late-onset
Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases
... Methods and Results: We describe the clinical history of two patients that first showed OCD symptoms at an atypical age (>60 years). After several failed treatment attempts, they were hospitalized in our unit. Both ...
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Time-frequency relationships between heart rate and respiration: A diagnosis tool for late onset sepsis in sick premature infants
... of late onset sepsis in premature infants remains difficult because clinical signs are subtle and non-specific and none of the laboratory tests, including CRP and blood culture, have high predictive ...
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Diagnosis of Neonatal Late-Onset Infection in Very Preterm Infant: Inter-Observer Agreement and International Classifications
... * Correspondence: patrick.pladys@chu-rennes.fr; Tel.: +(33)-2-99-26-71-14 Abstract: Background: The definition of late-onset bacterial sepsis (LOS) in very preterm infants is not unified. The objective was ...
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Respiration signal as a promising diagnostic tool for late onset sepsis in premature newborns.
... Introduction Late-onset sepsis is defined as a systemic infection after the third day of life in neonates and, whatever the source of infection, there are nonspecific clinical ...[1]. ...
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Late onset deficits in synaptic plasticity in the valproic acid rat model of autism
... Prenatally treated VPA rats show behavioral deficits that share similarities with core autistic behaviors, in common with a small percentage of children that develop autism due to an exposure to VPA during pregnancy ( ...
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Difference in imaging biomarkers of neurodegeneration between early and late-onset amnestic Alzheimer's disease
... Frisoni, G.B., Testa, C., Sabattoli, F., Beltramello, A., Soininen, H., Laakso, M.P., 2005. Structural correlates of early and late-onset Alzheimer’s disease: voxel based morphometric study. J. Neurol. ...
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Late-onset neutropenia after treatment with rituximab for rheumatoid arthritis and other autoimmune diseases: data from the AutoImmunity and Rituximab registry
... of onset of neutropenia was approximately 5 months, in accordance with what has been observed in this previous studies in AIDs and in lymphoma (around 6 months 1–3 ), con firming their known late ...
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Long-term exposure to Myozyme results in a decrease of anti-drug antibodies in late-onset Pompe disease patients
... Federico Mingozzi 1,4 & French Pompe Registry Study Group # Immunogenicity of recombinant human acid-alpha glucosidase (rhGAA) in enzyme replacement therapy (ERT) is a safety and efficacy concern in the management of ...
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Late-onset polyucosan body myopathy in five patients with a homozygous mutation in GYG1
... A late-onset severe form of GSD IV, dubbed as adult polyglucosan body disease (APBD), is characterized by central leukodystrophy, peripheral neuropathy, neurogenic bladder, and inconsistently dementia [2, ...
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Whole genome sequencing of late-onset Alzheimer's disease patients from genetic isolate.
... common late-onset AD remain to be ...distantly-related late-onset AD patients from extra-large pedigree branches from genetically isolated Dutch population, described previously (Liu et al, Am ...
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Late-onset Rasmussen Encephalitis: A literature appraisal
... seizure onset and iii) a more favourable outcome is noted with 72% of good ...of late-onset RE, the outcome seems more favourable than in classical ...
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Early Detection of Late Onset Sepsis in Premature Infants Using Visibility Graph Analysis of Heart Rate Variability
... Cristhyne León, Guy Carrault, Patrick Pladys, and Alain Beuchée Abstract—Objective: This study was designed to test the diagnostic value of visibility graph features derived from the heart rate time series to predict ...
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The PREVENT study: a prospective cohort study to identify mid-life biomarkers of late-onset Alzheimer's disease.
... Methods and analysis: PREVENT is a prospective cohort study examining biomarker status at mid-life in at least 150 individuals genetically at high, medium or low risk of late-onset AD. Participants are ...
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Two Cases of Late-Onset Anti-NMDAr Auto-Immune Encephalitis After Herpes Simplex Virus 1 Encephalitis
... Dorcet et al. Late Onset Post-HSV-1 Autoimmune Encephalitis component and aggressiveness. Thus, the clinical presentation was typical for adult anti-NMDAr AIE ( 11 ) including post- infectious cases after ...
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Late-onset agoraphobia: general population incidence and evidence for a clinical subtype.
... having the first episode at age 65 or over. During the 4-year follow-up 11.2% of participants without agoraphobia at base-line were classified as cases giving an incident rate of 32 per 1000 person years. These 132 ...
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29 French adult patients with PMM2-congenital disorder of glycosylation: outcome of the classical pediatric phenotype and depiction of a late-onset phenotype
... a late-onset phenotype The diagnosis of PMM2-CDG in patients #11 and #14 of our sample shows that the absence of specific signs in childhood, or abnormal or subnormal intellectual func- tioning, does not ...
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Early-onset and late-onset Alzheimer’s disease are associated with distinct patterns of memory impairment
... 5 (Jacobs et al., 1994; Smits et al., 2012). Regarding memory, a relative sparing of memory in EOAD has been reported (Binetti et al., 1996; Smits et al., 2012), while several studies have found that LOAD patients ...
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Analysis of common and rare VPS13C variants in late-onset Parkinson disease
... The VPS13C gene is located within a risk locus for Parkinson disease (PD), reported in large genome-wide association studies (GWASs) of European population. 1,2 The single nu- cleotide polymorphism (SNP) reported in the ...
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Respective impact of implementation of prevention strategies, colonization with multiresistant bacteria and antimicrobial use on the risk of early- and late-onset VAP: An analysis of the OUTCOMEREA network
... estimation of two independent competing events: being extubated for more than 48 hours, death before occurrence of VAP. Conclusion Despite the limitations discussed above, our study showed important findings, ...
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Three Gene-Targeted Mouse Models of RNA Splicing Factor RP Show Late-Onset RPE and Retinal Degeneration
... Study of gene- targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP). Invest[r] ...
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