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The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion

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Academic year: 2021

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Figure

Fig. 1. Adipogenic conversion is delayed in Copr5 KO cells. (A) Phase contrast micrographs of EB generated from WT and KO ES cells at D0 (third day of treatment with 10 26 M retinoic acid) and at D4 and D21 after induction of EB adipogenic differentiation
Fig. 2. Dlk-1 upregulation in Copr5 KO Mefs is related to impaired recruitment of Prmt5 to the Dlk-1 promoter
Fig. 3. Modification of adipocyte cellularity in adipose tissue of Copr5 KO mice. (A) Histograms showing the total (left panel) and retroperitoneal fat (right panel) weights in WT and KO mice at 8 and 16 weeks of age (n55)

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