Neural stem cell
Neural stem cell pools in the vertebrate adult brain: Homeostasis from cell‐autonomous decisions or community rules?
... Adult stem cell populations must coordinate their own maintenance with the gener- ation of differentiated cell types to sustain organ physiology, in a spatially controlled manner and over long ...gle ...
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Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease.
... Endogenous neural progenitors have the ability to proliferate and/or migrate towards brain lesions in various pathological models as well as in the diseased human brain ( Arvidsson et ...Exogenous stem ...
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Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
... of cell fate preserving NSC arrangements in their physiological niche, (ii) it involves recording jointly the behavior of each individual NSC and its neighbors, and (iii) it faces the extremely slow dynamics of ...
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Vascular Endothelial Growth Factor Receptor 3 Controls Neural Stem Cell Activation in Mice and Humans
... the G1-S transition, such as cyclin D/E and cyclin-dependent ki- nases Cdk1/2, and of factors regulating chromosomal DNA repli- cation. Furthermore, VEGF-C stimulation appears to drive NSCs from their quiescent state ...
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Tissue-wide coordination of epithelium-to-neural stem cell transition in the Drosophila optic lobe requires Neuralized
... corrected. Cell distances to the TZ were calculated in Matlab by measuring the shortest distance of cell centroids to regions of interest drawn along apically constricted epi-NSCs expressing ...
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Fabrication and Surface Modification of Poly L-Lactic Acid Nanostructures for Growth Factor Immobilization and Neural Stem Cell Delivery
... from cell adhesion, be it in basal medium, EGF-free media or full media (11327 ± 1233, 9696 ± 1436 and 9187 ± 1037 cells, respectively, at day 2, see Figure ...promoting cell adhesion in a similar fashion ...
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Perlecan is required for FGF-2 signaling in the neural stem cell niche
... (1:400, Cell Signaling Tech, Boston, MA), rabbit polyclonal anti-EGF-Receptor (1:200, Chemicon, Temecula, CA), goat anti-doublecortin (DCX) (1:200, Santa Cruz Biotechnology, Santa Cruz, USA), mouse anti-NeuN ...
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Prion replication occurs in endogenous adult neural stem cells and alters their neuronal fate: involvement of endogenous neural stem cells in prion diseases.
... that neural precursor proliferation was enhanced in prion infected mice [16] the authors did not check the accumulation of PrP Sc in the cells of ...of neural stem cell in the progression of ...
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Mms19 promotes spindle microtubule assembly in Drosophila neural stem cells
... In Mms19 P mutant brains a higher proportion of NBs are in mitosis In order to better understand the microcephaly phenotype, we performed 5-Ethynyl-2’-deox- yuridine (EdU) incorporation assays coupled with phosphorylated ...
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Computational prediction of neural progenitor cell fates
... each cell by filling any holes inside the halos ...each cell groups the pixels into three ...the cell (green and yellow pixels in ...the cell pixels to separate touching ...
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Cell cycle features of primate embryonic stem cells.
... ES cell cycle, apart from it being unusually rapid, is a short G1 phase which represents approximately 15% of the total cell-cycle duration, or 2 ...the cell-cycle in asynchronously growing ...
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Cell-cell and cell-medium interactions in the growth of mouse embryonic stem cells
... on cell growth 6 ...depletion, cell‐cell communication/signaling is often an important modulator of cell ...of cell‐cell ...
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The cell-secreted microenvironment : shaping embryonic stem cell self-renewal and differentiation
... of cell-secreted signals are soluble signals that travel through the culture media to signal to other cells in the environment, but cells can also signal through direct contact with other cells or by extracellular ...
146
CHD7 promotes proliferation of neural stem cells mediated by MIF
... murine neural stem/progenitor cells (NSPCs); however, the downstream effectors of this factor remain ...During neural development, the chromatin remodeling factor Chd7 (chromatin helicase-DNA-binding ...
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Allogeneic hematopoietic stem cell transplantation for T-prolymphocytic leukemia: a report from the French society for stem cell transplantation (SFGM-TC)
... hematopoietic stem cell transplantation (HSCT) might possibly serve to consolidate the response to initial ...for stem cell transplantation ...
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Notch promotes neural lineage entry by pluripotent embryonic stem cells.
... ES cell differ- entiation is indicated by the kinetics and pattern of gene ...ES cell progression to differentiation ...ES cell state and have not advanced to a more mature egg cylinder stage ...of ...
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Cancer-Stimulated Mesenchymal Stem Cells Create a Carcinoma Stem Cell Niche via Prostaglandin E
... LoVo cell migration in LoVoMSC coculture treated with cytokine neutralizing antibodies as indicated. Data are means ± SE, n = 5. (E) MSCs increase invasion of LoVo tumors. LoVo (5 × 10 5 cells/injection) were ...
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The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
... embryonic stem cells, has been proposed to control pluripotency by maintaining TAp53 in an inactive form ( Ungewitter and Scrable, 2010 ...somatic cell reprogramming and increase the malignant potential of ...
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Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy
... (HLA)-match, stem cell source, intensity of conditioning (intensive versus reduced intensity, classified according to pub- lished working definition) (Bacigalupo et ...
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Unrelated donor haemopoietic stem-cell transplantation: ATG or not?
... blood stem- cells from unrelated donors after myeloablative conditioning, it is unclear whether some subgroups of patients do not benefit or even could be harmed by ATLG ...or stem-cell source could ...
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