Les cancers professionnels (à l'exception de l'amiante)
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(2) HAL author manuscript ONCOLOGIE / La Revue Francophone de Formation en Oncologie 2007; 9 1-4.
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(20) g. HAL author manuscript. U;7=_<GC cf;8WA+C;8F ^F.C A+C_'G;=GC7P_-SqFPTA@C^_"^F.CBA@A@CX_'A@; PQC7A@;8c>+S= ;7CG AmC7 S_L>dcf>+S= C^_c1GS$=_L>+Ue7PLeC GS`'`C e8cf;WA>@C! D Cq_ G;=XGe7PLSY?7=Cq_ ;7esPLe^_ SqF PLSqW;WAC_ _QS$=c e7Y;A+C`*C=^c AdF!_ SXF `'S >+=_ ~SP4cfC7`'C=^c _QSXF S$==e^_ Um";8FY`C=cfC7P A+C PL>"_,^F.C Um;8FcPQC^_ c"q.C^_ UC G;=GCsP ;sP C8 C`-A@CK Am"C7 S_L>dcf>+S$={;8F ~S$PL`';A@Ue qUC Cq_4cu_F_CGcfeC UmcPLC ;^__QS G>+eC ;8F {AC7F.Ge`*>C_LKhA4moC XS2_L> c>+S= ;8F. inserm-00150018, version 1. G;U`'> F` ;8F G;=GC7P UC A+; PLS_4cf;NcfCKEAmC7 XS2_L>dcf>+S= ;8F c"P>@G A+SPLe8c2 qA@?=C ;F G;=GC7P U^F PLC>|=XKTA+Cq_ >+=_CG8cf>+G>@UC^_E=XS$=3;7PN_QCB=>@G;8F ;8F G;=GC7PN_U^F GC7P$C;7F.K ;F A|`' XS `'Cq_=S= :<SUqY04 >+=>@C=_C8c ;8F `$eA+S `*Cq_u`-FAdcf> A@CX_nT=OC8Fc*e7Y;A@C`C=c'C7= _CsP ^F.C A+C PA+C Um@C7 S_L>dc>VS = _*PLS~C^__L>VS$==CA+A@C$_ U;7=_ A;-_4FP.CB=F.CTUCZG;=GC7PN_Y$X=eGS$AVS$Y>^F2C^_LKCs=Ye=Xe7PL;AGS= _L>@Ue7PLeZGS `'`*CT~f;>VW.A@CKC^_cC8Fc5NcPLC _LSqF_LfC^_4c>+`*e C= PL;>"_LS= U^F ~f;B> W.A@C =S `-WPQC Ume8c"F.UC_SPcf;s=^cu_FPuAC_u~C`*`Cq_ (:<C^_*P >"_"^FCq_ eA+C7eq_UChG;=XGC7PUChA4m@Sq;> PChS$=c!;7PC8 $C`- A@Che8cfeh`'>"_C='e7>UC=XGChG C
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(22) j. HAL author manuscript. C7P4cf;7>+=_xG;=GC7PN_ C8FC=^c C7= CB~~fC8c ~;>|PQC AmSqWs}C8c Um F=XC >+=UC`=>"_;8cf>+S= ;8Fbc>dcPQC UC^_x`';A@;U$>@Cq_ PLS~C^_N_L>VS ==CAA@Cq_& a1=Cec"F.UCPLeGCB=cfC;*GC7C=U;=^c`'S=^cPLe ^F.C _LCFA@C`*CB=c'[ C8c r UC^_ G;q_ >`'qFcf;8WA@C^_ UC_hC7 S_L>dcf>+S=_PLS$~Cq__L>+S ==CA@ACq_W.e=eB~>@G>;>@C=^c UmVF.=C'PLCGS==;>"__L;=XGCC= `*;A@;U$>@C PLS~C^_N_L>VS ==CAA@C " gK+j ]fA _LC`-WA@C ^F.C GCG> PLS^>@C==C C__LC=^cf>+CAA@C`*CB=c Um F=XC ;W._LC=GC U C. inserm-00150018, version 1. UeGA+;7PQ;8c>VS$=XKCAA@C` B`*C U^F.C A@; A@;7PYC `eGS==;>"__L;=XGC UCq_1`eUC^G>+=_1C8cZUC A;uSqFA+;c>+S= UXF PA+C UC^_ ~;GcfC8FPN_ PLS~C^__L>+S ==XCA_ U;=_ A@; _FPC=^F.C UCq_ G;=GCsPN_ D CX_ U>"_;7PL>dcfe_ U C PLCGS$==;>"__L;=GChC='`;A@;U>@CEPLS$~Cq__L>+S ==CA@ACT_CA+S=A@CEc"ChUChG;=GC7PGS=~4>+PL`*C=^cGC8c@cfC qqSqc2 ?_LC! D C^_ G;B=XGC7P_ A+Cq_ `>@C8F PLCGS$==F_ _LS=^c*A@C^_ G;B=XGC7P_uPL;sPLC^_ US=^c'AV;v~SP4cfC ;^__LSG7>+;8cf>+S= ;8.CG F=C =^F.>"_;=GC _eGB>@~> ^F.C C^_4cZW>@CB=OGS$==F.C UC_`*eUCG>+= _ _eG>@;A>"_Leq_ A+Cq_`*e^_QSXc2 XeA|>VS `*C^_' A@C8FPQ;8F ;^__LSGB>VeX_ Am;`>@;=^cfC C8cxA+Cq_ G;=GC7PN_ =;q_LS _L>+=^F_L>@C= _ ;q_N_QS G>@e^_ ;8F K'SXF__L>+?7PLCq_ UC WS>_ =. PLC8$;=G CKUC_ZG;=GCsPN_hUm@S$P> Y >+=C`-FA c>@~;GcfS$P>VCBA+A@CuGS$`'`*CA@CG;=XG^CsPhU^F SqF`'S= _QS$=cWC;8F.GSqF `'S >+=_'W>@CB=OPLCGS$==F_ =^cPQC wr! C8c1kr! UC^_*G;^_*UC G;=XG^CsPU^F SqF`'S$= ;8c@cP> WqF.;7WA@CX_ UCq_ C8 XS2_L>dcf>+S=_ PLS~Cq_N_L>+S==CAA@Cq_ _LC7PQ;B>@C=^c >+=UC`'= >"_QeX_ t > A@C =XS `-WPLC U C G;B=XGC7PN_ U^F SqF.`'S = PLCGS$==^F_3CB=O`*;A;U$>@C PLS~CX__L>+S ==XCBA@A@C ; =C8ccfCs`C=c';8FY`'C=^cfe ;8F{GSqFPN_*UC^_*UC7Pf=>?sPLC^_3;B==XeC^_QK Gqm@C^_4c PL;8c> ^F.CB`*C=^c F=>^F.C`*C=^c C7= PL;>"_LS= Um|F=C C7 S_L>dcf>+S$= Am;`>@;=^cfCK A+Cq_ ;8FcPLC_ G;7=Ge7PLSY?7=C^_qFA@`'S =;>+PLC^_ e8cf;7=^ccSXFs}LSqFPN_A+;7PfYCB`*C=qc!> Y=SPLe^_D ;EPLSSqP"c>+S='UChG;q_PLCGS$==F_Cq_4c WC;8FGSXF AdF_'~f;> WA@C SqFP-A+C^_<G;=GCsPN_'UC A@; .C^__L>CxSXFOA+Cq_'A+CFGe`'>@Cq_ ;7P';7>+AA@C8FP_QK A F_L>@C8FP_ G;7=Ge7PLSY?7=C^_ ;7esPLe^_=C5~>+YqFPLC=^c!;^_U;=_UCq_cf;WAC;8F U Ch`*;BA@;U>@CEPLS ~C^__L>VS ==CAA@CKGS`'`Ch;7P. /( ,!303(-,!)0 .(5 0, %&($,!(;87
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(41) i. HAL author manuscript. C8 $CB`'A@CA@C'G;U`> F`<K A@C<W$e7PAA> F.`'KSXFxA@C-~S$PL`*;AUe q$UCKG^C^F>GS$=cP> WqF.C'e7Y;A@C`C=c<A@;_LSqF_ PLCGS$==;>"__L;=GChUC^_G;B=XGC7PN_PLS$~Cq__L>+S ==CA"_ 4 i MO;A+YPLe'A+Cq_E>+=GC7Pc>dc"F.UC^_LK>+AC^_4c GC7P4cf;s>|= ^F.C-AdF!_L>CFPN_E`'>@AA>@C7P_ UCG;^_ UC'G;=GC7Ph_LS=^c U^F_ G1 ;^FC ;7==Xe^C bUC^_ C8 XS2_L>dcf>+S =_ PQS$~Cq_N_L>VS ==CAA@C^_'CX_ G;7=GC7PN_O_LS=^c UC AdF_ GS=GC=cPLe^_ U;7= _ A@Cq_. inserm-00150018, version 1. G;8cfesYSP>+Cq_1SXFXP >V?7PLCq_LKCcZGsS$=cP> WqF.C=^c5US$=XG ;8F >+=eBY;A+>dcfeq_'_LSG>+;ACq_1UC `'SP4cf;7A+>dcfe C8c5Um>+=GB>@UC=GC UC^_ G;=GCsPN_ D;% C XS2_L> c>+S= PLS$~Cq__L>+S ==CA@AC UC^_ G;=Ge7PLSY?7=C^_ PLe^_C=cfC C7= SXFcPLC UC^_ ;7P4c>VG8FA@;7PL>dcfe_T;sPTPL;sS$P"c UC^_Z~;G8cfC8FP_-A+>@e^_1;8FOGS`-S$P"cfC`'C=^c5Cc5;8F `'SUC UC3>@C GS `'`*C A"C cf;8W$;GTSqFuA % ;BA+>@`C=cf;8c>+S=6^D;% C7 S_L>dcf>+S=C_4cCs=Ye=e7PQ;BA>+=qSA+S$=cf;> PLCZC8cA+Ch A F__LSqF.C=^c> Y =XS$PLeCTUCq_ cPL;8$;>|A@A@C8FPN_GS$=XGC7PL=e^_#=3GS$=cPLC7;7P"c>@CK AVCTPL>_,^F2C-UC-G;s=GC7P;^__LSG>+e -GCq_ C8 S_L>dcf>+S = _ C8FcNcPLC PLCA+;8cf> C`*C=^ch~;GB>@A@CB`*C=^c PLeC=^F.K;7PEF.=CueBA@>`*>|=;7c>+S= UCq_-_F W_cf;7=GCq_ZA@Cq_h A F_Z=SG> .C^_1C8c ;7P F=C'U>`*>|=qFcf>+S= UCq_E=> .C;8F xU&% C7 S_L>dcf>+S$=uYPGC 'Am@;`eA@>+S$PQ;8c>+S= UC^_PQSXcfCGNc>+S=_ GS A+A@CG8cf> Cq_ C8c >+=U$> .>@U^F.CBA@A@C^_1C8c UC^_Z`'S UCq_ZSe7PL;cS> PLC^_C^_1G;7PL;G7cfe7Pf>_4cf>^F.Cq_}QF_c>+~>@C=^c ^F!m@S$=xS$P4cfCF= >+=^cfesP,8c ;7P4c>VG8FA@>@C7P ;8F G;=GC7P_ UmSPL> Y>|=C PLS~CX__L>+S ==XCBA@A"C U^F S$>+=c UC{F.CbUCbA; PLCG CsPLG CbCc A@; PLe8$C=^cf>+S$='. 5 - / [ T] 7Ezh MvS$=XS$YPQ;70 _ S= c2 XC (.;A F.;8cf>+S$= S~ ;PLG>+=SYC7=>@G{zh>"_ 4_ cfS :ZF`';= _QKl1S A [ ii& ]=cfC7P=;c>+S$=;A&7hYC=G7*~S$Pz C^_QC;7PLG 'S=';7=GC7P8\BD(XS=6 wR F.> Y=S= K t;=UqPQC8c . qD C^_ C7 S_L>dc>VS = _ ;8F uPSU^F>dcL_G;B=XGe7PLSY?7=XCX_ !PLC`'>@?7PLCq_ht=c5 X?^_LCq_. =
(42) wi&"[ F>+A@ACcwrr. 6l->+=GC=chzhK1;8F>|=C= (KS$> 404;=XCB= K CUC7P_LC= :<K-SqF=qY z K 1SYC8>+=;q_TM# 75z -K __cf?`'C>+=^cfC7PL=;c>+S=;AU&% >+=~S$PL`*;8cf>+S$= _4FPhA % C XS2_L> c>+S= PLS~C^__L>+S ==XCBA@A@C;8F ;7YC=^cL_ G;=Ge7PQS$Y?7=XC^_.
(43) p. HAL author manuscript. C7= FPLSC!7z e^_4F.Adcf;8cL_ UC^_C^_c>|`*;8cf>+S=_SqFPA+; yPL;=GCEC7=XU;=^cAVC^_;==eC^_h[spprs[spp06q;1 >@C7PN_ U C =SqcfC^_US GF`'C=^cf;> PLCq_ :ZY >@?=ChC8c_LeGFP>dcfehU^F-cPL;;7>@A T [sjgK&C c"Pf>|`*Cq_4cPQC[sppp kt>+C`>@;8cG 4 > K zh>@G ;7PQU _LS=D KtqcPL;7>+~(1K D ;8cPLC>+AA@C . K.D ; 40 ;B=>z K;B`'WCAAtK z SXF__LC;8FuMvK. S$~~fC8c"cf;; 7D >_4cf>+=qY*S GG8F;8c>+S=;AG;7PLG>+=SYC= _ =q>+PNS= :<C;Adc2 C7PN_fCG8c wrrqk [ [w/7[ s \"[kkj p . inserm-00150018, version 1. & ;1 ` t!:<K A+;>+P 7 nTGG8F;8c>+S=;AG;=XGC7P;`'S =Y<<S`'C=\B XC7PLC ;7C <CEWCC=';=UT XC7PLCh;7PC <CEYS$>+=qY 7Z` ]=UTM CU6wrr0 kk!\ gj g6]`-WC7PL=S=. _4c>+`*;8c>+S= U^F =S `-WPQCuUCuG^;_ZUC GC7P4cf;7>+= _1G;=XGC7PN_Z;c"cP> WqF.;7WA@CX_ uUC^_Z~;GcfC8FPN_. PLS~C^_N_L>VS ==CA"_*C= yPL;=XGC!]= _c> c"FcZUC $CB>+A@AC _L;=>dcf;>+PLCK(:'es;7P4cfC7`'C=c'_L;7=cfe c"PL;;>A+Kwi Kwrr0. ;7PYC;WA@CT_FP TZ >+=q_ _L;=^cfC ~"P . cfe7AVeG. j6zh;sS$P"c UCA+; S`'`>"__L>+S = >+=_4cf>dc"F.eC;7PZA % ;7Pc>+GA"CD[sjg4w U^F GS UCuUCuA+; teG8FPL>dcfe _QS G>@;ACK F.>+=-wrr&. i&1;^_W>@ CB=;_N_LSqF.A|>l dK]L`-WC7PL=S=. K ]4<;NcL_4FWS . K F>__LS= KRTSA+UqWC7PfY M S=~"PLS=^cf;8c>+S=. UC^_<G;=Ge7PLSY?7=C_';7.e7PLe^_<C= `>A@>@C8F UC cPL;8;>+AhCc1UC^_Tcf;8WA@C;F vUC `*;A;U$>@C^_1PLS ~C^__L>+S==CAA@C^_ ]=_4cf>dc"Fc. UC. C>+AA@C. ZT d>+=q_ _L;=^cfC! ~"P; . _L;=>dcf;>+PLCK :<e7;7P4cfC`'C=c. _L;s=^cfe. cPL;8;>+A+K wrr. ;sPYC;7WA@C _4FP. cfeA+eG.
(44) [sr. HAL author manuscript. ;8WA@C;8F [ . S_L>dcf>+S= _'PLS ~C__L>+S ==CA@AC_uGA@;^__LeCX_';sPA@C ]zh GS$`'`*C G;=XGe7PLSY?7=Cq_'SqFP. Am S``*C
(45) . . !#"$%$&'(&)$!*,+.- "$%- +$*/+. inserm-00150018, version 1. !#"$%$&'(&)$!*G+9" 4 - >/& 0#"1+9+#- I>/&+JB%&LK?"- + P - 4 - 6&(6>Q- +*/%4 4 - $& RS'T- $?&+ )>@"'U*V- W1?&+ $)[%<*4 'T- $!&)] RS>,+&)$- 6. XFK?&)$Y- B- $!&3. )'8- $!"O/Z)O,B - [%<7)$4 &!3. RS>,+7)$- 1>,&_B&L`4 4 - 1)' a7)>@4 4 - 1' Mb<%>@"'2&L<?&c!N)4 &)$!* dG- 6#e&4#X,6&H>,*/%- $?+J6"'2[")+97+f] M B)'T- 1' gS1- 4 &+JB)&2+f6!<%- +*@& h "1?B>@"$+J&*GK>,- +iB%&L<?"1%- 4 4 & P 1- &+ gS1- 4 &+i'T- $!7)>@4 &+3j[&)12"1k$!"$_>/D@D/- $7&!+ a&)$YI)$& Mb<4 ">=1>/&_B&2N)- $!)4 & m")>='(%4 B)7)<B)& a- +X,6#<4 ")>/")'27!*F<!4 ]=7!*F<&> n c#B&_Bo 7*F<4 I)$!& \3@p3@q!3sr2t MGuGuvX=B- "!c- $&] a)>/"1%- 4 4 )>,B+iBo 6#- B)&!+DC">w*/+J6")$?*/&)$!)$*jB)&T4 o !6- B%&_+x1%4 D/1>V- W1!& h Y.'."1!*,)>@B)& tj)K`- +'.&k[!++- D. 0#"1'2"$!354 &)1!67)'8- &+93:"%+3;*=<?>@"!ACB&3ED@"- &3 )1*F>@&+ 0#&)1!3G'.74 H$?")'(& M !N)- */7#+.$+9")O/+!- $)1!+!- &)$$&+ 0#"1'2"$ \)O &++- & ^ 0#&)1 0#"1'2"$ 0#"1'2"$ 0#"1'2"$ 0#"1'2"$ 0#"1'2"$ M !N)- */7#+.$+9")O/+!- $)1!+!- &)$$&+ 0#"1'2"$ 0#&)1 0#&)1!3G[!"1)'U"$!3N#&++- & 0#&)1!3G[!"1)'U"$ 0#&)1!3G[!"1)'U"$!3N#&++- & lf&)1?6f7)'8- & m"- &_X=)$`- "+f>,6f"'.&)] d +f"[<)>)$!c 0#"1'2"$ lf&)1?6f7)'8- & tb"1+J6)$!6&H>,+J6"'2K- $7!+ lf)>wH$!c!3S[!"1)'."$ 0#"1'2"$!3NH"- &+J)>,7H>w"O,B- `%&#+*V- N&+J+1)[?7H>Q- &)1%>@&+ 0#"1'2"$.
(46) [[. HAL author manuscript. ;8WA@C;8F w !PLS$~fC^__L>+S =_ SXF >+=U^F_cP >VCX_ GA@;^__LeCq_ ;sP A+C ]4z GS`'`*C G;=Ge7PQS$Y?7=C_ SqFP Am S``*C. inserm-00150018, version 1. bV )! Gj F R
(47) 4 1'T- $- 1' XV[>,"B16*V- "$2B ] RS1)>,H'T- $!&LX=D@)K>Q- 6!*V- "$8 B ] `%&)$!*/LX=D@)K>Q- 6!*V- "$] M ")1*@6#<?"1!6.XV- $B1+*=>=- &_B)1%] Mb<)>/K?"$_X,`)+7)- D=- 6!*V- "$] M "e&_XV[)>@"%B1!6*V- "$_B&)] m"$B&)> - &_B&_DC"$*@&_&#*GB 6!- &)> Mb<)1?+f+1)>,&#+X=Ds)K>Q- 6!*V- "$_&!*S>,7)[>/!*V- "$)] gb7)'.*=- */&LX,&!c#*F>,!6f*Q- "$_+9"1?*s&)>,>/- $?&_N.&c)[!")+!- *V- "$_1k>@B"$%]
(48) F+"[>,")[)$!"4#X=D@HK%>=- 6*V- "$2B)&T4 ]XF[%>@")67B% 7 k4 !6- B&LD">@*=] &)1%K4 &#+iX=D@)K>Q- 6!*V- "$)]G&*j7)K!7)$- +*,&H>Q- & 0#&- $!*F>/&!+.
(49) [w. HAL author manuscript. ;8WA@C;8F S`-WPLChUC cPL;;>+AA@C8FPN_C7 XS2_Qe^_C7=-yPL;=XGC ^F.CA^F.C_G;=Ge7PLSY?7=XC^_. inserm-00150018, version 1. C .
(50) . j . RG>/+9&)$- 6 a&)$?YfI)$?& a7)>w4 4 - 1' a)>,"1%- 4 4 )>/B+Bo 6!- B%&#+DC">@*/+J6")$*/&)$!)$?*bB%&k4 o #6?- B)&_+1%4 D/1>Q- W1!& MB)'k- 1' Mj<4 ">F1>,&_B&(N%- $H)4 & Mj<)>@"'(&_<&cH!N%4 &)$!* m")>='2)4 B)7)<B)& gHB)>,"6>FK%1>/&+ )>@")'2*F- W1?&#+.[!" 4 H696#4 - W)1&+ dG- 6#e&4 n c!HB&_Bo 7*=<4 I)$!& 0!"1?++!- I>,&+JB)&_K"- + P - 4 - 6&26>V- +*/%4 4 - $?&. \. Z. q ! \ . Z \%\ r ? r p ! \ ! !p. r . . Z)r O O \r O ! r ) p \ ) r O pr \)q.
(51)
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