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sodium channels

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

... of sodium channels at the AIS, we evaluated the effect of concentrated in the AIS but not in the distal part of the axon ( ...and sodium channels (not ...

15

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.: Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.: Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin

... of sodium channels whose activation is negatively shifted by 200 nM Css IV, but not as much as the mutations of the gating charges R850Q and R853Q ...of sodium channels and in β-scorpion toxin ...

27

Voltage-Sensor Probes as efficient tools to screen for new modulators of voltage-gated sodium channels

Voltage-Sensor Probes as efficient tools to screen for new modulators of voltage-gated sodium channels

... Voltage-gated sodium channels (Nav) are molecular targets of clinically used drugs for treatments of various diseases (epilepsy, chronic pain, cardiac arrhythmia…) and also of numerous animal and plant ...

2

On the role of Nav1.7 sodium channels in chronic pain: an experimental and computational study

On the role of Nav1.7 sodium channels in chronic pain: an experimental and computational study

... Nav1.7 sodium channels in chronic pain: an experimental and computational study Alberto Capurro 1* , Jack Thornton 1 , Bruno Cessac 2 , Lyle Armstrong 1 , Evelyne Sernagor 1 ...

33

Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas

Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas

... of sodium channel expression in oysters. Phosphorylation of sodium channels by PKA and protein kinase C (PKC) has been shown to reduce the peak sodium current and modulates activation and ...

24

Voltage-gated sodium channels assemble and gate as dimers

Voltage-gated sodium channels assemble and gate as dimers

... oltage-gated sodium channels are expressed across exci- table cells where they are crucial for sharp initiation dynamics and propagation of the action potential 1 ...cardiac sodium channel α-subunit, ...

15

Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

... V channels combine both mechanical lever (obligatory) and ligand/receptor (allosteric) models: (i) Structural data of various Na V channel point to an elec- tromechanical (obligatory) coupling model in which the ...

19

Presynaptic hyperpolarization induces a fast analogue modulation of spike-evoked transmission mediated by axonal sodium channels

Presynaptic hyperpolarization induces a fast analogue modulation of spike-evoked transmission mediated by axonal sodium channels

... Nav channels from ...þ channels are inactivated in the axon of CA3 pyramidal cells, as in neocortical pyramidal neurons and hippocampal granule cells 18,19,33 ...

13

Skeletal muscle sodium channelopathies

Skeletal muscle sodium channelopathies

... voltage-gated channels that regulate rapid changes in ion fluxes, resulting in transient and drastic changes in cell membrane potential, the so-called action potential ...voltage-gated sodium ...

27

Influence de la microstructure de la thorine yttriée sur sa tenue au sodium, en vue de réaliser des sondes à oxygène dans les réacteurs au sodium de IVème Génération.

Influence de la microstructure de la thorine yttriée sur sa tenue au sodium, en vue de réaliser des sondes à oxygène dans les réacteurs au sodium de IVème Génération.

... au sodium tandis que les phénomènes de corrosion sont beaucoup plus marqués pour des composés à moyens et gros grains ...du sodium liquide pour des tests statiques à 320°C pendant 75 heures avec une ...

241

Études chimique et biologique de l’alginate de sodium oxydé par l’hypochlorite de sodium ou conjugué à la gélatine à travers la réaction de Maillard

Études chimique et biologique de l’alginate de sodium oxydé par l’hypochlorite de sodium ou conjugué à la gélatine à travers la réaction de Maillard

... Ce travail a pour but d'étudier la modification chimique de l’alginate de sodium par deux méthodes. La première est consacrée à la réaction d’oxydation de ce polysaccharide en présence de l’hypochlorite de ...

141

Bedload fill of abandoned channels

Bedload fill of abandoned channels

... flowing channels of the no-forcing experiments, as described in Section ...the channels, thus the water-surface slopes and their slope ratio between both distributaries could not be ...

295

Sodium Dihydrogen Phosphate Starting From Sodium Chloride and Orthophosphoric Acid Via Cation Resin Exchange

Sodium Dihydrogen Phosphate Starting From Sodium Chloride and Orthophosphoric Acid Via Cation Resin Exchange

... acidifying the quantity of resin present in the column. Then, the column was rinsed with 50 mL of water following the regeneration. For all the steps 1 to 3, the total quantity of liquid phase from the outlet of the ...

7

One-Step Synthesis of Sodium Trimetaphosphate (Na3P3O9) from Sodium Chloride and Orthophosphoric Acid

One-Step Synthesis of Sodium Trimetaphosphate (Na3P3O9) from Sodium Chloride and Orthophosphoric Acid

... SEM images of Syn-STM are shown in Figure 5. Solid product in homogeneous powder form was observed. EDX analysis was carried out on different points of sample and showed similar results. According to the results of ionic ...

5

Communication utilizing feedback channels.

Communication utilizing feedback channels.

... For example, a system operating over a white noise channel has an untimate error-free information rate attainable given by channel capacity; however, systems which signal at rates [r] ...

172

Routing into parallel collision channels

Routing into parallel collision channels

... Our contribution is in establishing sufficient conditions for the existence and uniqueness of a Nash equilibrium as well as for the DSC (and hence of the scalable equilibrium). First, we model the loss channels ...

4

Capacity Sensitivity in Continuous Channels

Capacity Sensitivity in Continuous Channels

... In order to obtain an estimate of the capacity sensitivity C p N 0 →p N,T , we seek to use Theo- rem 4. As conditions (C4)-(C6) are satised, all that remains is to show that condition (C7) also holds, which is veried ...

26

Continuous time channels with interference

Continuous time channels with interference

... time channels with adversarial delay errors in the presence of ...continuous-time channels in the presence of both delay errors and (signal) noise ...

8

Communication through channels in cascade

Communication through channels in cascade

... in the oaee of gaueslan additive noise and for sample by sample retransm1ssion at the intermediate station, it is shown that the optimum 1nput probability density 18 gaussian and that th[r] ...

134

Communication over fading dispersive channels.

Communication over fading dispersive channels.

... The basic problem to be considered is digital communication over a fading, dis- persive channel, accomplished by sending one of a set of M equiprobable signals a[r] ...

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