[PDF] Top 20 Role of bacteria in the etiopathogenesis of inflammatory bowel disease

... activate the expression of virulence genes [48] . The major virulence factors of CD-associated AIEC that have a role in their ability to survive and replicate within macrophages ... Voir le document complet

... results of this study show that 1 H MRS combined with SCS methodology can detect differences in the prevalence of inflammation in the colon of animals fed with both low ... Voir le document complet

... achieved in recent years, the pathogenesis of Inflammatory Bowel Disease (IBD) has not yet been fully ...commensal bacteria, in genetically susceptible subjects and ... Voir le document complet

... production of IL-6 is increased in RA [40] and its signalling plays a central role in joint inflammation and degeneration ...attenuation of collagen-induced arthritis in mice ... Voir le document complet

... important role in colitis, exacerbating the overall IBD pathogenesis ( 29 , 30 ...knock in mice to inducibly deplete pDCs following DT treatment, Arimura et ...). In these settings pDCs ... Voir le document complet

... tial role of ZAG in IBD. We first measured serum levels of ZAG using ELISA in IBD patients, UC (n = 70) and CD (n = 109), enrolled in the “Nancy IBD cohort” and healthy ... Voir le document complet

... from the colonic lumen of IBD patients contain higher amounts of IL-6, IL-8, IL-10 and TNF-α compared to exosomes from healthy subjects, and the levels of these pro-inflammatory ... Voir le document complet

... analysis of Bray–Curtis distance with each sample colored according to the studied group and stratified by age (< or > 3 ...represent the top three principal coordinates that captured most ... Voir le document complet

... pro- inflammatory response such as pyroptosis, which is a cell death response that involves the production of caspase-1, required for the secretion of mature IL-1β and IL-18 by ... Voir le document complet

... mediators of epithelial-stromal communication, are crucial in tissue ...homeostasis. Inflammatory Bowel Diseases (IBD) are multifactorial pathologies where the microenvironment and ... Voir le document complet

... 2 The aim of this article was to examine the potential contribution of the variations of ABCB1 gene to CS dependent ...models of inheritance and haplotype analysis using ... Voir le document complet

... Department of Pathology, APHP, and University Paris Diderot USPC, Paris, France ∗ ...one of the most signif- icant histological features used for the examination of colorectal biopsy ... Voir le document complet

... participates in epithelial repair [ 15 ...infection, the release and content of exosomes can be modified, thereby influencing inflammatory responses and immunity [ 17 ...]. In ... Voir le document complet

... Prevalence of AIEC was significantly higher in mucosa of CD subjects than healthy controls ...loss of Megamonas and Veillonella was observed in AIEC-positive ileal tissues, compared ... Voir le document complet

... Mutations in the type VII collagen gene COL7A1 are associated with IBD ( Freeman et ...Considering the major role of type VII collagen in keratinocyte polarity ( Dayal et ... Voir le document complet

... Importance of the role of CYLD in CD as revealed by CD-associated bacteria The genetic results point towards the implication of CYLD in IBD ...some ... Voir le document complet

... through the brain-gut axis likely has a key role in the pathogenesis of inflammatory bowel diseases ...(IBD). The brain-gut axis involves interactions between ... Voir le document complet

... array of treatment options, personal- isation of approach to IBD therapy is essential and remains a crit- ical unmet research ...withdrawn. The potential cost savings of any clinically useful ... Voir le document complet

... essential role in preserving the undifferenti- ated stem cell state and promoting proliferation (van de Wetering et al, ...2002). The canonical WNT pathway is activated by binding of a ... Voir le document complet

... for the migration of leukocytes from the circulation toward the colonic ...epithelium. In rats, inhibition of CD11b/CD18 (Mac-1) integrin leads to a reduction of damage ... Voir le document complet