[PDF] Top 20 Surface properties of biomimetic nanocrystalline apatites; applications in biomaterials

... Member of the CIRIMAT Carnot Institute in Toulouse, France (“Phosphates, Pharmaco- technics, Biomaterials” research ...Ph.D. in Materials ...thermochemistry of natural or synthetic ... Voir le document complet

... interactions of molecules with apatites, in 1984, under the supervision of ...work in the field of bio- materials on continuing his collaboration with ...head of the ... Voir le document complet

... therefore of high interest [302] . In this way, the molecules can both sustain their biological activity for a considered period of time and support the mechanical properties of the ... Voir le document complet

... Abstract Nanocrystalline apatites are major constituents of hard tissues, and attempts are made worldwide to pre- pare synthetic ...impact of synthesis/ postsynthesis parameters is often ... Voir le document complet

... redispersion of the particles The above findings indicate that some alterations of the suspensions physico-chemical properties, especially in terms of viscosity and/or mean particle ... Voir le document complet

... biomedical applications of nanocrystalline apatites ...and surface functionalization Materials can interact with biomolecules as well as with living systems and these interactions can ... Voir le document complet

... phosphate apatites have received a recurrent attention for the last twenty years mainly for their use as biomaterials related to compositional similarity with bone mineral and biological ...various ... Voir le document complet

... University of Toulouse, UMR CNRS/INPT/UPS 5085, Toulouse, France ...Abstract. Nanocrystalline apatites constitute the mineral part of hard tissues, and can be reproduced ...impact of ... Voir le document complet

... indication of the coverage of the surface by the molecule), ‘‘a’’ is the pre-exponential factor, ‘‘m’’ is the order of the desorption kinetics, and E d is the activation energy of the ... Voir le document complet

... part of bone, synthetic calcium-deficient apatites prepared in close-to-biological conditions (low temperature, physio- logical pH) are constituted of nanocrystals involving an apatitic core ... Voir le document complet

... third of all PO 4 3! ions are replaced by HPO 4 2! and CO 3 2! bivalent ...hydrated surface layer containing bivalent labile ions, offering a basis for functionalization with bioactive mineral ions or ... Voir le document complet

... those of bone nanocrystals, which make them very promis- ing biomaterials for the preparation of highly bioactive ceramics [21] ...Non-stoichiometric nanocrystalline apatite-based biomate- ... Voir le document complet

... fluoridation of plasma-sprayed HA coatings can be obtained by treatment of the raw coating in a fluoride-containing solution (KF : ...addition of phosphate (F/P = 1/3) in the solution ... Voir le document complet

... Nanocrystalline apatites Surface exchange Biomimetism The surface activation of calcium phosphate-based biomaterials for bone repair is an emerging route for improving bone ... Voir le document complet

... redispersion of the particles The above findings indicate that some alterations of the suspensions physico-chemical properties, especially in terms of viscosity and/or mean particle ... Voir le document complet

... association of apatitic tridimensional constructs with biologically relevant ions or drugs, including anticancer agents, has also been pointed out ( Lebugle et ...the nanocrystalline character of ... Voir le document complet

... association of a drug with mineral bone repair scaffolds is not a straightforward task, in particular due to the relative fragility of the organic molecules (usually heat- sensitive) constituting the ... Voir le document complet

... effects of synthesis parameters (maturation time, temperature and pH) on the physico-chemical characteristics of the starting apatite ...presence of non-apatitic chemical environments, extent ... Voir le document complet

... the surface ions of the hydrated layer; however, these capa- bilities have rarely been used in materials ...poration of small molecules in apatite has been occasionally reported [39,40] ... Voir le document complet

... Adsorption of organic molecules Very few studies have been done on the adsorption of organic molecules on well characterised nanocrystalline apatites [33,34] ...increase of the affinity ... Voir le document complet