[PDF] Top 20 Efficient gene delivery by sonoporation Is associated with microbubble entry into cells and the clathrin-dependent endocytosis pathway
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Efficient gene delivery by sonoporation Is associated with microbubble entry into cells and the clathrin-dependent endocytosis pathway
... HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...not. The documents may come from ... Voir le document complet
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Internalization of miPEP165a into Arabidopsis Roots Depends on both Passive Diffusion and Endocytosis-Associated Processes
... in the internalization of extracellular molecules and plasma membrane proteins into eukaryotic cells ...[8]. Clathrin-mediated endocytosis (CME) remains the most ... Voir le document complet
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Endocytosis of Chikungunya Virus into Mammalian Cells: Role of Clathrin and Early Endosomal Compartments
... If the replication cycle of alphaviruses has been largely studied [2] and differences have been reported regarding the mechanisms used to enter their target cell [32,33,34], CHIKV host-cell ... Voir le document complet
12
Ultrasound and microbubble-assisted gene delivery: insights for intracellular mechanism
... HeLa cells expressing Rab7-eGFP , the late endosomes marker ...delivered into lysosomes for degradation. Upon sonoporation, pDNA was localised mainly at the plasma membrane and ... Voir le document complet
20
Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes.
... Riezman The vacuolating cytotoxin VacA is a major virulence factor of Helicobacter pylori, a bacterium responsible for gastrodu- odenal ulcers and ...associates with lipid rafts, is ... Voir le document complet
16
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.
... survival and growth ...for the characterization of minute chromosome rearrangements using multiple color fluorescence in situ hybridization with chromosome-specific DNA libraries and YAC ... Voir le document complet
43
Infantile-Onset Ascending Hereditary Spastic Paralysis Is Associated with Mutations in the Alsin Gene
... 3,4 and Odile Boespflug-Tanguy 1 1 INSERM UMR384 et Fe´de´ration de Ge´ne´tique Humaine Auvergne, Faculte´ de me´decine, Clermont-Ferrand, France; 2 Service de Ge´ne´tique, Universite´ de Lyon, Lyon; and 3 ... Voir le document complet
10
Delivery of biomolecules into mammalian cells using anthrax toxin
... Translocation efficiency of cargos at the C-terminus of LFN (or LFN-DTA) has been analyzed using three common laboratory assays: planar lipid bilayer,37 protein synt[r] ... Voir le document complet
267
Vectors and Gene Delivery to the Retina
... Retinal gene therapy aims to target these neurons in an efficient, safe, and specific way so that ther- apeutic gene expression can bring on ...understand the principles organizing ... Voir le document complet
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Systemic gene delivery to the central nervous system using Adeno-associated virus
... Keywords: gene therapy, AAV, neurological disorders, neurodegenerative diseases, systemic delivery INTRODUCTION In the last decade, adeno-associated-virus (AAV)-mediated gene ... Voir le document complet
9
"Upping the ante": How to design efficient auctions with entry?
... auctions with a strategic seller deciding whether to incur a cost to hire secretly a shill bidder being able to bid in the same way as any real bidder in the ...auction. With exogenous ... Voir le document complet
48
Gene delivery to pancreatic exocrine cells in vivo and in vitro
... Mokola is a rabies-related virus and belongs to the family of Rhabdoviridae, as ves- icular stomatitis virus ...for the transduction of a variety of cell types, especially brain cells ... Voir le document complet
13
Chemical modification of the adeno-associated virus capsid to improve gene delivery
... without the reactive isothiocyanate functionality, was used as a control to prove the covalent linkage of FITC and to exclude the physical adsorption of the molecule on the AAV2 ... Voir le document complet
10
Fetal growth is associated with the CpG methylation of the P2 promoter of the IGF1 gene
... IUGR and the methylation of CpGs at the IGF1, IGF2, and INS loci in placenta or cord blood samples [ 24 ...within the regulatory region of IGF1 and INS genes, because these two ... Voir le document complet
8
Stem cells as gene delivery system to create cardiac biological pacemaker
... of the experimenters were that absence of oscillations is not due to sufficiently large number of gap junction ...vitro[5], cells had about 12 hours to develop gap junctions connections, the ... Voir le document complet
136
The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion
... Mefs is related to impaired recruitment of Prmt5 to the Dlk-1 ...monitored by RT-qPCR after treatment of the cells with LiCl (10 mM) for 24 ...WT and KO Mefs was monitored ... Voir le document complet
6
The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition
... Despite the apparently powerful activity of PAX-FOXO1s, data from animal models have led to t proteins do not efficiently trigger FP-RMS formation and spreading ...stem cells to produce significant ... Voir le document complet
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Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet
15
Chloroquine-enhanced gene delivery mediated by carbon nanotubes
... dual gene and drug delivery, after loading the DWCNTs with the drug chloroquine, a lysosomo- tropic compound that is able to promote escape from the lysosomal ...of ... Voir le document complet
12
The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage
... form by Fig. 3 Knockdown of HP1 γ in germ cells results in mitotic ...GC1 and GC2 cell lines. High levels of HP1γ and its phosphorylated Ser83 form are found in the cell lines, GC1 ... Voir le document complet
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