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[PDF] Top 20 Evaluation of the association between common genetic variants and breast cancer risk

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Evaluation of the association between common genetic variants and breast cancer risk

Evaluation of the association between common genetic variants and breast cancer risk

... 20% of the inherited susceptibility, intermediate-risk alleles in DNA-repair genes increase this proportion by ~5% [6-18], and common lower-risk alleles, of which ... Voir le document complet

519

Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

... associations between polymorphisms in the genes that code for GNRH1 or its receptor and either cir- culating ovarian sex hormones or breast cancer ...influence of SNPs in these ... Voir le document complet

9

No evidence that common genetic risk variation is shared between schizophrenia and autism

No evidence that common genetic risk variation is shared between schizophrenia and autism

... families and procedures had approval from institutional review boards. We used the same schizophrenia score allele set previously described by the ISC [Purcell et ...subset of 74,062 SNPs was ... Voir le document complet

11

Association between serum trans-monounsaturated fatty acids and breast cancer risk in the E3N-EPIC Study.

Association between serum trans-monounsaturated fatty acids and breast cancer risk in the E3N-EPIC Study.

... increase the risk of invasive breast ...although the mean population intake of trans- fatty acids from hydrogenated fats fell to around 1 g per day in 2005, daily intakes ... Voir le document complet

11

Genetic variants involved in specialized DNA replication and their relation with breast cancer risk, disease progression and patient prognosis

Genetic variants involved in specialized DNA replication and their relation with breast cancer risk, disease progression and patient prognosis

... to cancer progression in this patient ...analyzed and the correlation between genotype and relevant clinical variables for breast cancer prognosis will be ... Voir le document complet

2

Association between hereditary predisposition to common cancers and congenital multimalformations

Association between hereditary predisposition to common cancers and congenital multimalformations

... favoring cancer at adulthood seemed to improve fertility and limit ...frequency of congenital malformation could be evidenced among cancer-prone ...members) of the comprehensive ... Voir le document complet

10

Dietary Factors Impact on the Association between CTSS Variants and Obesity Related Traits.

Dietary Factors Impact on the Association between CTSS Variants and Obesity Related Traits.

... experienced the greatest degree of unexplained annual weight gain during follow-up (with an average duration of 6–8 ...using the residuals from a regression model of annual weight ... Voir le document complet

11

Association between Radiotherapy and Risk of Cancer Associated Venous Thromboembolism: A Sub-Analysis of the COMPASS-CAT Study

Association between Radiotherapy and Risk of Cancer Associated Venous Thromboembolism: A Sub-Analysis of the COMPASS-CAT Study

... Limitations of this analysis include the variability of patients, related to the multina- tional nature of the study with patients included across six different countries which ... Voir le document complet

11

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

... Of the eight SNPs investigated, the strongest associa- tion was found between SNP rs10771399 at 12p11 and breast cancer risk for BRCA1 mutation ...BRCA1 ... Voir le document complet

17

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

... Mourits; The Netherlands Foundation for the detection of hereditary tumours, Leiden, the Netherlands: Hans ...For the kConFab study, Amanda B. Spurdle and Georgia Chenevix-Trench ... Voir le document complet

13

Exploring the link between MORF4L1 and risk of breast cancer.

Exploring the link between MORF4L1 and risk of breast cancer.

... Given the evidence across biological levels and species models, we hypothesized that perturbation of MRG15 function through genetic mutations or common alleles might be at the ... Voir le document complet

15

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

... While genetic association studies have identified alleles that confer disease risk, little is known about how these genetic variants contribute to disease through their effects on ... Voir le document complet

20

Association between melanocytic nevi and risk of breast diseases: The French E3N prospective cohort.

Association between melanocytic nevi and risk of breast diseases: The French E3N prospective cohort.

... had breast cancer, and about half a million women died from the ...disease. Breast cancer begins when cells in the breast acquire genetic changes that allow ... Voir le document complet

13

Progestins and progesterone in hormone replacement therapy and the risk of breast cancer.

Progestins and progesterone in hormone replacement therapy and the risk of breast cancer.

... Relative risk (RR) or odd ratios (OR) of breast cancer in long term HRT ...progestins and (20%) MPA; (*) only 19-Nortestosterone-derived progestins; () mainly ... Voir le document complet

19

Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy

Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy

... for the 185 PML cases using the ACE Exome sequencing service by Personalis (Menlo Park, ...for the TGP exome data, we used the DV caller (39) for variant calling in the WES data ...to ... Voir le document complet

15

[Hormone replacement therapy in menopause and risk of breast cancer]

[Hormone replacement therapy in menopause and risk of breast cancer]

... de cancer du ...de cancer du sein plus élevé chez les femmes ayant utilisé un THS que chez les ...de cancer du sein associée à la prise d‘un traitement combinant œstrogène et progestatif a un impact ... Voir le document complet

15

Oral progestagens before menopause and breast cancer risk.

Oral progestagens before menopause and breast cancer risk.

... examined the relationship between use of progestagen-only before menopause (except for mini-pills) after the age of 40 and invasive breast cancer risk in 73 ... Voir le document complet

8

Analysis of the association between CDH2 gene polymorphism and osteoarthritis risk

Analysis of the association between CDH2 gene polymorphism and osteoarthritis risk

... analyzed the association between OA and SNP loci in the case group and in the control ...in the OA group were divided into mild group (II) and severe group ... Voir le document complet

8

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

... Utrecht, the Netherlands, 27 Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands, 28 Department of Clinical Genetics, VU University Medical Center, Amsterdam, ... Voir le document complet

19

Association between common mental disorder and obesity over the adult life course.

Association between common mental disorder and obesity over the adult life course.

... for the total cohort and separately for men and women. For the analyses of the prospective data, which are structured such that measurement times (observations) are nested within ... Voir le document complet

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