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[PDF] Top 20 Autophagy: A protective mechanism in response to stress and inflammation.

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Autophagy: A protective mechanism in response to stress and inflammation.

Autophagy: A protective mechanism in response to stress and inflammation.

... reaction in response to pathogens and anti- inflammatory reaction to limit the tissue ...factors and cytokines which modulate vascular permeability, leukocyte infiltration ... Voir le document complet

22

PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress

PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress

... chambers and maintained in culture as long as the flow- subjected ...analysis and antibodies. Cells in micro- slides were washed twice with ice-cold PBS and lysed in ice with 150 ... Voir le document complet

10

Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite

Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite

... According to our data, it is tempting to speculate about a possible impact of contemporaneous liver in flammatory episodes on malaria transmission and disease progression in ... Voir le document complet

17

Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress

Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress

... argon in the present study was rather ...14,15 In fact, argon is believed to directly activate intracellular pathways that control the expression of anti-apoptotic proteins such as ...neuroprotective ... Voir le document complet

10

A CREB3–ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

A CREB3–ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

... found in humans is further divided into three classes based on amino acid similarity: class I is composed of ARF1 and ARF3, ARF4 and ARF5 belong to class II, and class III contains ... Voir le document complet

28

Interplay between autophagy and the primary cilium : Role in mechanical stress integration

Interplay between autophagy and the primary cilium : Role in mechanical stress integration

... Motile and primary cilia are microtubule-based structures located at the cell surface of many cell ...motility to integration of mechanical and chemical signaling from the ...environment. In ... Voir le document complet

200

Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D

Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D

... inflammatory response in adipose tissue during obesity 4-6 ...translation, and their function depends on the complementarity of sequence with the target mRNA 7 ...involved in adipocyte ... Voir le document complet

24

Subversion of autophagy in adherent invasive<em> Escherichia coli</em>-infected neutrophils induces inflammation and cell death

Subversion of autophagy in adherent invasive<em> Escherichia coli</em>-infected neutrophils induces inflammation and cell death

... of autophagy by nutrient starvation (HBSS) or rapamycin treatment eliminated mycobacteria in macrophages [27], and AIEC in epithelial cells [6] and in macrophages ...upregulating ... Voir le document complet

11

The regulatory effects of circulating normal immunoglobulins on autophagy and Th17 response

The regulatory effects of circulating normal immunoglobulins on autophagy and Th17 response

... been a major research interest in potential inhibitors of the RORγt/Th17 ...reported to inhibit the transcriptional activity of RORγt ...(210) and inhibited IL- 17 production of T-cells from ... Voir le document complet

239

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

... as a function of the axonal perimeter shows that the alteration of myelin thickness is more severe in small caliber axons ...). In addition, we also reveal that this category of smaller axons appears ... Voir le document complet

14

Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells

Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells

... cell inflammation is an important contributor to atherosclerosis [ 34 ], notably during aging [ 35 – 37 ...of inflammation was also reported in the atherosclerotic lesions of patients with ... Voir le document complet

17

Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers

Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers

... Despite a growing list of IRES-containing mRNAs, the mechanism of internal initiation is still poorly ...identified in conditions of inhibited cap-dependent initiation, the cap-binding protein eIF4E ... Voir le document complet

29

O-GlcNAcylation and inflammation: a vast territory to explore

O-GlcNAcylation and inflammation: a vast territory to explore

... Unexpectedly, in this study, glucosamine induced a decrease in NFκB ...OGT and NFκB ( 72 ...cRel in BV2 microglial cells, showing glucosamine inhibition of LPS- induced cRel-OGT ... Voir le document complet

9

Fluid Shear Stress: a modulator of the vasculo-protective effects of polyphenols?

Fluid Shear Stress: a modulator of the vasculo-protective effects of polyphenols?

... ‐ To analyse the response of endothelial cells to physiological relevant concentrations of polyphenols under shear stress conditions ‐ To evaluate how shear stress modulates the ... Voir le document complet

15

Stress neuromediators are key regulators of the intestinal barrier: Link to inflammation and cancer: Stress neuromediators regulate the intestinal barrier

Stress neuromediators are key regulators of the intestinal barrier: Link to inflammation and cancer: Stress neuromediators regulate the intestinal barrier

... Jankowski and co-wokers have demonstrated that deregulation of E- and P- cadherin correlates with the progression of human colitis ...permeability in CD [241-244] which is most likely attributed ... Voir le document complet

27

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol.

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol.

... central in the integrated stress response (Kroemer et ...implicated in the control of autophagy, including the mammalian target of rapamycin (mTOR) ...as a sensor for cellular ... Voir le document complet

43

Autophagy-lysosomal pathway in response to fasting/refeeding in C2C12 myotubes

Autophagy-lysosomal pathway in response to fasting/refeeding in C2C12 myotubes

... Mechanisms and consequences of human adipose tissue inflammation D lacasa Centre de Recherche des Cordeliers, Universite´ Pierre et Marie Curie-Paris6, ICAN Institut Cardiome´tabolisme et Nutrition, Paris, ... Voir le document complet

122

Bacillus sphaericus binary toxin elicits host cell autophagy as a response to intoxication

Bacillus sphaericus binary toxin elicits host cell autophagy as a response to intoxication

... molecular mechanism by which ...Culex and Anopheles is still undefined [3]. To date, the nature and the sequence of the cellular events leading to larval death remain unknown, ... Voir le document complet

13

Identification of autophagy genes in Ciona intestinalis : A new experimental model to study autophagy mechanism

Identification of autophagy genes in Ciona intestinalis : A new experimental model to study autophagy mechanism

... implicated in physiological processes (i.e. tissue homeostasis, development, and dangerous cell elimination) and its deregulation is observed in many pathologies ...is a degradation of ... Voir le document complet

32

Inflammation intestinale et stress du réticulum endoplasmique - Un lien génétique

Inflammation intestinale et stress du réticulum endoplasmique - Un lien génétique

... 900 M/S n° 11, vol. 24, novembre 2008 lisation de l’UPR la plus conservée au cours de l’évolution. Elle possède dans son domaine cytosolique une activité kinase et une activité endoribonuclé- ase dont l’activation lors ... Voir le document complet

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