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Low-dose sufentanil does not potentiate intrathecal morphine for perioperative analgesia after major colorectal surgery

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Low-dose sufentanil does not potentiate intrathecal morphine for perioperative analgesia after major colorectal surgery

CULEBRAS, Javier, et al.

Abstract

Both intrathecal sufentanil (ITS) and intrathecal morphine (ITM) improve analgesia in obstetrical or cardiac procedures. From a pharmacokinetic standpoint, combining these two opioids may improve perioperative analgesia. We performed a prospective randomized double-blind study to compare the analgesic efficacy of ITM alone vs a mixture of a low dose of ITS plus ITM for perioperative pain relief in colorectal surgery.

CULEBRAS, Javier, et al . Low-dose sufentanil does not potentiate intrathecal morphine for perioperative analgesia after major colorectal surgery. Canadian Journal of Anesthesia , 2007, vol. 54, no. 10, p. 811-7

DOI : 10.1007/BF03021708 PMID : 17934162

Available at:

http://archive-ouverte.unige.ch/unige:43101

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