferating state and provide new insights on possible mechanisms by which Bregs tightly regulate their ...homeostasis. In mice, Bregs exhibit a gene expression with function ... Voir le document complet
2
Fibrinogen-Like Protein 2/Fibroleukin Induces Long-Term Allograft Survival in a Rat Model through Regulatory B Cells
... tested in HEK293T cells transfected with lipofectamine reagent (Life Technologies, Carlsbad, ...later. Cells and supernatants were analyzed for FGL2 expression by FACS and western blot 48h ... Voir le document complet
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Microbial bioanodes with high salinity tolerance for microbial fuel cells and microbial electrolysis cells
... reported with felt graphite ...resulting in various promising microbial electrochemi- cal technologies such as microbial fuel cells (MFCs) or microbial electrolysis and electrosynthesis cells ... Voir le document complet
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Alloantigenic recognition properties of CD8+ regulatory T cells
... that in a rat major histocompatibility complex (MHC) mismatched heart allograft model, treat- ment with CD40Ig, a chimeric molecule that blocks CD40L, leads to indefinite allograft survival mediated by CD8 ... Voir le document complet
2
CD4(+)CD25(+) regulatory T lymphocytes in bone marrow transplantation.
... marrow transplantation is extensively used to correct hereditary defects (such as primary immunodeficiencies, metabolic diseases or hemoglobinopathies), hematologic malignancies (such as acute or chronic myeloid ... Voir le document complet
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