cell leukemia
Human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein induces DNA damages through Activation-Induced cytidine Deaminase (AID)
... Cite this article as: Riquet et al.: Human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein induces DNA damages through Activation- Induced cytidine Deaminase (AID). Retrovirology 2014 11(Suppl 1):O45. ...
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Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells
... immunosuppressive responses, immune tolerance, 10 and poor survival of stage-III colorectal cancer patients, 11 suggesting a role of MGL in mediating cancer progression. Notwithstanding our current knowledge on the role ...
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Schnitzler syndrome associated with hairy cell leukemia presenting with chronic urticaria and arthralgias
... CASE REPORT In 2013, a 50-year-old man presented with com- plaints of arthralgia involving knees, ankles, and fingers, which primarily manifested during the night. A few months later, he developed recurrent episodes of a ...
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Rituximab therapy for hairy cell leukemia : a retrospective study of 41 cases
... Jérôme Tamburini & Coralie Barbe & Alain Delmer Received: 26 June 2014 / Accepted: 24 July 2014 / Published online: 7 September 2014 # Springer-Verlag Berlin Heidelberg 2014 Abstract The purine analogs (PAs) ...
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Melioidosis and hairy cell leukemia in 2 travelers returning from Thailand.
... Melioidosis occurs mainly in patients with underlying diseases such as diabetes (37%–60% of cases), chronic alcoholism (12%–39%), thalassemia, and chronic nephropathy, and in persons receiving long-term corticosteroid ...
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NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
... (CANNTG)–binding heterodimers with ubiquitous class I bHLH partners known as E-proteins, which include products of the E2A gene (E12 and E47), HEB, and E2-2 (Hsu et al., 1991, 1994a; Voronova and Lee, 1994). In ...
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Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia
... (T-cell leukemia/lymphoma1) family genes TCL1A, MTCP1 (mature T-cell proliferation), or TCL1B (alias TCL1/MTCP1-like 1 [TML1]), are relatively speci fic for T-PLL and are present in more than 90% of ...
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The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.
... M-MuLV-induced leukemia have provided insights into the multistep process of ...T cell leukemia virus (HTLV-1), the etiologic agent of adult T cell leukemia (ATL), can be transmitted by ...
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Impact of conditioning intensity in T-replete haplo-identical stem cell transplantation for acute leukemia: a report from the acute leukemia working party of the EBMT
... Discussion The development of T-replete haplo-SCT for the treat- ment of hematological malignancies has been consider- able over the last 5 to 10 years. Several RIC and MAC regimens have been designed by different groups ...
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Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia
... Table 1. Patients’ characteristics and outcome according to methylation status. Abbreviations: IM, immature; WBC (G/L), white blood cells; CNS, central nervous system; MRD (TP1), post-induction minimal residual disease; ...
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Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia
... and cell lines, total RNA was extracted with a RNeasy Mini Kit (Qiagen) as per manufacturer’s protocol and concentrations were measured on a Nanodrop 1000 spectrophotometer (Thermo ...
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A comparison between allogeneic stem cell transplantation from unmanipulated haploidentical and unrelated donors in acute leukemia
... The EBMT is a non-profit, scientific society representing more than 600 transplant centers mainly in Europe. The EBMT promotes all activity aiming to improve stem cell transplantation or cellular therapy, which ...
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Cell lines and animal model in the analysis of pharmacogenomics markers in childhood acute lymphoblastic leukemia
... B.3. MTX treatment: For the assessment of MTX sensitivity, after optimisation experiments (Figure 3), 7- to 10-week-old NSG mice were injected intravenously with 5x10 6 in vivo expanded pre-B patient’s leukemic blasts ...
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Morphology and expression status investigations of specific surface markers on B-cell chronic lymphocytic leukemia cells
... / La version de cette publication peut être l’une des suivantes : la version prépublication de l’auteur, la version acceptée du manuscrit ou la version de l’éditeur. For the publisher’[r] ...
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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
... T cell lines) were profiled using large-scale gene expression analysis on the GeneChip Human Genome U133 Plus ...The Cell cycle and Mitosis cluster identified from this analysis largely overlaps with the ...
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Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia
... ACKNOWLEDGMENTS We thank the members of the Look and Young laboratories for discussions and critical review and Jennifer O’Neil for initial experimentation and TAL1 plas- mids. We are grateful to Garrett Frampton and ...
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Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia
... NK cell precursor (NKP) gene ...NK cell phenotype, suggesting that these two populations can be differentiated on the basis of a specific transcriptomic pattern (Supplementary ...NK cell progenitors ...
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Promyelocytic leukemia zinc-finger induction signs mesenchymal stem cell commitment: identification of a key marker for stemness maintenance?
... (promyelocytic leukemia zinc-finger) also known as, ZBTB16, ZNF145 or Kruppel-like zinc-finger protein, belongs to the family of the transcriptional repressors POK (POZ and ...stem cell maintenance and ...
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The Sequence of Cyclophosphamide and Myeloablative Total Body Irradiation in Hematopoietic Cell Transplantation for Patients with Acute Leukemia
... poietic cell transplantations to a statistical center located at the Medical College of Wisconsin in Milwaukee and the National Marrow Donor Pro- gram Coordinating Center in ...
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HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way.
... Figure 1 Effects of celastrol on U937 culture proliferation and viability in vitro. Cells were seeded at 2 × 10 5 /ml in 96-well culture plate and treat- ed with indicated doses of celastrol for 1 d. A: Dose-dependent ...
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