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[PDF] Top 20 Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example.

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Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example.

Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example.

... Implications of the hypothesis The candidate pathway-based strategy described here was able to select a large number of candidate genes to be tested ... Voir le document complet

6

Gene–environment interactions in the study of asthma in the postgenomewide association studies era

Gene–environment interactions in the study of asthma in the postgenomewide association studies era

... the candidate and the “agnostic” approach of GWAS is provided by the pathway-based approach, in which several genes related to the biological pathways of interest are ...studied. ... Voir le document complet

25

Asthma and genes encoding components of the vitamin D pathway

Asthma and genes encoding components of the vitamin D pathway

... calculations for the four study populations were recently described [42]. Gene-gene interactions were evaluated for asthma and atopy using a multilocus analysis method ... Voir le document complet

21

GAD2 on chromosome 10p12 is a candidate gene for human obesity.

GAD2 on chromosome 10p12 is a candidate gene for human obesity.

... primary based on case-control studies in French Caucasian adult patients, a population still protected against massive obesity, as its prevalence is three to five times lower compared to the United ... Voir le document complet

12

Rapid identification of an Arabidopsis NLR gene as a candidate conferring susceptibility to Sclerotinia sclerotiorum using time‐resolved automated phenotyping

Rapid identification of an Arabidopsis NLR gene as a candidate conferring susceptibility to Sclerotinia sclerotiorum using time‐resolved automated phenotyping

... that A. thaliana NLR gene LAZ5 (At5g44870), but not its close relative constitutive shade avoidance 1 (CSA1), confers susceptibility to ...rum. For this, we precisely assessed the kinetics of ... Voir le document complet

16

Neural Evidence for Adaptive Strategy Selection in Value-Based Decision-Making

Neural Evidence for Adaptive Strategy Selection in Value-Based Decision-Making

... feedback. An alternative solution is to generate decision strategies that appear ade- quate for solving the ...selecting a particular strategy and evaluating its adequacy based on the ... Voir le document complet

13

High Resolution Melting and Insertion Site-Based Polymorphism Markers for Wheat Variability Analysis and Candidate Genes Selection at Drought and Heat MQTL Loci

High Resolution Melting and Insertion Site-Based Polymorphism Markers for Wheat Variability Analysis and Candidate Genes Selection at Drought and Heat MQTL Loci

... all candidate genes located within a +/−20 kb window to the wheat chromosome 4A ISBP ...markers. Genes with differences on their expression are shown in bold and DE genes are indicated ... Voir le document complet

29

Using 3D sound for providing 3D interaction in virtual environment

Using 3D sound for providing 3D interaction in virtual environment

... use of gestural interaction for modifying the position and other characteristics of 3D sound ...audio interaction capabilities: Handy Sound and ...use of 3D sound for ... Voir le document complet

12

Potential candidate genes for improving Rice disease resistance

Potential candidate genes for improving Rice disease resistance

... Most of the elements involved (receptors, regulators, transcription factors, and defense genes) are well conserved across ...species. For example, the NPR1 gene is a central ... Voir le document complet

17

Optimization of multi-environment trials for genomic selection based on crop models

Optimization of multi-environment trials for genomic selection based on crop models

... variability of the NRMSE, which can be explained by the important year effect on climatic ...was for example important for the OptiMET MET, which NRMSE could almost double from one year to ... Voir le document complet

19

Genes involved in the metabolism of fatty acids and risk for Crohn's disease in children: a candidate gene study

Genes involved in the metabolism of fatty acids and risk for Crohn's disease in children: a candidate gene study

... end-products of AA metabolism are dependent on the specific cell, and the activity, expression and amounts of these ...production of these derivatives and their action in the body are collectively ... Voir le document complet

210

Detecting directional and epistatic selection from candidate genes: methodological improvements and a case study of European beech

Detecting directional and epistatic selection from candidate genes: methodological improvements and a case study of European beech

... STUDY OF Fagus sylvatica • sampling at a short spatial scale with sharp environmental differences • SNPs from candidate genes potentially involved in climate response See more details in: K ... Voir le document complet

2

Localisation of two candidate genes for mental retardation using a YAC physical map of the Xq21.1-21.2 subbands

Localisation of two candidate genes for mental retardation using a YAC physical map of the Xq21.1-21.2 subbands

... usually choroideremia (CHM), but sometimes both CHM and deafness (DFN3).125-7 Other strong evidence for the presence of a gene or genes in Xq21 involved in mental retardation conditions [r] ... Voir le document complet

6

A strategy for bounding attributable risk: a lung cancer example.

A strategy for bounding attributable risk: a lung cancer example.

... One of the important lessons we have learned about applied policy analysis is that methods pro- posed in theory need to be refined through applica- ...to a real problem we have discovered issues that ... Voir le document complet

4

TIGRESS: Trustful Inference of Gene REgulation using Stability Selection.

TIGRESS: Trustful Inference of Gene REgulation using Stability Selection.

... variants of these scores with more general non-increasing functions φ, not only for GRN inference but also more generally as a generic feature selection ...achieves a similar ... Voir le document complet

21

Potential benefits from multitrait evaluation - an example in selection for mastitis resistance based on somatic cell score and udder conformation. A simulation study

Potential benefits from multitrait evaluation - an example in selection for mastitis resistance based on somatic cell score and udder conformation. A simulation study

... out of correlated traits. The most common approach is to use a selection index where the trait we want to select on is MR (or udder health), and the information vector contains the estimated breeding ... Voir le document complet

7

A Unified Model for Interaction in 3D Environment

A Unified Model for Interaction in 3D Environment

... 5.3 Environment 2: Simultaneous manipulation of several objects If the implementation of the environment presented in Section ...principles of our model, this single test is not ... Voir le document complet

8

[Genetics of asthma and atopy: how many genes?]

[Genetics of asthma and atopy: how many genes?]

... l'asthme a été très discutée dans la ...une interaction gène- environnement ...immunologiques a mis en évidence six interactions (quatre de ces interactions étant plus vraisemblables après prise en ... Voir le document complet

13

Connecting strategy and system dynamics: an example and lessons learned

Connecting strategy and system dynamics: an example and lessons learned

... outcomes of those investments vary across different types of capabilities, thus shifting investments could lead to worse-before-better reference mode observed in maintenance (Zuashkiani, Rahmandad, and ... Voir le document complet

21

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en fr Gene-environment interaction in oral cleft etiology INTERACTIONS GENE-ENVIRONNEMENT DANS L'ETIOLOGIE DES FENTES ORALES

... L’interprétation de ces résultats doit être finalement menée avec prudence et, si un risque existe, il pourrait être attribué de préférence à la présence d’expositions multiples incluant des solvants chlorés et ... Voir le document complet

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