Haut PDF The role of transcription factor Nrf2 in osteoarthritis
The role of transcription factor Nrf2 in osteoarthritis
... Background: Osteoarthritis (OA) is characterized by progressive cartilage destruction, synovial inflammation, and subchondral bone remodelling with increased inflammatory and catabolic ...levels of ...
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en fr Skin allergy to fragances : mechanism of action and role of the transcription factor Nrf2. From 2D to 3D models. Les allergies cutanées aux fragrances : mécanisme d'action et rôle du facteur de transcription Nrf2. Du modèle 2D au modèle 3D.
... Présentation du travail – Partie I 121 Les allergies et les irritations de la peau sont les problèmes les plus fréquents causés par les ingrédients parfumants. De nombreux terpènes odorants, présents dans les huiles ...
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Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
... a Role in Glucose Signaling in Pancreatic Beta ...expressed in human pancreatic islets and in the pancreatic beta cell lines HIT-T15, INS832 兾13, TC3, and Min6 ...expression ...
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en fr Role of the transcription factor Helios in hematopoietic stern cells Etude du rôle du facteur de transcription Helios dans les cellules souches hématopoïétiques
... l’irradiation, j’ai analysé la présence de foyers 123-4* #&6)* +()* 782* =:>E()F* 7()* :E)G+=&=)* montrent que les CSH He -/- :(=>(66(6=*;+G)*+$6'=(%;)*+(G:*H$I(:)*123-4*in vitro et in vivo. ...
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Transcription factor 21 expression in injured podocytes of glomerular diseases
... analysis of Tcf21‑expressing murine podocyte cell line. Based on the results of microarray and KEGG pathway analysis, including cytokine-cytokine receptor interaction, TGF-beta signaling pathway, ...
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Role of the repressor JDP2 in the amino acid-regulated transcription of CHOP
... binding of JDP2 to CHOP AARE and dimerization with ...with in vitro translated proteins and antibodies. The migration positions of the ATF2/ATF2 homodimer, ATF2/JDP2 heterodimer and ...
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Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development.
... MADS-domain transcription factors and other transcriptional ...present in large nuclear ...with the quantitative PCR fragments in the distal enhancer site (e) and weaker proximal ...
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Effect of seasonal acclimatization on the expression of the carp transcription factor Pit-1
... quantitative analyses ofthe hybridization signals revealed a significant higher Pit-l expression in ùe proximal pars distalis (PPD) and pars intermedia (PI) of the pitu[r] ...
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The role of the glucose-sensing transcription factor carbohydrate-responsive element-binding protein pathway in termite queen fertility (vol 6, 160080, 2016)
... results in the release of 20-hydroxyecdysone, which causes the production of cuticular hydrocarbon sex pheromone ...[66]. In the termite Zootermopsis (Archotermopsidae), ...
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The specific in vivo role of PPARgamma and its downstream signaling pathway in the pathophysiology of Osteoarthritis
... Generation of Inducible Cartilage-specific PPARγ-mTOR Double KO Mice Generation of inducible cartilage-specific PPARγ-mTOR double KO mice was performed by using the Cre-Lox ...µg/ml in PBS by ...
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Understanding the impact of the role factor in collaborative information retrieval
... analysis of task difficulty finally became negative again at the end of the ...that in the GS scenario, 55% (5/9) of the pairwise features exhibited significant ...
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Crystallographic studies of the metal-responsive transcription factor NikR
... Additional metal ions further increase the affinity for operator by binding to the site situated at the RHH-MBD domain interface, and perhaps by binding to one of several sit[r] ...
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Transcription factor dimerization activates the p300 acetyltransferase
... for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...not. The documents may come from teaching and research institutions in France or ...
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The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response
... BAP55— The above results raise the question of the mode of action of DMAP1, a poorly characterized protein containing a highly conserved SANT (SWI-SDA2-NcoR-TFIIIB) domain, ...
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Integration, Agglomeration and Specialization: The Role of Factor Mobility
... value of intensity in the immobile factor ...decrease of the range of stability for sector 1 but an increase for sector ...that the centripetal forces have gained ...
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Identification of the Imprinted KLF14 Transcription Factor Undergoing Human-Specific Accelerated Evolution
... disruption of genes under accelerated evolution or positive selection in the human lineage has been associated with ...mutations in FOXP2 underlie severe language and speech ...
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Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1
... for the Western ...induce the shEWS-Fli1 transcription and plated at clonal density for colony counts thanks to crystal violet staining performed after a 6-days incubation ...all the ...
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JASPAR 2020: update of the open-access database of transcription factor binding profiles.
... With the advent of high-throughput sequencing more than a decade ago, the number of PFMs derived from in vivo and in vitro experiments has increased dramatically, leading to ...
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en fr Role of the protein kinase CK2 in the activation of immune response induced by contact sensitizers - and its link with Nrf2 Rôle de la CK2 dans l’activation de la réponse immunitaire induite par les molécules allergisantes et son lien avec Nrf2
... colony-stimulating factor), CSF (colony stimulating factor), VEGF (Vascular Endothelial Growth Factor)], ainsi que les métabolites de l’acide arachidonique (Theoharides et ...
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Analysis of variation at transcription factor binding sites in Drosophila and humans
... that the loss of CTCF binding associated with a TFBS mutation is generally propor- tionate to its impact on motif PWM ...and in particular the most evolutionarily conserved ones, can be ...
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