Top PDF The Role of Stroma in Breast Carcinoma Growth in Vivo
The Role of Stroma in Breast Carcinoma Growth in Vivo
... REACTION IN BREAST CARCINOMA Invasive or infiltrating ductal carcinomas, which represent the most common type of breast cancer, are characterized by a pronounced degree of ...
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Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
... centrifugation. The fibroblast fraction was cultured in Ham’s F10 medium containing L-glutamine (3 mM), insulin (5 mg/mL), T3 (1 nM), hydrocortisone (1 mg/mL), kanamycin ...serum. The epithelial ...
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The specific in vivo role of PPARgamma and its downstream signaling pathway in the pathophysiology of Osteoarthritis
... elevated in chondrocytes extracted from PPARγ- mTOR double KO mice compared to control mice (Figure 4 ...Our in vitro rescue studies using PPARγ expression vector and in vivo studies using ...
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EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma
... established in vitro cell migration/wounding assay to investigate the role of EHD2 in the aggres- siveness of Hs578T, MDA-MB-231 and MDA-MB-436 TNBC cells that are ...
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Combined treatment of human MCF-7 breast carcinoma with antibody, cationic lipid and hyaluronic acid using ex vivo assays
... Immunotargeting of the HER-2 receptor is essential for studying the viability of cancer cells in majority of human ...consist of administering monoclonal or modified ...
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Role of the microtubule-associated protein ATIP3 in cell migration and breast cancer metastasis
... into the bloodstream of nude mice to reca- pitulate the late, rate-limiting, steps of the metastatic process, and examine metastatic dissemination to various organs while avoiding any ...
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The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
... negative breast cancer types are generally more aggressive and prone to ...metastasize. The absence of Estrogen receptor-alpha (ERa) correlates with hormone-indepen- dent growth of ...
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The role of inflammation induced by radiation or lipopolysaccharides in the metastatic process in a mouse model of breast cancer
... mammary carcinoma cells were recovered from their secondary site and re-injected into mammary fat pads, tumors were formed (Naumov et a l, ...that the tumor-microenvironment interactions affected tumor ...
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The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.
... that the SHH signaling pathway is constitutively reactivated in tumors independently of the von Hippel-Lindau (VHL) tumor suppressor gene expression which is inactivated in the ...
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Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo
... CLR/RAMP3). In this study, real-time quantitative reverse transcription demonstrated a significant expression of AM mRNA in tumor samples from colorectal cancer (CRC) patients in clinical ...
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BMP7 Gene Transfer via Gold Nanoparticles into Stroma Inhibits Corneal Fibrosis In Vivo
... family of growth factors with more than 10 members [21,22]. The cornea has been reported to express several BMPs and their receptors ...apoptosis in the human cornea ...pivotal ...
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Tumor growth model for ductal carcinoma: from in situ phase to stroma invasion
... understood. The development of a precancerous lesion in epithelium, as hyper- plasia ...increases the risk of abnormalities. In particular, the disruption of ...
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en fr Role of stroma and Wound Healing in carcinoma response to ionizing radiation Rôle du stroma et la cicatrisation en réponse de carcinome à des rayonnements ionisants
... TBI, the TBI threshold limit being set at 10 Gy.s -1 and 50 Gy.s -1 being the most protective ...dose-rate. The physical basis behind the protective effect of FLASH in ...
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A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
... Isolation of bone marrow stroma cells— To obtain bone and bone marrow stromal cells for scRNA-seq, mice were sacrificed via CO 2 ...placed in Media 199 (ThermoFisher Scientific, Ref#12350039) ...
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Effects of a progestogen on normal human breast epithelial cell apoptosis in vitro and in vivo
... 33-38 The same biphasic effect of progestins on proliferation of normal mammary epithelial cells has been evoked as an explanation for the higher risk of breast cancer in ...
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Local Anesthetics Inhibit the Growth of Human Hepatocellular Carcinoma Cells
... However, the antiproliferative effect of LAs on HCC cells has to be balanced with the possible risks of LAs toxicity and wound healing ...difficulty in the clinical setting. ...
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Role of the Sec22b/E-Syt complex in neurite growth and ramification
... for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...not. The documents may come from teaching and research institutions in France or ...
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Alterations in Glycopeptides Associated with Herceptin Treatment of Human Breast Carcinoma MCF-7 and T-Lymphoblastoid Cells
... type of therapy has increased the cancer-free survival of patients, not all tumors respond to this treatment and cancers often develop resistance to the ...Despite the fact that ...
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Role of DNA methylation in INK4a-ARF-INK4b locus expression in breast cancer
... 75% of breast cancers are ER+. The CDK4/6 inhibitors, having the same role of endogenous p16/p15, associated with hormonotherapy appear as new standard treatment for metastatic ...
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Role de deux fractions du stroma thymique dans la leucemogenese des souris AKR
... (ALL), le lymphome lymphoblastique de l'enfant ("ChiTdhorrd lymphoblastic lymphoma" ou lymphome de Sternberg).. Il semblerait done qu'un bris de la differencia[r] ...
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