ATPase activity
Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
... their ATPase motors to kinetically avoid the formation of long- enough lived signal transducing units resulting from the binding of an illegitimate self ...the ATPase activity dis- cards any RNA ...
17
The ATPase Activity of Reptin Is Required for Its Effects on Tumor Cell Growth and Viability in Hepatocellular Carcinoma.: Requirement for Reptin ATPase activity in liver cancer
... the ATPase activity of Reptin is indeed required for the regulation of PIKK ...transcriptional activity of ATF2 ...its ATPase activity, and may rather depend on protein-protein ...
24
Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation.
... its unphosphorylated form, PLN inhibits SERCA activity and phosphorylation by various protein kinases: PKA, PKG, and Ca 2+ /Calmodulin kinase relieve this inhibition. Decreasing the inhibitory effect of PLN is ...
46
The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn
... Filamentous TorsinA is likely ATP bound. The resolution of our helical reconstruction is not high enough to directly deter- mine the nature of the bound nucleotide. We presume that the TorsinA filaments are nucleotide ...
13
La ségrégation du plasmide F d'Escherichia coli : régulation de l'activité ATPase de la protéine moteur de partition SopA
... of ATPase activation clarifies the role of ATP hydrolysis in the functioning of the Sop partition ...of ATPase by DNA alone is probably not significant in ...and ATPase activa- tion by SopB could ...
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Regulation of the type IV secretion ATPase TrwD by magnesium: implications for catalytic mechanism of the secretion ATPase superfamily.
... The kinetic parameters of ATP hydrolysis at steady-state rates reveal that physiological concentrations of Mg 2⫹ ( ⬃1 m M in bacterial cells (28)) down-regulate the ATP turnover of the enzyme by increasing the affinity ...
9
Mutations in V-ATPase assembly factors cause Congenital Disorder of Glycosylation (CDG) with autophagic liver disease
... in activity, (ii) increase of lysosomal pH and impairment of the activity of the lysosomal hydrolases, (iii) partial block in late steps of autophagic flux, (iv) accumulation of lipids inside the ...
225
Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex
... by ATPase assays and BLI binding studies. a Effect of LdcI on the ATPase activity of ...RavA. ATPase activity was measured at various pH values (ranging from 5 to 9) as described in ...
15
Involvement of the L6–7 Loop in SERCA1a Ca 2+ -ATPase Activation by Ca2+ (or Sr2+) and ATP
... optimize ATPase activity and stability; it allowed us to form lipid vesicles of 100 to 300 nm diameter which contained the reconstituted proteins, as shown by freeze fracture electron microscopy (Figure A ...
42
Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y (13)-mediated HDL endocytosis pathway on human hepatocytes.
... Fig. 4. The conversion of ADP to ATP in culture medium of HepG2 cell and primary human hepatocytes is dependant to NDPK activity. (A) ADP and other nucleotides were introduced alone or simultaneously to confluent ...
19
La libération des neuromédiateurs : le double jeu de la V-ATPase
... calciques et une augmentation brutale de la concen- tration cytosolique de calcium qui peut atteindre, dans des microdomaines situés sous les zones actives, des valeurs très élevées (200 µm et plus) [2] . Le neu- ...
5
La saturation des phospholipides membranaires induit un efflux de K+ et une activation de l’inflammasome NLRP3 dans des macrophages humains via l’intermédiaire de la Na, K-ATPase
... Conclusion En induisant une augmentation des niveaux de phospholipides saturés, le stéarate conduit à un efflux de K+ et une activation de l’inflammasome NLRP3 via l’inhibition de la Na, K-ATPase. L’oléate, en ...
1
Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche
... of the mitochondrial F O F 1 -ATPase aids to conserve Δψ m during infection to delay cell death of. 261[r] ...
25
SNARE, V-ATPase et neurotransmission
... tophore avait la capacité de libérer leur contenu, sous l’impulsion d’une élévation de la concentration calcique. Plus tard, le médiatophore s’est révélé être la sous-unité c du secteur V0 de la V-ATPase. Les ...
4
Normal mode based fitting of atomic structure into electron density maps: application to SR Ca-ATPase
... Two crystallographic conformations of Ca-ATPase have been used as starting points for our methods, 1EUL (Toyoshima et al., 2000) and 1IWO (Toyoshima and Nomura, 2002). Two other conformations, obtained by manual ...
11
Group Activity Selection Problem
... the activity that has been allocated to their group; thus, our model can be seen as a generalization of anonymous hedonic ...each activity and endowing it with suitable preferences (see Section ...real-life ...
12
PA1b Inhibitor Binding to Subunits c and e of the Vacuolar ATPase Reveals its Insecticidal Mechanism
... FIGURE 3. Electron microscopy of PA1b-bound V-ATPase. A, representa- tive classes of PA1b-streptavidin-HRP-bound V-ATPase in the absence of ATP. B, as A but in the presence of 2 m M Mg䡠ATP. The ...
12
Philosophy as activity
... Hadot proposes this following categorization of spiritual exercises, depending on their aims: learning to live (getting rid of passions, attention to the present, medit[r] ...
25
FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear.
... glass slides. All samples were washed in PBS, fixed in 4% paraformaldehyde for 10 minutes and rinsed with PBS. Cells were permeabilized using 0.3 % Triton X-100, rinsed with PBS and blocked with 3% BSA in PBS for 1 hour. ...
16
Sports, physical activity and academic performance : promoting physical activity among adolescents
... frequency of Participation in FunAction Activities for Boys and Girls Over the course ofthe 16 week intervention, 93 out of the 131 (71%) students in the intervention group participated [r] ...
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