Opioid receptors
Delta Opioid Receptors: Learning and Motivation
... Delta opioid receptors and place/associative learning Abundant expression of DOR in the hippocampus and tightly connected structures such as subiculum, entorhinal cortex or septal area( Figure 1 ) points ...
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Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice
... mu receptors expressed by cell types other than primary ...delta opioid receptors in these same neurons [15], and differ from those obtained with the ...CB1 receptors, that showed increased ...
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Mu and delta opioid receptors oppositely regulate motor impulsivity in the signaled nose poke task.
... mu-opioid receptors were significantly better at inhibiting a motor response, whereas mice lacking the delta-opioid receptor were significantly ...
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In vivo neuronal co-expression of mu and delta opioid receptors uncovers new therapeutic perspectives.
... mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical ...delta- opioid receptors uncover G protein-coupled receptor dynamics in ...
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Agonist binding of human mu opioid receptors expressed in the yeast Pichia pastoris: Effect of cholesterol complementation
... recombinant receptors used to obtain 3D- structures were expressed with truncated and modified forms ...mu opioid receptor that was crystallised in 2012 (Manglik, Kruse et ...membrane receptors must ...
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The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
... to opioid receptors and inhibits their signaling and trafficking in ...Venus-tagged opioid receptors dOR, kOR and mOR or ...CXCR4 receptors (see Figure 4 ), showing that close proximity ...
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en fr Mu opioid receptors in the habenula : dissecting reward and aversion in addiction Récepteurs Mu aux opioïdes dans l'habénula : récompense et/ou aversion dans l'addiction
... mu opioid receptors (MORs), a receptor classically associated to drug and natural rewards while little is known about MOR contribution to aversive ...MOR-mediated opioid tone normally reduces place ...
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en fr Role of intestinal gluconeogenesis and mu-opioid receptors in the metabolic benefits of gastric bypass in mice Rôle de la néoglucogenèse intestinale et des récepteurs mu-opioïdes dans les effets bénéfiques du by-pass gastrique chez la souris
... J’ai plus particulièrement étudié les relations entre la production intestinale de glucose et les effets bénéfiques du by-pass duodéno-jéjunal, une chirurgie de l’obésité qui reproduit[r] ...
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Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake.
... Zhang, J., Frassetto, A., Huang, R. R., Lao, J. Z., Pasternak, A., Wang, S. P., Metzger, J. M., Strack, A. M., Fong, T. M., and Chen, R. Z. (2006). The mu-opioid receptor subtype is required for the anorectic ...
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Reward processing by the opioid system in the brain.
... Briefly, opioid receptor agonists injected directly into the MPOA inhibited or delayed masculine copulatory activity in rats, except for low doses of morphine or dynorphin-A-(1—13) (reviewed in ...Conversely, ...
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Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design
... opioid receptors could be evoked by biased receptor signalling, arguably contributing to significant differences in efficacy profiles between commonly-used μ opioid receptor agonist drugs 67 ...
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Activities of neuropeptide FF receptors: in vitro anti-opioid and in vivo anti-depressant effects
... NPFF receptors activity on Ca 2þ transients induced by ...NPFF receptors on mice DRN prefer to associate with G i/o proteins, with no or very limited proportion of G q protein ...anti- opioid ...
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In vivo delta opioid receptor internalization controls behavioral effects of agonists.
... Methods and Findings: In this study, we used knock-in mice expressing functional fluorescent delta opioid receptors (DOR- eGFP) in place of the native receptor to correlate receptor localization in neurons ...
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Mu-opioid antagonism in the treatment of cannabis use disorder
... NTX is an antagonist of mµ-opioid receptors. Preclinical studies showed bi-directional interaction between endocannabinoids and the endogenous opioid peptides 5 . In turn, opioid antagonists ...
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Buprenorphine/naloxone as a promising therapeutic option for opioid abusing patients with chronic pain: reduction of pain, opioid withdrawal symptoms, and abuse liability of oral oxycodone.
... Methods Participants All of the participants were currently under the care of a physician for mild to moderate chronic, non-malignant pain. They were also required to meet DSM-IV criteria for opioid dependence, ...
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Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality
... USA opioid epidemic is far from hitting France and Europe more broadly, which con- trast strongly with America in terms of legislation, practice, and drug consumption patterns (Weisberg et ...of opioid ...
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Willingness to receive intravenous buprenorphine treatment in opioid-dependent people refractory to oral opioid maintenance treatment: results from a community-based survey in France
... to opioid use, 58% mainly injected oral buprenorphine, 15% heroin, 17% oral morphine sulfate and 10% other pre- scription opiates (methadone, oxycodone, codeine and ...other opioid injectors, these values ...
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Electrophysiology of ionotropic GABA receptors
... Membrane resistivity (ρ) is equal to the transmembrane potential (ΔE) divided by the intensity (I) of the current passing through a unit of membrane surface: ρ = ΔE × S/I (where S is the area of the membrane domain). The ...
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Death receptors as targets in cancer
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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Chemokine receptors in allergic diseases
... increases their transendothelial migration (49). Finally, the expression of CX3CR1 by Th2 cells stimulated their survival and their retention within the airways (19). Given the complexity and the redundancy of this ...
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