Cancer progression
Adhesion-GPCRs in cancer progression and metastasis
... of cancer cell(s) from primary site to distant organs was a fascinating, albeit vexing, problem to study within cancer ...of cancer progression and metastasis primarily for two ...
161
Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion.
... and progression of breast cancer and this has led to its becoming a major target for breast cancer ...breast cancer cells has been extensively ...in cancer progression, such as ...
25
FGFR1 and WT1 are markers of human prostate cancer progression.
... The MelanA/MART1 gene encodes a tyrosinase that is a marker of melanocytic differentiation [26]. It can be rec- ognized by cytotoxic T cells [28] and has been considered as a target for immunotherapy [28]. A previous ...
12
Tumor cell and stromal cell interactions during breast cancer progression
... evidence that MT1-MMP is exclusively produced by myofibroblastic cells, and not by breast neoplastic cells. To gain new insight into the role of MT1-MMP during early steps of cancer progression MCF7 cells ...
8
Social environment mediates cancer progression in Drosophila
... interactions, cancer nega- tively affects host fitness, which should lead to the selection of host control mechanisms, including behavioral traits that best minimize the proliferation of malignant ...the ...
8
Role of the tumor microenvironment in regulating apoptosis and cancer progression
... in cancer. These cancer-associated fibroblasts (CAFs) contribute to the progression of many solid tumor types such as endometrial, breast, prostate and pancreatic cancers, and they are able to ...
25
Snail family regulation and epithelial mesenchymal transitions in breast cancer progression.
... in cancer progression depends on the tumor ...tumor progression are carcinosarcomas or metaplastic carcinomas, which represent fewer than 1% of invasive breast carcinomas, but carry a bad ...
45
en fr Impact of constitutively active androgen receptor variants on prostate cancer progression Impact des altérations du récepteur des androgènes sur les voies de signalisation liées à la différenciation cellulaire et à la progression du cancer de la prostate
... : Cancer de la prostate ; Variants constitutivement actifs du récepteur des androgènes ; Transition Epithélio-Mésenchymateuse (EMT) ; N-cadhérine ; Régulation transcriptionnelle Androgens play a key role in ...
182
Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression.
... the extracellular matrix (ECM) (14). Although there is mounting evidence that CAFs are good targets for new anti-cancer therapies ( 5 , 15 ) , recent studies reported tumor- inhibitory effects of CAFs on tumor ...
53
The damaging effect of passenger mutations on cancer progression
... slow cancer progression and lead to cancer meltdown ...of cancer development from the Deleterious Passenger Model 4,5 ...model, cancer cells can acquire both strong advantageous drivers ...
19
miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice.
... prostate cancer at progressively earlier stages and lower levels of prognostic risk ...prostate cancer have a long natural history, while others will progress to metastatic stage and die from their disease ...
9
Metformin and propranolol combination prevents cancer progression and metastasis in different breast cancer models
... of cancer is a dynamic process that also requires the gain of invasive and migratory ...breast cancer patients ...breast cancer cell abilities to migrate and invade in ...breast cancer is the ...
17
Colon-specific immune microenvironment regulates cancer progression versus rejection
... Discussion Most preclinical mouse models investigating the immune com- position of CRC tumors are based on the implantation of colon tumor cell lines under the skin. 36 , 37 Nevertheless, our past work has revealed that ...
15
en fr role of the SOCS-1 protein in the colorectal cancer progression Role de la protéine SOCS-1 dans la progression tumorale colique
... Socs1 is a member of a family of proteins which has been mainly described as negative regulators of JAK/STAT signaling (Valentino and Pierre, 2006). Socs1 is relatively specific to IFN-γ/STAT1 and IL-4/STAT6. Although ...
189
Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression
... and progression phases in many cancers, including prostate cancer ...prostate cancer and strongly associated with epigenetic silencing in ...prostate cancer cells suggest a silencing function ...
8
Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression.
... propranolol-treated cancer cells should be sensitized to metabolic stress inducing survival ...for cancer cells in blocking proliferation and inducing cell ...for cancer therapeutic applications ...
14
EMT and inflammation: inseparable actors of cancer progression.
... tumor progression. During tumorigenesis, cancer cells, innate immune cells (such as dendritic cells or tumor-associated macrophages, TAMs) and activated resident cells (such as cancer-associated ...
27
NOTCH pathway inactivation promotes bladder cancer progression
... bladder cancer (37, 38), there is substantial evidence indicating a tumor-suppressive ...bladder cancer found a significant association with a SNP in a region near to JAGGED1, and carriers of this SNP ...
8
Implication de MEK1 et MEK2 dans l'initiation et la progression du cancer colorectal
... colorectal cancer [510], although the downstream effector pathways involved remain ...tumor progression and metastasis to distant ...tumor progression, we have used an orthotopic implantation model ...
376
Un nouvel interrupteur oncogénique dans la progression du cancer de la prostate - L’« exceptionnel » ORAI3
... A new oncogenic switch in prostate cancer progression: the exceptional ORAI3 hétéromères ORAI1/3 au détriment des canaux homomériques ORAI1 formant les SOC. Ces résultats laissent penser qu’il est possible ...
4