Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo.

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Submitted on 8 Sep 2008

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Nonoverlapping functions of DNA polymerases mu,

lambda, and terminal deoxynucleotidyltransferase

during immunoglobulin V(D)J recombination in vivo.

Barbara Bertocci, Annie de Smet, Jean-Claude Weill, Claude-Agnès Reynaud

To cite this version:

Barbara Bertocci, Annie de Smet, Jean-Claude Weill, Claude-Agnès Reynaud. Nonoverlap-ping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase dur-ing immunoglobulin V(D)J recombination in vivo.. Immunity, Elsevier, 2006, 25 (1), pp.31-41. �10.1016/j.immuni.2006.04.013�. �inserm-00319559�

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Fig. 1 CDR3 length (bp) % of sequ ences 0 10 20 30 40 0 3 6 9 12 15 18 21 24 27 30 pol µ -/-pol µ/TdT -/-Vκ41-Jκ1 0 3 6 9 12 15 18 21 24 27 30 -9-8 0 10 20 30 40 0 3 6 9 12 15 18 21 24 27 30 0 10 20 30 40 50 60 70 Vκ-Jκ1 +/+ TdT -/-0 10 20 30 40 50 60 70 0 3 6 9 12 15 18 21 24 27 30

Figure

Fig. 1 CDR3 length (bp)% ofsequences010203040036912151821242730pol µ-/-pol µ/TdT  -/-Vκ41-Jκ10369 12 15 18 21 24 27 30-9-8010203040036912 15 18 21 24 27 300102030405060Vκ-Jκ170+/+TdT -/-01020304050607003691215 1821242730
Fig. 1 CDR3 length (bp)% ofsequences010203040036912151821242730pol µ-/-pol µ/TdT -/-Vκ41-Jκ10369 12 15 18 21 24 27 30-9-8010203040036912 15 18 21 24 27 300102030405060Vκ-Jκ170+/+TdT -/-01020304050607003691215 1821242730 p.2

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