Linking PCNA-dependent replication and ATR by human Claspin.

HAL Id: inserm-00147047

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Submitted on 15 May 2007

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Linking PCNA-dependent replication and ATR by

human Claspin.

Jean-Marc Brondello, Bernard Ducommun, Anne Fernandez, Ned Lamb

To cite this version:

Jean-Marc Brondello, Bernard Ducommun, Anne Fernandez, Ned Lamb. Linking PCNA-dependent replication and ATR by human Claspin.. Biochemical and Biophysical Research Communications, Elsevier, 2007, 354 (4), pp.1028-33. �10.1016/j.bbrc.2007.01.091�. �inserm-00147047�

HsClaspin

T

S

I

MCM2

PRK

B

C

_HsClaspin

-

+

: Nuclease

I

I

S

S

T

T

AS

HU

HsClaspin

D

PCNA

A

Fig.1 Brondello et al.

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+

Peptide:

CLN#24

commercial

-

+

-

+

HU:

HsClaspin

220

170

116

-

+