adult neural stem cell
Period 2 regulates neural stem/progenitor cell proliferation in the adult hippocampus.
... neural stem/progenitor cell (NPC) division in the central nervous ...system. Adult hippocampal neurogenesis in mammals is a plastic process placed under the control of environmental stim- ...
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Characterization of unknown adult stem cell samples by large scale data integration and artificial neural networks.
... that stem cells differentiation and fate is triggered by a common genetic program that endows those cells with the ability to differentiate into specialized progen- itors and fully differentiated ...different ...
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Neural stem cell pools in the vertebrate adult brain: Homeostasis from cell‐autonomous decisions or community rules?
... Abstract Adult stem cell populations must coordinate their own maintenance with the gener- ation of differentiated cell types to sustain organ physiology, in a spatially controlled manner and ...
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Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
... of adult NSC populations is challenging: (i) it requires dynamic analyses of cell fate preserving NSC arrangements in their physiological niche, (ii) it involves recording jointly the behavior of each ...
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Perlecan is required for FGF-2 signaling in the neural stem cell niche
... An extracellular matrix niche for neurogenesis Previous studies have introduced the concept of the vascular niche for neurogenesis in the SVZ ( Shen et al., 2008; Tavazoie et al., 2008; Kojima et al., 2010 ). At the ...
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Adult Bone Marrow Neural Crest Stem Cells and Mesenchymal Stem Cells are not able to Replace Lost Neurons in Acute MPTP-lesioned Mice
... preclinical cell therapy experiments on PD animals models, neural differentiation-based therapy protocols were performed using stem cells from Wharton’s Jelly [46], dental pulp [47] and bone marrow ...
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Regenerative potential of primary adult human neural stem cells on micropatterned bio-implants boosts motor recovery
... primary adult hNSCs, compared with other treatments such as direct cell graft or scaffold-alone ...neuronal cell line hNT2 pre-seeded on the same scaffolds [29], and provides new insights into the ...
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Spinal Cord Injuries – How Could Adult Mesenchymal and Neural Crest Stem Cells Take Up the Challenge?
... spinal cord of rats, once they were treated with UCB-MSCs [86]. Another strategy consists into differentiating MSCs/NCSCs into myelinating cells just before transplanting them inside the lesioned spinal cord. For ...
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In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells.
... The cell lines described here are subject to patents, notably the D3 cell line is covered under patent WO200605679A1 and the STROC05 cell line is covered under patent ...
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Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.
... pluripotent stem cells (supplementary Figure ...MMC cell cycle blockade and apoptosis [19,20], in particular though SMAD signaling activation and blockade of MYC pathway ...‘‘stem cell’’ ...
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Minimally invasive Delivery of Microbeads with encapsulated, Viable and Quiescent neural Stem cells to the Adult Subventricular Zone
... additional cell types and facilitate additional cell-cell and cell-ECM ...encapsulated neural stem and endothelial cells to a stroke injury ...
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Vascular Endothelial Growth Factor Receptor 3 Controls Neural Stem Cell Activation in Mice and Humans
... SUMMARY Neural stem cells (NSCs) continuously produce new neurons within the adult mammalian ...into neural progenitor ...that adult hippo- campal NSCs express vascular endothelial ...
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Prion replication occurs in endogenous adult neural stem cells and alters their neuronal fate: involvement of endogenous neural stem cells in prion diseases.
... of stem cells, or the stimulation of endogenous neural stem cells (NSC) in the adult brain therefore constitute new interest- ing and promising ...a cell therapy approach, we rapidly ...
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Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease.
... both cell types, as well as the SVZ dissected out from normal adult brains and used as a positive control ( Jin et ...both cell types to recombinant rat SCF (100 ...both cell types, as ...
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Mechanisms underlying activation of neural stem cells in the adult central nervous system
... one, two, and four weeks post-irradiation. Irradiated rats had a worse performance than control littermates when they were tested two or four weeks following the training period in the Morris water maze (MWM) (Morris et ...
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Acquisition of cancer stem cell capacities after spontaneous cell fusion
... between stem cells (normal or tu- moral) and differentiated cells [ 13 , 29 – 32 ...that cell fusion can produce a hybrid with stemness capacity, even if neither parent possesses ...that cell fusion ...
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Impact of metabolic pathways and epigenetics on neural stem cells
... of neural stem cells (NSC) during embryonic stages and the first postnatal ...ized stem cells are capable of producing several different lineages, NSC produce different cell types sequentially ...
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Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian Regeneration
... Small numbers of cNeoblasts restore regenerative ability Irradiated planarians cannot regenerate (35) and suffer massive tissue loss because of failed replacement of aged differentiated cells (35, 36). However, ...
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Human mesenchymal stem cells reprogram adult cardiomyocytes toward a progenitor-like state through partial cell fusion and mitochondria transfer: Cell fusion-mediated cardiomyocyte reprogramming.
... of stem-cell mitochondria transfer in cardiomyocyte reprogramming, hMADS cells were pre-treated for a long time (>1 month) with low doses of ethidium ...other cell types [ 32 – 34 ] ...their ...
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Targeted Therapies in Adult B-Cell Malignancies
... agents, histone deacetylase inhibitors, and novel targeted drugs such as ibrutinib and idelalisib [ 76 ]. 3.3. Metabolic Process. In the early twentieth century, War- burg first discovered that cancer cells ...
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