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Terminal differentiation

Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression.: MEF2A and MEF2D in c-Jun expression during macrophage differentiation

Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression.: MEF2A and MEF2D in c-Jun expression during macrophage differentiation

... Conditional deletions of MEF2C in the bone marrow resulted in no haematopoietic abnormalities, indicating that MEF2C is dispensable for steady state myelopoiesis [6-8]. However, Stehling et al. found that MEF2C ...

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p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodelling in osteoarthritis.

p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodelling in osteoarthritis.

... Figure 2 shows that p16 INK4a mRNA accumulates throughout the time course of an in vitro chondrogenesis from days 7 to 21 (Figure 2C). We therefore evaluated, during chondrogenesis, whether the expression of miR-24 could ...

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Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression

Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression

... MEF2 associates with p300 in HL60 macrophages In other cellular systems, it has been shown that MEF2 interacts with p300 HAT [20, 22-25]. To address this possibility, we first performed an immunolocalization of ...

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Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

... We next focused on the process of terminal differentiation. At D6, CD38 and CFSE detection allowed discrimination of three cell populations, hereafter referred to as P1, P2, and P3 ( Fig- ure 1 A). BrdU ...

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Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

... These residues are highly conserved, suggesting the possible con- servation of mTORC1-PASK signaling across metazoan species. Interestingly, similar to what is observed for several other mTORC1 substrates, the two ...

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The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes

The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes

... the differentiation processes in C2C12 myotubes, 33,38 whereas Ilk was a positive mediator of L6 myoblast ...of terminal myogenic differentiation, in accordance with the down reg- ulation of MyoG ...

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The C. elegans heterochronic pathway controls the timing of NAB/EGR-mediated terminal differentiation and the onset of adulthood

The C. elegans heterochronic pathway controls the timing of NAB/EGR-mediated terminal differentiation and the onset of adulthood

... Screens to identify factors that control seam cell exit from the cell cycle A screen for mutants in which the seam cells undergo extra divisions during adulthood. might[r] ...

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RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation

RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation

... Discussion Adipose tissue has a central role in metabolic regulations, partly due to its capacity to store lipids. Adipogenesis is controlled by several functionally coherent mechanisms, which are intricately coordinated ...

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Cpeb4-Mediated Translational Regulatory Circuitry Controls Terminal Erythroid Differentiation

Cpeb4-Mediated Translational Regulatory Circuitry Controls Terminal Erythroid Differentiation

... in terminal erythroid ...undergo terminal proliferation and differentiation into enucleated reticulocytes in vitro in a fashion that recapitulates terminal erythropoiesis in vivo (Ji et ...of ...

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CD8 T cell differentiation during immune responses

CD8 T cell differentiation during immune responses

... memory differentiation (Tbet and Eomes); receptors of molecules involved in the responsiveness to environmental cues: IL-10R, IL-12Rb1 and IL-21R; inhibitory molecules such as KLRG1 and PD1 (associated with ...

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Insider Trading With Product Differentiation

Insider Trading With Product Differentiation

... uct differentiation does not affect the results found in the literature on insider trading, concerning the effect of the financial market struc- ture on firms’ outputs, the revelation of information and the ...

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Iron-Catalyzed Dehydrogenative Borylation of Terminal Alkynes

Iron-Catalyzed Dehydrogenative Borylation of Terminal Alkynes

... ppm (see Figure S2). From a mechanistic point of view, as a Lewis acid, Fe(OTf) 2 should be able to activate the B-H bond, thus enhancing the electrophilic capacity of the boron center to react with acetylenic ...

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Air terminal building for Kuala Lumpur, Malaya

Air terminal building for Kuala Lumpur, Malaya

... The hot-humid climate of Malaya demands special considerations in design. Design criteria consist of the effective exclusion of heat, rain and humidity from within the building, [r] ...

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A bus terminal study for Tacoma, Washington

A bus terminal study for Tacoma, Washington

... Since virtually all bus traffic enters and leaves the central business district at the south along Pacific Avenue, the site selected requires of buses a minimum of circula[r] ...

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Bacteroid differentiation in Aeschynomene legumes

Bacteroid differentiation in Aeschynomene legumes

... 4. Differentiation of symbiotic nodule cells (A) A transversal section through the tip of a ...a differentiation zone were symbiotic cells are formed (II) and finally the upper part of the zone III with ...

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Optimisation de la consommation électrique du terminal à conteneurs est au port de Casablanca

Optimisation de la consommation électrique du terminal à conteneurs est au port de Casablanca

... Résumé Face à une forte augmentation de la facture en énergie électrique ces dernières années, les économies d’énergie ne permettent pas seulement d’amortir rapidement le surcoût issu de[r] ...

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Towards highly adaptable user-centric terminal architecture

Towards highly adaptable user-centric terminal architecture

... the terminal, named Terminal Station Management System (TSMS), undertakes the task of selecting the appropriate radio technology to be used for a service session by taking into account service and user ...

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Approches théoriques en codage vidéo robuste multi-terminal.

Approches théoriques en codage vidéo robuste multi-terminal.

... Abstract In this thesis, new robust video compression techniques are proposed for multi-terminal coding. We first compare four video multiple description coding schemes based on different time splitting patterns ...

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On production costs in vertical differentiation models

On production costs in vertical differentiation models

... Obviously, the introduction of a fixed production cost in a model with variable quality cost would not change firms’ quality choice. However, would the introduction of a production unit cost in models with fixed quality ...

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Genetic differentiation within and among refugia

Genetic differentiation within and among refugia

... oppositifolia, genetics studies do not allow the identification of nunatak survival in the Alps, presumably because any surviving nunatak population would have been swamped by colonization from main refugia (Holderegger ...

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