[PDF] Top 20 In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal
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In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal
... masses of cells that resemble miniature organs. Liver organoids are obtained through isolation and expansion of stem and progenitor cells from hepatic stem cell niches to form small ... Voir le document complet
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DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease
... disruption of DEPTOR and activation of mTORC1 and S6K1. Our in vivo and in vitro data is the first to indicate that inhibition of mTORC1 by DEPTOR ... Voir le document complet
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Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy
... is a rising incidence of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with ...specific ... Voir le document complet
18
Magnetic resonance-based biomarkers in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
... ability of MRI-PDFF to detect longitudinal change in liver fat ...performed in adults and children with known or suspected NAFLD have shown that longitudinal change in MRI-PDFF ... Voir le document complet
10
Antiviral activity of brequinar against foot-and-mouth disease virus infection in vitro and in vivo
... immunosuppressive and antiproliferative drug, brequinar has been shown to be effective against allograft and xenograft rejection after transplantation [ 8 , 9 ...production and tumor growth [ 10 ]. ... Voir le document complet
6
Critical appraisal of STAT3 pattern in adult cardiomyocytes
... support a role for STAT3 in mouse cardiac mitochondria ...sensitivity, and toxicity of Stattic Stattic is a specific inhibitor of STAT3 [29] and has been used in ... Voir le document complet
26
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
... analysis and found that, although SNCA-OVX mice do not show pronounced whole-brain gliosis, the SN has increased levels of GFAP (glial fibrillary acidic pro- tein, astrocytes) and a shift ... Voir le document complet
15
Study of Developmental and Molecular Processes Sorbs1 Regulated by using a combination of in vitro and in vivo models
... Adhesion and Migration" took place in Robinson College Cambridge, United-Kingdom of 20-23 June 2016 ...field of expertise is to study the dynamic of the cytoskeleton in ... Voir le document complet
2
In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.
... activity of insulin (data not shown). These results were not in favour of a cytotoxic effect of BrPal on ...adipocytes. In order to determine, whether BrPal altered adipocyte α2− ... Voir le document complet
25
Hepatocytic Differentiation Potential of Human Fetal Liver Mesenchymal Stem Cells: In Vitro and In Vivo Evaluation
... incubated in 2 mL of buffer ...glucose-6-phosphate and 2.4 mM nitric lead at 37 ∘ C in humidified atmosphere containing 5% CO 2 ...is in these conditions transformed into glucose ... Voir le document complet
14
Antiviral activity of merimepodib against foot and mouth disease virus in vitro and in vivo.
... Foot-and-mouth disease (FMD) is one of the most highly contagious viral diseases of cloven-hoofed animals that has significant economic effects in affected countries ( Moraes et ...that ... Voir le document complet
7
Investigating in vitro digestion of food models to explain in vivo micronutrient bioavailability
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ... Voir le document complet
17
Critical points in coupled Potts models and critical phases in coupled loop models
... is a jump singularity in the derivative f ′ (λ) at some λ = λ 0 (L), signaling a first-order phase ...termination of the critical phase. The existence of this first-order phase ... Voir le document complet
24
In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A
... VWD models). 4 days after HGT blood was collected and VWF assays performed on mouse ...profile of plasmatic VWF in 2% agarose gels in mice co-expressing VWF-WT & VWF-DEL, VWF-WT ... Voir le document complet
16
In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice
... USA) and Bioanalyzer DNA 7500 (Agilent, California, ...from a pooled human DNA (Promega, Charbonnieres, France) was used as a ...ng of tumor and reference DNAs were fragmented with AluI ... Voir le document complet
22
A first appraisal of prognostic ocean DMS models and prospects for their use in climate models
... that models are comparable in terms of their ability to simulate Chl a (see Figure ...1 In terms of DMS, all the models reproduce the pattern of higher DMS during ... Voir le document complet
14
Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?
... study of probiotics in treatment of non-alcoholic fatty liver disease-- 《Chinese Journal of Gastroenterology and ... Voir le document complet
38
Nonalcoholic fatty liver disease and obstructive sleep apnea
... that a sleep study should be systematically performed in NAFLD patients to detect OSA, even in pauci-symptomatic ...results of a recent study that showed that in newly diagnosed ... Voir le document complet
28
Rôle du régulateur du cycle cellulaire p16INK4a dans le développement du diabète de type 2 et dans les maladies métaboliques du foie gras ou NAFLD (Non-Alcoholic Fatty Liver Disease) : rôle de p16INK4a dans le contrôle de la néoglucogenèse hépatique et dans le développement de la stéatose hépatique non alcoolique.
... coenzyme A via l’acyl CoA synthetase est nécessaire pour permettre le transport des AGs à travers la membrane ...y a synthèse d’ATP et d’acétyl-CoA, ce dernier est dirigé vers le cycle de Krebs pour fournir ... Voir le document complet
117
Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson’s disease
... investigated in this study are presented in Figure ...provided in the Supplementary Material (SM); with the description of the kinetic-metabolic model (Table S1), fluxes’ kinetic formulation ... Voir le document complet
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