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Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes

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Academic year: 2021

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Figure 1. Characteristics of CEY proteins. (A) Phylogenetic tree showing a relation between CEYs and Y-box-binding proteins in other organisms, the closest being Yps in Drosophila melanogaster
Figure 2. CEY proteins are essential for fertility. Light micrographs from live wild-type and mutant animals grown at the indicated temperatures.
Figure 3. Germline defects in the absence of CEY proteins. Gonads were either not injected (uninjected), control injected (mock RNAi) or injected with RNAi clones targeting both cey-2 and cey-3 (cey-2,-3 RNAi)
Figure 4. CEYs are required for the integrity of germline mRNPs. (A) FLAG IPs performed in the presence or absence of RNAse on extracts from transgenic animals expressing either FLAG-CEY-2 or FLAG-CEY-4
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