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endothelial cell-derived microparticles

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases.

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases.

... and endothelial damage associated with EMP production are encountered in similar diseases, we decided to explore these interactions, as well as the capacity of EMP to modulate PDC ...PDC cell line ...PDC ...

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VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells

VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells

... in endothelial cells To investigate β-catenin activation, we established a co-culture of eGFP-E4+ECs, with two ovarian cancer cell lines Skov3 and APOCC (ovarian cancer cell line derived in ...

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Cell-derived microparticles: a new challenge in neuroscience.

Cell-derived microparticles: a new challenge in neuroscience.

... Microparticles (MPs) are membrane fragments shed by cells activated by a variety of stimuli including serine proteases, inflammatory cytokines, growth factors and stress ...leukocytes, endothelial cells ...

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Microparticles and Fibrinolysis

Microparticles and Fibrinolysis

... MPs derived from human microvascular endothelial cells after stimulation with tumor necrosis factor- ...primary endothelial cells from different organs (kidney: renal artery; heart: heart coronary ...

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Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.

Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.

... between endothelial cells and circulating monocytes are responsible for microvasculature dysfunction contributing to the pathogenesis of this ...whether microparticles derived from activated ...

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Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function.

Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function.

... of cell types in response to inflammatory mediators ...different cell types through the interaction of proteins exposed in their surface with their cell counter- receptors ...as endothelial ...

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Atomic Force microscopy reveals a role for endothelial cell ICAM-1 expression in bladder cancer cell adherence

Atomic Force microscopy reveals a role for endothelial cell ICAM-1 expression in bladder cancer cell adherence

... cancer cell lines, during similar ...cancer cell from the EC. The detachment force is supported by the cell deformability, but also by the number and strength of adhesive bonds formed between ...

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Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

... vascular endothelial permeability has remained poorly ...tumour cell extravasation during haematogenous ...on endothelial integrity in large part through SPARC ...vivo endothelial permeability ...

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Translational implications of endothelial cell dysfunction in association with chronic allograft rejection

Translational implications of endothelial cell dysfunction in association with chronic allograft rejection

... Cell Intrinsic Regulation of Microvascular Stability within an Allograft Understanding the regulation of key signals within the EC that are critical for microvascular stability may pave the way for the development ...

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Capacity of curcumin, a polyphenol presenting vasculo-protective properties, to modulate secretion and miRNA and protein profiles of endothelial microparticles

Capacity of curcumin, a polyphenol presenting vasculo-protective properties, to modulate secretion and miRNA and protein profiles of endothelial microparticles

... the microparticles isolated from the culture medium 2) Enumeration of microparticles in culture medium using flow cytometry Electron microscopy revealed microparticles with size ranging from ...

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Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia

Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia

... on endothelial cells of mice carrying either transgenic or control embryos, we discovered significant alterations of gene networks involved in inflammation, cell cycle, and cardiac ...the endothelial ...

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New methodological strategies in haematology using cell-derived microvesicles

New methodological strategies in haematology using cell-derived microvesicles

... parental cell, thus constituting a disseminated dynamic pool of bioactive effectors or messengers, as do- cumented by several in vitro studies [17 25, 19 22, 20 ...

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Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset

Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset

... SASP is characterized by the production of several bioactive fac‐ tors such as growth factors, pro‐inflammatory cytokines, chemok‐ ines and proteases but the fine composition of the secreted factors appears to be ...

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Comparative analysis of nanosystems' effects on human endothelial and monocytic cell functions.

Comparative analysis of nanosystems' effects on human endothelial and monocytic cell functions.

... L. Bachelet, I. Bertholon, D. Lavigne, R. Vassy, M. Jandrot-Perrus, F. Chaubet and D. Letourneur. 2009. Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets. ...

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Comprehensive proteomic characterization of stem cell-derived extracellular matrices

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

... cells as compared to TCPS culture, indicating that the ECM signatures influence each cell type in 46 a differential fashion.. Materials and methods 51..[r] ...

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Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function

Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function

... *: p<0.05, **: p<0.001. When more than 3 groups were compared a global p-value is: panel A: p=0.006; panel C: p=0.08; panel D: p=0.04. In panel A we also give the p-value of 0.072 for si Ctrl vs siCtrl+VEGF and in ...

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Rôle de l’EG-VEGF (Endocrine Gland Derived-Vascular Endothelial Growth Factor) dans le développement et la progression tumorale placentaire : cas du choriocarcinome

Rôle de l’EG-VEGF (Endocrine Gland Derived-Vascular Endothelial Growth Factor) dans le développement et la progression tumorale placentaire : cas du choriocarcinome

... increased endothelial cells permeability (ECP), a process thought to contribute to tumor cell ...specific endothelial adhesion molecule, ...vein endothelial cells (HUVECs) were used to ...

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PD1/PD-L1 dependent immunosuppression by huiPS-derived cell population

PD1/PD-L1 dependent immunosuppression by huiPS-derived cell population

... Results We demonstrate that these cells are unable to directely activate human lymphocytes, but instead display an immunosuppressive activity on allogenic activated T lymphocytes as shown by a strong inhibition of ...

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Small efficient cell-penetrating peptides derived from scorpion toxin maurocalcine.

Small efficient cell-penetrating peptides derived from scorpion toxin maurocalcine.

... a cell penetrating peptide (CPP) ...the cell entry of proteins, peptides (11), nanoparticles, or drugs such as doxorubicine ...of cell penetration of MCa may vary according to cargo nature, ...

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Increased permeability of blood vessels after reversible electroporation is facilitated by alterations in endothelial cell-to-cell junctions

Increased permeability of blood vessels after reversible electroporation is facilitated by alterations in endothelial cell-to-cell junctions

... the endothelial cell-to-cell junctions and might be the main channel through which macromolecules extravasate after ...labelled cell-to-cell ...of cell-to-cell junctions ...

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