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Host cells

The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

... A B S T R A C T Mosquito-borne Zika virus (ZIKV) recently emerged in South Pacific islands and Americas where large epidemics were documented. In the present study, we investigated the contribution of the structural ...

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Dual Toxic-Peptide-Coding Staphylococcus aureus RNA under Antisense Regulation Targets Host Cells and Bacterial Rivals Unequally.

Dual Toxic-Peptide-Coding Staphylococcus aureus RNA under Antisense Regulation Targets Host Cells and Bacterial Rivals Unequally.

... Inducing the expression of the two membrane peptides trig- gers S. aureus death, possibly by generating pores. Except for SymE, all known type I toxins are small hydrophobic peptides acting as phage holins, forming pores ...

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Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

... eukaryotic host cell cycle and also hijack other key cellular processes such as those controlling the actin network and ...the host ubiquitin proteasome system through deamidation of ubiquitin or the ...

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Genome-scale analysis of Mycoplasma agalactiae loci involved in interaction with host cells

Genome-scale analysis of Mycoplasma agalactiae loci involved in interaction with host cells

... to host-pathogen ...and host- colonization, as well as a way to understand pathogenic processes involved in disease caused by these unconventional ...with host cells revealed 62 loci in the ...

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Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

... the host immune response, via inhibition of inflammatory pathways in dendritic cells of the gut-associated lymphoid ...the host cell cycle might slow down multiplication of intestinal progenitors to ...

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Colonisation of the Mucosae - Adherence Factors and their Interaction with Host Cells

Colonisation of the Mucosae - Adherence Factors and their Interaction with Host Cells

... in host cell adhe- ...the host cells respond as they would physiologically : recrui- ting cytoskeletal elements to the site of adhesion of the bacteria and attempting to strengthen the attachment to ...

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Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

... * mariana@ioc.fiocruz.br Abstract Several studies indicate that the activity of cruzipain, the main lysosomal cysteine peptidase of Trypanosoma cruzi, contributes to parasite infectivity. In addition, the parasitic ...

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Development of Disease - Bacterial Toxins and their Interaction with Host Cells

Development of Disease - Bacterial Toxins and their Interaction with Host Cells

... the host cell receptor, being internalised, crossing the lipid bilayer of the membrane of the endosomes and performing their intracellular toxic ...eukaryotic host cells, while the A subunit carries ...

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Ehrlichia's molecular tricks to manipulate their host cells

Ehrlichia's molecular tricks to manipulate their host cells

... cored cells, DC) attach to the surface of host target cells before entering by endocytosis ( ...the host cells, the bacteria develop within a membrane-bound vacuole where they create a ...

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Attachment of Chlamydia trachomatis L2 to host cells requires sulfation

Attachment of Chlamydia trachomatis L2 to host cells requires sulfation

... a host housekeeping ...the host cells and then kill ...mutant cells, showing that a defect in sulfation pathways in the host cell does not affect growth properties of Chlamydia per ...

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The N-terminal domain of the R28 protein promotes emm28 group A Streptococcus adhesion to host cells via direct binding to three integrins

The N-terminal domain of the R28 protein promotes emm28 group A Streptococcus adhesion to host cells via direct binding to three integrins

... R28 promotes direct binding to the cells. However, this is not the sole binding involved in the adhesion of GAS with hDSC as indicated by the fact that the mutant strain still adheres to the cells. GAS ...

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Selective recovery of RNAs from bacterial pathogens after their internalization by human host cells

Selective recovery of RNAs from bacterial pathogens after their internalization by human host cells

... Loren Dejoies 1,2 , Killian Le Neindre 1,2 , Sophie Reissier 2 , Brice Felden 2* & Vincent Cattoir 1,2,3* The aim of the study was to characterize the antimicrobial activity of clin[r] ...

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Variation in RNA Virus Mutation Rates across Host Cells

Variation in RNA Virus Mutation Rates across Host Cells

... the causes of this variability remain poorly understood. In addition to differences in intrinsic fidelity or error correction capability, viral mutation rates may be dependent on host factors. Here, we assessed ...

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Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli

Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli

... epithelial cells, which favors AIEC ...between host cells and AIEC is needed in order to combat AIEC ...Caco-2 cells and then spreads in epithelial cells to promote its survival, ...

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Localizing Genome Segments and Protein Products of a Multipartite Virus in Host Plant Cells

Localizing Genome Segments and Protein Products of a Multipartite Virus in Host Plant Cells

... individual host cells, and (ii) that the viral protein involved in the replication of all segments is often found within cells lacking the segment encoding it; suggesting that viral expression ...

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Metal economy in host-microbe interactions

Metal economy in host-microbe interactions

... overcome host resistance to infection, numerous mechanisms have been selected through the course of microbial evolution, in particular transporters that can feed the bacteria even at low metal concentration or, on ...

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Host cell responses induced by hepatitis C virus binding.: Host cell responses induced by HCV

Host cell responses induced by hepatitis C virus binding.: Host cell responses induced by HCV

... Xinhua Fang, Mirjam B Zeisel, Jochen Wilpert, Bettina Gissler, Robert Thimme, Clemens Kreutz, Thomas Maiwald, Jens Timmer, Winfried Kern,.. Johannes Donauer, et al.[r] ...

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Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor

Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor

... the host and the PI3K-Akt signaling pathway, in particular, has attracted much interest due to its central role in the regulation of apoptotic inhibition ...cancer cells that exhibit acti- vated Akt with ...

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Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model.

Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model.

... mononuclear cells; IV, intravenous; CB, cord blood, MSCs, mesenchymal stromal cells; GVHD, graft- ...T cells (CD4 + IL10 + ...Th17 cells, while BM-MSCs induced higher proportions of CD4 + IL10 ...

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Spodoptera frugiperda (Lepidoptera: Noctuidae) host-plant variants: two host strains or two distinct species?

Spodoptera frugiperda (Lepidoptera: Noctuidae) host-plant variants: two host strains or two distinct species?

... (115 kb) scaffold devoid of predictions for proteins of known function (except for transposable elements pro- teins), and Sfrugi11, which showed TRD in both crosses direction, is carried by a 10 kb genomic scaffold and ...

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