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[PDF] Top 20 Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

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Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

... lence of NAFLD. It affects around 25% of the general population of western countries but over 60% in obese subjects and can reach 90% in Type 2 diabetic patients [ 2 ...effect of ... Voir le document complet

20

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

... paradox of hepatic insulin resistance, which is also associated with obesity and T2DM, is still not fully ...dimension of NAFLD ...expression of genes encoding enzymes involved in de novo ... Voir le document complet

54

Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease

Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease

... used in combination with modified diets to induce a robust steatosis to NASH ...testing of an anti-inflammatory approach to NASH treatment ...NASH in HFD-foz/foz mice (182). The diet-induced animal ... Voir le document complet

56

Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy

Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy

... incidence of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with ...specific of the ... Voir le document complet

18

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

... mapping of body weight and adiposity index identifies diet specific genetic control independent of ...calculated in (129S6xBALB/c) F2mice fed control diet (CHD) (black lines) or high fat diet (HFD) ... Voir le document complet

11

DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease

DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease

... deletion of SIRT1 disrupts DEPTOR signaling, promotes mTORC1 activation, and exacerbates the development of alcoholic fatty liver and liver injury in mice Our previous ... Voir le document complet

31

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome

... important roles in the etiology of obesity, type 2 diabetes mellitus and their complications through genotype x environment ...feeding in inbred mouse strains widely used in genetic and ... Voir le document complet

13

Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context

Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context

... fications of lipid metabolism could have an impact on the whole cell energy homeostasis, we next assessed glycogen meta- bolism in GSDIa liver and kidneys treated or not treated with fenofi- ... Voir le document complet

17

Pathogenic role of IL-15 in non-alcoholic fatty liver disease

Pathogenic role of IL-15 in non-alcoholic fatty liver disease

... organ in the body and plays important roles in protein, carbohydrate and lipid metabolic ...pathways. In proteins metabolism, liver participates in amino acids degradation to ... Voir le document complet

101

Specificities of Hepatocellular Carcinoma Developed on Non Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue 1H-NMR Spectroscopy

Specificities of Hepatocellular Carcinoma Developed on Non Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue 1H-NMR Spectroscopy

... Specificities of Hepatocellular Carcinoma Developed in Non Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue 1 H-NMR Spectroscopy 1 ... Voir le document complet

2

Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?

Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?

... role of insulin resistance and fatty acids such as stearic acid ...[50,66]. In keeping with the role of specific lipid derivatives and possibly free fatty acids, previous investigations ... Voir le document complet

32

Burn after feeding. An old uncoupler of oxidative phosphorylation is redesigned for the treatment of nonalcoholic fatty liver disease.

Burn after feeding. An old uncoupler of oxidative phosphorylation is redesigned for the treatment of nonalcoholic fatty liver disease.

... OXPHOS in mitochondria isolated from different human ...(ROS) in different tissues including the liver [28-30] ...level of some FAO enzymes such as acyl-CoA dehydrogenases and ETF-ubiquinone ... Voir le document complet

15

The veno-occlusive disease of the liver.

The veno-occlusive disease of the liver.

... a liver transplant for acute VOD have become long-term ...complication of high-dose regi- mens used as conditioning before BMT, for which a number of risk factors have been ...use of low-dose ... Voir le document complet

8

Elevated serum liver-type fatty acid binding protein levels in non-acetaminophen acute liver failure patients with organ dysfunction.

Elevated serum liver-type fatty acid binding protein levels in non-acetaminophen acute liver failure patients with organ dysfunction.

... marker of liver injury in patients with DILI in the absence of ALF ...ability of FABP1 in 198 acetaminophen (APAP)-ALF patients ...[8]. In contrast, FABP1 did not ... Voir le document complet

13

European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease?

European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease?

... for fatty liver ...continuum of actions tar- geting populations at different levels of ...lack of suffi- cient policies, with 19 countries (66%) scoring in the low and middle ... Voir le document complet

8

Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

... improve liver steatosis or at least prevent further worsening as compared to ...predictor of good response has been studied and should probably be the focus of future ...series of pathways ... Voir le document complet

38

Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes

Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes

... or non-normal respectively or as frequency for qualitative ...Comparisons of quantitative variables were analyzed by Student’s t test or Mann-Whitney tests when distribution was normal or non-normal ... Voir le document complet

17

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

... action of phosphate- activated glutaminase (PAG); replenishing the neurotransmitter ...accumulation in the synaptic cleft and over-excitation of the postsynaptic neuron ...mechanism of ... Voir le document complet

20

Tight junction proteins in gastrointestinal and liver disease

Tight junction proteins in gastrointestinal and liver disease

... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet

61

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

... normality of variables or residues and homoscedasticity were ...conditions of application were not fulfilled, non- parametric tests were ...presence of amyloid or Tau staining or GFP levels ... Voir le document complet

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