Dendritic cells (DC)
Can dendritic cells see light?
... of dendritic cells, photo-induced signaling could be interfering with signaling from the TLR, and this interference could determine the relative gene expression levels of different DC markers such as MHCII ...
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Virosome-mediated delivery of tumor antigen to plasmacytoid dendritic cells.
... plasmacytoid dendritic cells to the virus is driven by the recognition of viral ssRNA by TLR7 and PKR ...GEN2.2 cells by CIRIV, on the contrary of Bungener’s work (25), who observed an increase of ...
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Cell therapy using tolerogenic dendritic cells in transplantation.
... tolerogenic dendritic cells Whereas clinical trials using immunogenic DC to treat cancer have been developed over the last 15 years [1,36], TolDC therapy is only just emerging in the clinical ...
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Beta 2-adrenergic stimulation of dendritic cells favors IL-10 secretion by CD4(+) T cells
... of dendritic cells lowers I-Ab expression in a Gi manner We hypothesized that salbutamol treatment disturbed the early DC signals needed for T lymphocyte ...+/+ cells were treated with ICI 118,551 or ...
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Purification and characterization of bovine dendritic cells from peripheral blood
... BOTH DC ENRICHED POPULATIONS HAVE THE CAPACITY TO SENSITIZE NAIVE T CELLS Dendritic cells are highly effective, as compared to other antigen-presenting-cells. at stimulating T-cells. ...
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Cell therapy using tolerogenic dendritic cells in transplantation
... tolerogenic dendritic cells Whereas clinical trials using immunogenic DC to treat cancer have been developed over the last 15 years [1,36], TolDC therapy is only just emerging in the clinical ...
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Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells
... Results Assessing the impact of genetic variation on pathogen-sensing in primary human DCs We developed an integrated experimental and computational pipeline (Fig. 1A) to identify variability in human DC responses and ...
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Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
... florent_ginhoux@immunol.a-star.edu.sg (F.G.) http://dx.doi.org/10.1016/j.immuni.2016.08.015 SUMMARY Dendritic cells (DCs) are professional antigen- presenting cells that hold great therapeutic poten- ...
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Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A
... Abstract Dendritic cells initiate adaptive immune responses, leading either to control cancer by effector T cells or to exacerbate cancer by regulatory T cells that inhibit IFN-c-mediated ...
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Role of myosin IIA in the small intestine immunosurveillance by dendritic cells
... by Dendritic Cells (DCs), sampling by macrophages that deliver antigens to DCs in the stroma, antigenic passage through goblet ...these cells have a different function from LP CD103 + CD11b + DCs, as ...
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Role of DC-SIGN in Lassa Virus Entry into Human Dendritic Cells
... Antigen-presenting cells, in particular dendritic cells (DCs), are early and preferred targets of LASV, and their productive infection contributes to the virus- induced immunosuppression observed in ...
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Altered innate functions of myeloid dendritic cells in ANCA-associated vasculitis
... Background Dendritic cells (DC) are critical effectors of innate and adaptive immunity, acting both as sentinels that detect the presence of pathogens and as key antigen-presenting cells that ...
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Étude génétique et fonctionnelle des Interferon-producing Killer Dendritic Cells
... mNK cells demonstrate a striking phenotypic resemblance to the interferon- producing killer dendritic cells (IKDC), which were initially described as a hybrid cell type exhibiting properties of both ...
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Dendritic Cells: More Than Just Adaptive Immunity Inducers?
... BETWEEN DENDRITIC CELLS AND NATURAL KILLER T LYMPHOCYTES Natural Killer T (NKT) cells bearing an invariant TCR (iNKT) need DC to become activated, as shown by the stimulation of human V 24 + CD8 + ...
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Dendritic cells mature to resist lamin degradation and herpes virus release
... mature dendritic cells, in this issue, Turan et ...ture dendritic cells and provide microscopic evidence that the nuclear capsid egress is blocked in mature dendritic ...immature ...
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Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells
... Conventional dendritic cells (cDCs) comprise distinct populations with specialized immune functions that are mediators of innate and adaptive immune ...
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A subset of dendritic cells as a major and constitutive source of IL-22BP
... of dendritic cells as a major and constitutive source of IL-22BP Jérôme Martin 1,2 , Gaelle Bériou 1 , Michèle Heslan 1 , Céline Bossard 3 , Anne-Chantal Knol 4 , Brigitte Dréno 4 , Simon Milling 5 , Miriam ...
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Activation of tolerogenic dendritic cells in the tumor draining lymph CD8+ T cells engineered to express CD40 ligand
... T cells are isolated from patients, expanded ex vivo and reinjected back into the patients to destroy tumor ...T cells can still be inactivated (tolerized) or deleted, limiting their therapeutic ...T ...
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Autologous Dendritic Cells Prolong Allograft Survival Through Tmem176b-Dependent Antigen Cross-Presentation
... using dendritic cells (DCs) is a promising approach to decrease doses of immunosuppressives in these settings ...tolerogenic dendritic cells (ATDCs) ...because cells can be prepared in ...
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Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
... ASC-GFP-derived dendritic cells incubated with HAdV-C5, IC-HAdV or ...ASC-GFP-derived dendritic cells 1 h ...ASC-GFP-derived dendritic cells after 1 h exposure to IC-HAdV after ...
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