Regulatory T cell plasticity: another layer of complexity in atherosclerosis

The present study investigated the effect of combined RAPA/MR1 treatment on rat-to-mouse islet xenograft survival and analyzed the role of CD4 + CD25 + Foxp3 + T regulatory cells

9–13 In this review, we will try to give an overview of the functions of immune cells in the regulation of atherosclerosis with particular emphasis on regu- latory B cells

Following binding to CD4, tregalizumab induces a T-cell receptor (TCR) signaling pathway that is incomplete and unique when compared with OKT3 and other anti-CD4 antibodies, but that

The impaired CD4 T cell response of TSSP-deficient mice to HEL correlated with significant alteration of the dominant TCR- chain repertoire expressed by HEL-specific CD4 T

We show here that hybridoma cells expressing a chimeric TCR-b chain (bIII) containing intracellular and transmembrane TCR-g amino acids, together with a wild-type TCR-a (awt)

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Follicular regulatory T cells can be specific for the immunizing antigen and derive

More direct and convincing evidence for a role of adaptive immunity in atherosclerosis has been provided using experimental mouse models of atherosclerosis, especially Apolipoprotein

The TME is in particular composed of immune cells including T cell subsets (follicular helper T cells [Tfh], regulatory T cells [Treg]), stromal cells, dendritic cells, and